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GSE146916

GSE GEO
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A role for alternative splicing in circadian control of insulin secretion and glucose homeostasis

Organism: Mus musculus
Platform: GPL19057
Samples: 23
Experiment Types:
Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing Other
Submitted: Mar 12 2020
Last Updated: Aug 13 2020
Status: Public on Aug 10 2020
Contact: Mark,,Perelis (University of California San Diego)

Relations

BioProject: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA612358 SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRP252642

Summary

We report the discovery of circadian clock-controlled alterantive pre-mRNA splicing in pancreatic beta cells and its role in insulin secretion. We performed RNA-sequencing in CRISPR-CAS9 edited Clock and Bmal1 knockout BetaTC6 cells and used differential mRNA expression and splicing analysis to identify and validate transcriptional and alternative splicing targets of the circadian clock regulating insulin secretion.

Overall Design

We have profiled the transcriptomes of wild type and Bmal1 knockout pancreatic beta cells by RNA-seq and performed ChIP-seq and eCLIP-seq to map the DNA and RNA binding positions of the RNA binding protein THRAP3 in these cells.

Analysis (4 steps)

View Data Processing
Processing steps for GSE146916
  1. Sequencing on Illumina NextSeq500 and basecalling by Real-Time Analysis (RTA) software version 2.4.11
  2. Alignment to the mm10 genome using STAR version 2.5.0
  3. mRNA quantitation using featureCounts version 1.5.3 and the option “–t exon” was specified to count mRNA features
  4. Differential expression using DESeq2 version 1.22.1 specifying a false discovery cutoff of 0.01 for independent filtering

Supplementary Files (4)

GSE146916_DESeq2res_WT_BKO.csv.gz Download
GSE146916_DESeq2res_WT_CKO.csv.gz Download
GSE146916_RAW.tar Download
GSE146916_tpm.csv.gz Download
GEO Samples (23)
GSM4409569 GSM4409570 GSM4409571 GSM4409572 GSM4409573 GSM4409574 GSM4409575 GSM4409576 GSM4409577 GSM4718539 GSM4718540 GSM4718541 GSM4718542 GSM4718543 GSM4718544 GSM4718545 GSM4718546 GSM4718547 GSM4718548 GSM4718549 GSM4718550 GSM4718551 GSM4718552

Dataset Citations (1)

A role for alternative splicing in circadian control of exocytosis and glucose homeostasis.
PMID 32616519 · 2020 · Genes & development
Biliana Marcheva, Mark Perelis, Benjamin J Weidemann, Akihiko Taguchi, Haopeng Lin, Chiaki Omura, Yumiko Kobayashi, Marsha V Newman, Eugene J Wyatt, Elizabeth M McNally, Jocelyn E Manning Fox, Heekyung Hong, Archana Shankar, Emily C Wheeler, Kathryn Moynihan Ramsey, Patrick E MacDonald, Gene W Yeo, Joseph Bass

SRA Experiments (23) and Runs (23)

Total: 24090 MB
SRX7906131 SRP252642 RNA-Seq PAIRED
GSM4409569: RNA-seq from wild type BetaTC6 cells 1; Mus musculus; RNA-Seq
Sample: SRS6313742
BioProject: PRJNA612358
BioSample: SAMN14371108
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BetaTC6 cells from ATCC (CRL- 11506)
cell type: derived from insulinoma
mutations: None
passages: 5-15 passages
Original files (1)
BetaTC6 cells from ATCC (CRL- 11506)
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR11300801 26783983 4044450359 1417.63 WT_RNA_1_R1.fastq, WT_RNA_1_R2.fastq, SRR11300801, SRR11300801.lite SRA
SRX7906132 SRP252642 RNA-Seq PAIRED
GSM4409570: RNA-seq from wild type BetaTC6 cells 2; Mus musculus; RNA-Seq
Sample: SRS6313743
BioProject: PRJNA612358
BioSample: SAMN14371107
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BetaTC6 cells from ATCC (CRL- 11506)
cell type: derived from insulinoma
mutations: None
passages: 5-15 passages
Original files (1)
BetaTC6 cells from ATCC (CRL- 11506)
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR11300802 24397004 3684197728 1292.3 WT_RNA_2_R1.fastq, WT_RNA_2_R2.fastq, SRR11300802, SRR11300802.lite SRA
SRX7906133 SRP252642 RNA-Seq PAIRED
GSM4409571: RNA-seq from wild type BetaTC6 cells 3; Mus musculus; RNA-Seq
Sample: SRS6313744
BioProject: PRJNA612358
BioSample: SAMN14371106
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BetaTC6 cells from ATCC (CRL- 11506)
cell type: derived from insulinoma
mutations: None
passages: 5-15 passages
Original files (1)
BetaTC6 cells from ATCC (CRL- 11506)
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR11300803 22002499 3322349934 1172.28 WT_RNA_3_R1.fastq, WT_RNA_3_R2.fastq, SRR11300803, SRR11300803.lite SRA
SRX7906134 SRP252642 RNA-Seq PAIRED
GSM4409572: RNA-seq from Bmal1 knockout BetaTC6 cells 1; Mus musculus; RNA-Seq
Sample: SRS6313745
BioProject: PRJNA612358
BioSample: SAMN14371105
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BetaTC6 cells from ATCC (CRL- 11506)
cell type: derived from insulinoma
mutations: CRISPR-CAS9 mediated deletion of Exon 8 in Bmal1
passages: 5-15 passages
Original files (1)
BetaTC6 cells from ATCC (CRL- 11506)
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR11300804 26653327 4025365314 1407.5 BKO_RNA_1_R1.fastq, BKO_RNA_1_R2.fastq, SRR11300804, SRR11300804.lite SRA
SRX7906135 SRP252642 RNA-Seq PAIRED
GSM4409573: RNA-seq from Bmal1 knockout BetaTC6 cells 2; Mus musculus; RNA-Seq
Sample: SRS6313746
BioProject: PRJNA612358
BioSample: SAMN14371104
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BetaTC6 cells from ATCC (CRL- 11506)
cell type: derived from insulinoma
mutations: CRISPR-CAS9 mediated deletion of Exon 8 in Bmal1
passages: 5-15 passages
Original files (1)
BetaTC6 cells from ATCC (CRL- 11506)
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR11300805 35102766 5301277468 1862.65 BKO_RNA_2_R1.fastq, BKO_RNA_2_R2.fastq, SRR11300805, SRR11300805.lite SRA
SRX7906136 SRP252642 RNA-Seq PAIRED
GSM4409574: RNA-seq from Bmal1 knockout BetaTC6 cells 3; Mus musculus; RNA-Seq
Sample: SRS6313747
BioProject: PRJNA612358
BioSample: SAMN14371103
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BetaTC6 cells from ATCC (CRL- 11506)
cell type: derived from insulinoma
mutations: CRISPR-CAS9 mediated deletion of Exon 8 in Bmal1
passages: 5-15 passages
Original files (1)
BetaTC6 cells from ATCC (CRL- 11506)
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR11300806 23466217 3543937337 1271.03 BKO_RNA_3_R1.fastq, BKO_RNA_3_R2.fastq, SRR11300806, SRR11300806.lite SRA
SRX7906137 SRP252642 RNA-Seq PAIRED
GSM4409575: RNA-seq from Clock knockout BetaTC6 cells 1; Mus musculus; RNA-Seq
Sample: SRS6313748
BioProject: PRJNA612358
BioSample: SAMN14371102
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BetaTC6 cells from ATCC (CRL- 11506)
cell type: derived from insulinoma
mutations: CRISPR-CAS9 mediated deletion of Exons 6-7 in Clock
passages: 5-15 passages
Original files (1)
BetaTC6 cells from ATCC (CRL- 11506)
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR11300807 24364188 3679106255 1300.18 CKO_RNA_1_R1.fastq, CKO_RNA_1_R2.fastq, SRR11300807, SRR11300807.lite SRA
SRX7906138 SRP252642 RNA-Seq PAIRED
GSM4409576: RNA-seq from Clock knockout BetaTC6 cells 2; Mus musculus; RNA-Seq
Sample: SRS6313749
BioProject: PRJNA612358
BioSample: SAMN14371101
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BetaTC6 cells from ATCC (CRL- 11506)
cell type: derived from insulinoma
mutations: CRISPR-CAS9 mediated deletion of Exons 6-7 in Clock
passages: 5-15 passages
Original files (1)
BetaTC6 cells from ATCC (CRL- 11506)
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR11300808 19757560 2983354956 1085.87 CKO_RNA_2_R1.fastq, CKO_RNA_2_R2.fastq, SRR11300808, SRR11300808.lite SRA
SRX7906139 SRP252642 RNA-Seq PAIRED
GSM4409577: RNA-seq from Clock knockout BetaTC6 cells 3; Mus musculus; RNA-Seq
Sample: SRS6313750
BioProject: PRJNA612358
BioSample: SAMN14371110
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BetaTC6 cells from ATCC (CRL- 11506)
cell type: derived from insulinoma
mutations: CRISPR-CAS9 mediated deletion of Exons 6-7 in Clock
passages: 5-15 passages
Original files (1)
BetaTC6 cells from ATCC (CRL- 11506)
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR11300809 21248958 3208508065 1130.2 CKO_RNA_3_R1.fastq, CKO_RNA_3_R2.fastq, SRR11300809, SRR11300809.lite SRA
SRX8920078 SRP252642 ChIP-Seq SINGLE
GSM4718539: WT_THRAP3_ChIPseq_rep1; Mus musculus; ChIP-Seq
Sample: SRS7176626
BioProject: PRJNA612358
BioSample: SAMN15776050
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: WT_THRAP3_ChIPseq
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: None
passages: 5-15 passages
antibody: THRAP3 antibody, Novus Biologicals, Cat. # NB100-40848, lot A1
Original files (1)
WT_THRAP3_ChIPseq
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424181 17966646 1356395896 567.53 WT_THRAP3_ChIPseq_rep1.fq.gz, SRR12424181, SRR12424181.lite SRA
SRX8920079 SRP252642 ChIP-Seq SINGLE
GSM4718540: WT_THRAP3_ChIPseq_rep2; Mus musculus; ChIP-Seq
Sample: SRS7176627
BioProject: PRJNA612358
BioSample: SAMN15776049
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: WT_THRAP3_ChIPseq
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: None
passages: 5-15 passages
antibody: THRAP3 antibody, Novus Biologicals, Cat. # NB100-40848, lot A1
Original files (1)
WT_THRAP3_ChIPseq
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424182 18274963 1379876699 578.3 WT_THRAP3_ChIPseq_rep2.fq.gz, SRR12424182, SRR12424182.lite SRA
SRX8920080 SRP252642 ChIP-Seq SINGLE
GSM4718541: WT_THRAP3_ChIPseq_Input; Mus musculus; ChIP-Seq
Sample: SRS7176628
BioProject: PRJNA612358
BioSample: SAMN15776046
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: WT_THRAP3_ChIPseq_Input
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: None
passages: 5-15 passages
Original files (1)
WT_THRAP3_ChIPseq_Input
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424183 16169264 1220912710 513.4 WT_THRAP3_ChIPseq_Input.fq.gz, SRR12424183, SRR12424183.lite SRA
SRX8920081 SRP252642 OTHER SINGLE
GSM4718542: WT_THRAP3_eCLIP_IP1; Mus musculus; OTHER
Sample: SRS7176629
BioProject: PRJNA612358
BioSample: SAMN15776044
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: WT_THRAP3_eCLIP
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: None
passages: 5-15 passages
antibody: THRAP3 antibody, Novus Biologicals, Cat. # NB100-40848, lot A1
Original files (1)
WT_THRAP3_eCLIP
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424184 60380141 4347370152 1784.56 WT_THRAP3_eCLIP_IP1.fastq.gz, SRR12424184, SRR12424184.lite SRA
SRX8920082 SRP252642 OTHER SINGLE
GSM4718543: WT_THRAP3_eCLIP_IP2; Mus musculus; OTHER
Sample: SRS7176630
BioProject: PRJNA612358
BioSample: SAMN15776042
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: WT_THRAP3_eCLIP
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: None
passages: 5-15 passages
antibody: THRAP3 antibody, Novus Biologicals, Cat. # NB100-40848, lot A1
Original files (1)
WT_THRAP3_eCLIP
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424185 31460421 2265150312 930.91 WT_THRAP3_eCLIP_IP2.fastq.gz, SRR12424185, SRR12424185.lite SRA
SRX8920083 SRP252642 OTHER SINGLE
GSM4718544: WT_THRAP3_eCLIP_input1; Mus musculus; OTHER
Sample: SRS7176631
BioProject: PRJNA612358
BioSample: SAMN15776041
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: WT_THRAP3_eCLIP_input
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: None
passages: 5-15 passages
Original files (1)
WT_THRAP3_eCLIP_input
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424186 52349833 3769187976 1548.13 WT_THRAP3_eCLIP_input1.fastq.gz, SRR12424186, SRR12424186.lite SRA
SRX8920084 SRP252642 OTHER SINGLE
GSM4718545: WT_THRAP3_eCLIP_input2; Mus musculus; OTHER
Sample: SRS7176632
BioProject: PRJNA612358
BioSample: SAMN15776039
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: WT_THRAP3_eCLIP_input
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: None
passages: 5-15 passages
Original files (1)
WT_THRAP3_eCLIP_input
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424187 38563384 2776563648 1138.0 WT_THRAP3_eCLIP_input2.fastq.gz, SRR12424187, SRR12424187.lite SRA
SRX8920085 SRP252642 ChIP-Seq SINGLE
GSM4718546: BKO_THRAP3_ChIPseq_rep1; Mus musculus; ChIP-Seq
Sample: SRS7176633
BioProject: PRJNA612358
BioSample: SAMN15776048
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BKO_THRAP3_ChIPseq
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: CRISPR-CAS9 mediated deletion of Exon 8 in Bmal1
passages: 5-15 passages
antibody: THRAP3 antibody, Novus Biologicals, Cat. # NB100-40848, lot A1
Original files (1)
BKO_THRAP3_ChIPseq
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424188 18245520 1377831529 580.24 BKO_THRAP3_ChIPseq_rep1.fq.gz, SRR12424188, SRR12424188.lite SRA
SRX8920086 SRP252642 ChIP-Seq SINGLE
GSM4718547: BKO_THRAP3_ChIPseq_rep2; Mus musculus; ChIP-Seq
Sample: SRS7176634
BioProject: PRJNA612358
BioSample: SAMN15776047
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BKO_THRAP3_ChIPseq
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: CRISPR-CAS9 mediated deletion of Exon 8 in Bmal1
passages: 5-15 passages
antibody: THRAP3 antibody, Novus Biologicals, Cat. # NB100-40848, lot A1
Original files (1)
BKO_THRAP3_ChIPseq
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424189 20477512 1546327215 650.84 BKO_THRAP3_ChIPseq_rep2.fq.gz, SRR12424189, SRR12424189.lite SRA
SRX8920087 SRP252642 ChIP-Seq SINGLE
GSM4718548: BKO_THRAP3_ChIPseq_Input; Mus musculus; ChIP-Seq
Sample: SRS7176635
BioProject: PRJNA612358
BioSample: SAMN15776037
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BKO_THRAP3_ChIPseq_Input
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: CRISPR-CAS9 mediated deletion of Exon 8 in Bmal1
passages: 5-15 passages
Original files (1)
BKO_THRAP3_ChIPseq_Input
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424190 15101995 1140330514 476.87 BKO_THRAP3_ChIPseq_Input.fq.gz, SRR12424190, SRR12424190.lite SRA
SRX8920088 SRP252642 OTHER SINGLE
GSM4718549: BKO_THRAP3_eCLIP_IP1; Mus musculus; OTHER
Sample: SRS7176636
BioProject: PRJNA612358
BioSample: SAMN15776036
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BKO_THRAP3_eCLIP
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: CRISPR-CAS9 mediated deletion of Exon 8 in Bmal1
passages: 5-15 passages
antibody: THRAP3 antibody, Novus Biologicals, Cat. # NB100-40848, lot A1
Original files (1)
BKO_THRAP3_eCLIP
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424191 30515452 2197112544 907.48 BKO_THRAP3_eCLIP_IP1.fastq.gz, SRR12424191, SRR12424191.lite SRA
SRX8920089 SRP252642 OTHER SINGLE
GSM4718550: BKO_THRAP3_eCLIP_IP2; Mus musculus; OTHER
Sample: SRS7176637
BioProject: PRJNA612358
BioSample: SAMN15776035
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BKO_THRAP3_eCLIP
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: CRISPR-CAS9 mediated deletion of Exon 8 in Bmal1
passages: 5-15 passages
antibody: THRAP3 antibody, Novus Biologicals, Cat. # NB100-40848, lot A1
Original files (1)
BKO_THRAP3_eCLIP
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424192 23115600 1664323200 685.17 BKO_THRAP3_eCLIP_IP2.fastq.gz, SRR12424192, SRR12424192.lite SRA
SRX8920090 SRP252642 OTHER SINGLE
GSM4718551: BKO_THRAP3_eCLIP_input1; Mus musculus; OTHER
Sample: SRS7176638
BioProject: PRJNA612358
BioSample: SAMN15776034
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BKO_THRAP3_eCLIP_input
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: CRISPR-CAS9 mediated deletion of Exon 8 in Bmal1
passages: 5-15 passages
Original files (1)
BKO_THRAP3_eCLIP_input
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424193 44366065 3194356680 1317.63 BKO_THRAP3_eCLIP_input1.fastq.gz, SRR12424193, SRR12424193.lite SRA
SRX8920091 SRP252642 OTHER SINGLE
GSM4718552: BKO_THRAP3_eCLIP_input2; Mus musculus; OTHER
Sample: SRS7176639
BioProject: PRJNA612358
BioSample: SAMN15776033
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Mus musculus
Sample attributes
source_name: BKO_THRAP3_eCLIP_input
strain background: C57BL/6
cell type: derived from insulinoma from transgenic mice
mutations: CRISPR-CAS9 mediated deletion of Exon 8 in Bmal1
passages: 5-15 passages
Original files (1)
BKO_THRAP3_eCLIP_input
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12424194 16028220 1154031840 471.03 BKO_THRAP3_eCLIP_input2.fastq.gz, SRR12424194, SRR12424194.lite SRA

Linked Publications (1)

A role for alternative splicing in circadian control of exocytosis and glucose homeostasis.
Genes & development · 2020

Potentially Related Publications (1)

This accession was text-mined from the PMC full text of these publications. It may be referenced for comparison or reused from another study rather than generated for them.

A role for alternative splicing in circadian control of exocytosis and glucose homeostasis.
Genes & development · 2020

Data Files (46)

Accession File Name Stored Type Output Type Mapping Assembly Size Download
— BKO_THRAP3_ChIPseq_Input.fq.gz ChIP-Seq 476.9 MB link
— BKO_THRAP3_ChIPseq_rep1.fq.gz ChIP-Seq 580.2 MB link
— BKO_THRAP3_ChIPseq_rep2.fq.gz ChIP-Seq 650.8 MB link
— SRR12424181_GSM4718539 ChIP-Seq 567.0 MB link
— SRR12424182_GSM4718540 ChIP-Seq 578.0 MB link
— SRR12424183_GSM4718541 ChIP-Seq 513.0 MB link
— SRR12424188_GSM4718546 ChIP-Seq 580.0 MB link
— SRR12424189_GSM4718547 ChIP-Seq 650.0 MB link
— SRR12424190_GSM4718548 ChIP-Seq 476.0 MB link
— WT_THRAP3_ChIPseq_Input.fq.gz ChIP-Seq 513.4 MB link
— WT_THRAP3_ChIPseq_rep1.fq.gz ChIP-Seq 567.5 MB link
— WT_THRAP3_ChIPseq_rep2.fq.gz ChIP-Seq 578.3 MB link
— BKO_THRAP3_eCLIP_input1.fastq.gz OTHER 1.3 GB link
— BKO_THRAP3_eCLIP_input2.fastq.gz OTHER 471.0 MB link
— BKO_THRAP3_eCLIP_IP1.fastq.gz OTHER 907.5 MB link
— BKO_THRAP3_eCLIP_IP2.fastq.gz OTHER 685.2 MB link
— SRR12424184_GSM4718542 OTHER 1.7 GB link
— SRR12424185_GSM4718543 OTHER 930.0 MB link
— SRR12424186_GSM4718544 OTHER 1.5 GB link
— SRR12424187_GSM4718545 OTHER 1.1 GB link
— SRR12424191_GSM4718549 OTHER 907.0 MB link
— SRR12424192_GSM4718550 OTHER 685.0 MB link
— SRR12424193_GSM4718551 OTHER 1.3 GB link
— SRR12424194_GSM4718552 OTHER 471.0 MB link
— WT_THRAP3_eCLIP_input1.fastq.gz OTHER 1.5 GB link
— WT_THRAP3_eCLIP_input2.fastq.gz OTHER 1.1 GB link
— WT_THRAP3_eCLIP_IP1.fastq.gz OTHER 1.7 GB link
— WT_THRAP3_eCLIP_IP2.fastq.gz OTHER 930.9 MB link
— BKO_RNA_1_R1.fastq RNA-Seq 1.4 GB link
— BKO_RNA_2_R1.fastq RNA-Seq 1.8 GB link
— BKO_RNA_3_R1.fastq RNA-Seq 1.2 GB link
— CKO_RNA_1_R1.fastq RNA-Seq 1.3 GB link
— CKO_RNA_2_R1.fastq RNA-Seq 1.1 GB link
— CKO_RNA_3_R1.fastq RNA-Seq 1.1 GB link
— SRR11300801_GSM4409569 RNA-Seq 1.4 GB link
— SRR11300802_GSM4409570 RNA-Seq 1.3 GB link
— SRR11300803_GSM4409571 RNA-Seq 1.1 GB link
— SRR11300804_GSM4409572 RNA-Seq 1.4 GB link
— SRR11300805_GSM4409573 RNA-Seq 1.8 GB link
— SRR11300806_GSM4409574 RNA-Seq 1.2 GB link
— SRR11300807_GSM4409575 RNA-Seq 1.3 GB link
— SRR11300808_GSM4409576 RNA-Seq 1.1 GB link
— SRR11300809_GSM4409577 RNA-Seq 1.1 GB link
— WT_RNA_1_R1.fastq RNA-Seq 1.4 GB link
— WT_RNA_2_R1.fastq RNA-Seq 1.3 GB link
— WT_RNA_3_R1.fastq RNA-Seq 1.1 GB link