GSE313324 Data Processing

geo_data_processing 2 steps

Publication

Integrative CRISPR Screening and RNA Analyses Discover an Essential Role for PUF60 Interactions with 3' Splice Sites in Cancer Progression.

Cancer research (2025) — PMID 41411621

Dataset

GSE313324

PUF60-Mediated Splicing Is a Key Driver of Triple Negative Breast Cancer [CRISPR]

Warning: Pipeline descriptions and code snippets may be inferred or AI-generated. Use them only as a starting point to guide analysis, and validate before use.

Processing Steps

Generate Jupyter Notebook
  1. 1

    The MAGeCK software package version 0.5.4 was used to statistically identify RBP candidates with a Wald P value < 0.05 and bet score < 0

  2. 2

    Library strategy: CRISPR Screen

Raw Source Text 
The MAGeCK software package version 0.5.4 was used to statistically identify RBP candidates with a Wald P value < 0.05 and bet score < 0
Assembly: GRCh38
Supplementary files format and content: Supplementary files format and content: csv file includes beta score, Wald P value, and FDR for each RBP, essential gene, and non-targeting sgRNA with respect to each cell line the screen was performed in
Library strategy: CRISPR Screen
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