← All datasets

GSE157917

GSE GEO
View on GEO Export SRA CSV

Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS

Organism: Homo sapiens
Platform: GPL16791
Samples: 26
Experiment Types:
Expression profiling by high throughput sequencing Other
Submitted: Sep 14 2020
Last Updated: Jul 13 2021
Status: Public on Apr 13 2021
Contact: Alexis,A,Jourdain (Broad Institute of MIT & Harvard)

Relations

BioProject: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA663333 SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRP282348

Summary

Oxidative phosphorylation (OXPHOS) and glycolysis are the two major pathways for ATP production. The reliance on each varies across tissues and cell states, and can influence susceptibility to disease. At present, the full set ofmolecular mechanisms governing the relative expression and balance of these two pathways is unknown. Here, we focus on genes whose loss leads to an increase in OXPHOS activity. Unexpectedly, this class of genes is enriched for components of the pre-mRNA splicing machinery, in particular for subunits of the U1 snRNP. Among them, we show that LUC7L2 represses OXPHOS and promotes glycolysis by multiple mechanisms, including (1) splicing of the glycolytic enzyme PFKM to suppress glycogen synthesis, (2) splicing of the cystine/glutamate antiporter SLC7A11 (xCT) to suppress glutamate oxidation, and (3) secondary repression of mitochondrial respiratory supercomplex formation. Our results connect LUC7L2 expression and, more generally, the U1 snRNP to cellular energy metabolism.

Overall Design

RNA-Seq analysis of LUC7L2 WT HeLa and K562 grown in glucose or galactose, or LUC7L2 KO HeLa and K562 cells grown in glucose. eCLIP analysis of LUC7L2-interacting RNA in HeLa and K562 cells. Input and eCLIP are provided for each cell type in duplicate (total = 8 samples).

Analysis (3 steps)

View Data Processing
Processing steps for GSE157917
  1. The reads were aligned with STAR (Dobin et al., 2013) to the human genome hg19 using default parameters and a two-pass approach.
  2. Following a first pass alignment of each sample, novel splice junctions were pooled across all samples from the same cell type and incorporated into the genome annotation for a second pass alignment.
  3. Second pass gene counts derived from uniquely mapping pairs with the expected strandedness were output by STAR.

Supplementary Files (1)

GSE157917_RAW.tar Download
GEO Samples (26)
GSM4780786 GSM4780787 GSM4780788 GSM4780789 GSM4780790 GSM4780791 GSM4780792 GSM4780793 GSM4780794 GSM4780795 GSM4780796 GSM4780797 GSM4780798 GSM4780799 GSM4780800 GSM4780801 GSM4780802 GSM4780803 GSM4830581 GSM4830582 GSM4830583 GSM4830584 GSM4830585 GSM4830586 GSM4830587 GSM4830588

Dataset Citations (1)

Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS.
PMID 33852893 · 2021 · Molecular cell
Alexis A Jourdain, Bridget E Begg, Eran Mick, Hardik Shah, Sarah E Calvo, Owen S Skinner, Rohit Sharma, Steven M Blue, Gene W Yeo, Christopher B Burge, Vamsi K Mootha

SRA Experiments (26) and Runs (26)

Total: 27125 MB
SRX9120198 SRP282348 RNA-Seq PAIRED
GSM4780786: 10_HeLa_LUC7L2_WT_Glu; Homo sapiens; RNA-Seq
Sample: SRS7362735
BioProject: PRJNA663333
BioSample: SAMN16129595
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: HeLa cells
cell type: HeLa cells
genotype: LUC7L2 WT
culture condition: DMEM with 25mM glucose
Original files (1)
HeLa cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638141 51154558 10333220716 1234.73 10_HeLa_LUC7L2_WT_Glu.bam, SRR12638141, SRR12638141.lite SRA
SRX9120199 SRP282348 RNA-Seq PAIRED
GSM4780787: 12_HeLa_LUC7L2_WT_Glu; Homo sapiens; RNA-Seq
Sample: SRS7362736
BioProject: PRJNA663333
BioSample: SAMN16129590
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: HeLa cells
cell type: HeLa cells
genotype: LUC7L2 WT
culture condition: DMEM with 25mM glucose
Original files (1)
HeLa cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638142 51766610 10456855220 1256.81 12_HeLa_LUC7L2_WT_Glu.bam, SRR12638142, SRR12638142.lite SRA
SRX9120200 SRP282348 RNA-Seq PAIRED
GSM4780788: 04_HeLa_LUC7L2_WT_Glu_B; Homo sapiens; RNA-Seq
Sample: SRS7362737
BioProject: PRJNA663333
BioSample: SAMN16129589
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: HeLa cells
cell type: HeLa cells
genotype: LUC7L2 WT
culture condition: DMEM with 25mM glucose
Original files (1)
HeLa cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638143 108584808 21934131216 2562.69 04_HeLa_LUC7L2_WT_Glu_B.bam, SRR12638143, SRR12638143.lite SRA
SRX9120201 SRP282348 RNA-Seq PAIRED
GSM4780789: 13_HeLa_LUC7L2_WT_GAL; Homo sapiens; RNA-Seq
Sample: SRS7362738
BioProject: PRJNA663333
BioSample: SAMN16129588
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: HeLa cells
cell type: HeLa cells
genotype: LUC7L2 WT
culture condition: DMEM with 25mM galactose
Original files (1)
HeLa cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638144 47054541 9505017282 1189.4 13_HeLa_LUC7L2_WT_GAL.bam, SRR12638144, SRR12638144.lite SRA
SRX9120202 SRP282348 RNA-Seq PAIRED
GSM4780790: 14_HeLa_LUC7L2_WT_GAL; Homo sapiens; RNA-Seq
Sample: SRS7362739
BioProject: PRJNA663333
BioSample: SAMN16129587
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: HeLa cells
cell type: HeLa cells
genotype: LUC7L2 WT
culture condition: DMEM with 25mM galactose
Original files (1)
HeLa cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638145 44962428 9082410456 1090.8 14_HeLa_LUC7L2_WT_GAL.bam, SRR12638145, SRR12638145.lite SRA
SRX9120203 SRP282348 RNA-Seq PAIRED
GSM4780791: 15_HeLa_LUC7L2_WT_GAL; Homo sapiens; RNA-Seq
Sample: SRS7362740
BioProject: PRJNA663333
BioSample: SAMN16129615
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: HeLa cells
cell type: HeLa cells
genotype: LUC7L2 WT
culture condition: DMEM with 25mM galactose
Original files (1)
HeLa cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638146 46805800 9454771600 1106.99 15_HeLa_LUC7L2_WT_GAL.bam, SRR12638146, SRR12638146.lite SRA
SRX9120204 SRP282348 RNA-Seq PAIRED
GSM4780792: 16_HeLa_LUC7L2_KO_Glu; Homo sapiens; RNA-Seq
Sample: SRS7362741
BioProject: PRJNA663333
BioSample: SAMN16129593
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: HeLa cells
cell type: HeLa cells
genotype: LUC7L2 KO
culture condition: DMEM with 25mM glucose
Original files (1)
HeLa cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638147 44219825 8932404650 1092.02 16_HeLa_LUC7L2_KO_Glu.bam, SRR12638147, SRR12638147.lite SRA
SRX9120205 SRP282348 RNA-Seq PAIRED
GSM4780793: 17_HeLa_LUC7L2_KO_Glu; Homo sapiens; RNA-Seq
Sample: SRS7362742
BioProject: PRJNA663333
BioSample: SAMN16129592
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: HeLa cells
cell type: HeLa cells
genotype: LUC7L2 KO
culture condition: DMEM with 25mM glucose
Original files (1)
HeLa cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638148 56965470 11507024940 1384.93 17_HeLa_LUC7L2_KO_Glu.bam, SRR12638148, SRR12638148.lite SRA
SRX9120206 SRP282348 RNA-Seq PAIRED
GSM4780794: 18_HeLa_LUC7L2_KO_Glu; Homo sapiens; RNA-Seq
Sample: SRS7362743
BioProject: PRJNA663333
BioSample: SAMN16129591
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: HeLa cells
cell type: HeLa cells
genotype: LUC7L2 KO
culture condition: DMEM with 25mM glucose
Original files (1)
HeLa cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638149 51779161 10459390522 1231.91 18_HeLa_LUC7L2_KO_Glu.bam, SRR12638149, SRR12638149.lite SRA
SRX9120207 SRP282348 RNA-Seq PAIRED
GSM4780795: 02_K562_LUC7L2_WT_Glu; Homo sapiens; RNA-Seq
Sample: SRS7362744
BioProject: PRJNA663333
BioSample: SAMN16129614
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: K562 cells
cell type: K562 cells
genotype: LUC7L2 WT
culture condition: DMEM with 25mM glucose
Original files (1)
K562 cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638150 47367627 9568260654 1094.12 02_K562_LUC7L2_WT_Glu.bam, SRR12638150, SRR12638150.lite SRA
SRX9120208 SRP282348 RNA-Seq PAIRED
GSM4780796: 03_K562_LUC7L2_WT_Glu; Homo sapiens; RNA-Seq
Sample: SRS7362745
BioProject: PRJNA663333
BioSample: SAMN16129613
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: K562 cells
cell type: K562 cells
genotype: LUC7L2 WT
culture condition: DMEM with 25mM glucose
Original files (1)
K562 cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638151 50716905 10244814810 1186.67 03_K562_LUC7L2_WT_Glu.bam, SRR12638151, SRR12638151.lite SRA
SRX9120209 SRP282348 RNA-Seq PAIRED
GSM4780797: 04_K562_LUC7L2_WT_Glu_B; Homo sapiens; RNA-Seq
Sample: SRS7362746
BioProject: PRJNA663333
BioSample: SAMN16129612
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: K562 cells
cell type: K562 cells
genotype: LUC7L2 WT
culture condition: DMEM with 25mM glucose
Original files (1)
K562 cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638152 76417538 15436342676 1763.02 04_K562_LUC7L2_WT_Glu_B.bam, SRR12638152, SRR12638152.lite SRA
SRX9120210 SRP282348 RNA-Seq PAIRED
GSM4780798: 04_K562_LUC7L2_WT_GAL; Homo sapiens; RNA-Seq
Sample: SRS7362747
BioProject: PRJNA663333
BioSample: SAMN16129611
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: K562 cells
cell type: K562 cells
genotype: LUC7L2 WT
culture condition: DMEM with 25mM galactose
Original files (1)
K562 cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638153 51186933 10339760466 1210.35 04_K562_LUC7L2_WT_GAL.bam, SRR12638153, SRR12638153.lite SRA
SRX9120211 SRP282348 RNA-Seq PAIRED
GSM4780799: 05_K562_LUC7L2_WT_GAL; Homo sapiens; RNA-Seq
Sample: SRS7362748
BioProject: PRJNA663333
BioSample: SAMN16129610
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: K562 cells
cell type: K562 cells
genotype: LUC7L2 WT
culture condition: DMEM with 25mM galactose
Original files (1)
K562 cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638154 41314864 8345602528 958.61 05_K562_LUC7L2_WT_GAL.bam, SRR12638154, SRR12638154.lite SRA
SRX9120212 SRP282348 RNA-Seq PAIRED
GSM4780800: 06_K562_LUC7L2_WT_GAL; Homo sapiens; RNA-Seq
Sample: SRS7362749
BioProject: PRJNA663333
BioSample: SAMN16129609
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: K562 cells
cell type: K562 cells
genotype: LUC7L2 WT
culture condition: DMEM with 25mM galactose
Original files (1)
K562 cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638155 52863081 10678342362 1236.69 06_K562_LUC7L2_WT_GAL.bam, SRR12638155, SRR12638155.lite SRA
SRX9120213 SRP282348 RNA-Seq PAIRED
GSM4780801: 07_K562_LUC7L2_KO_Glu; Homo sapiens; RNA-Seq
Sample: SRS7362750
BioProject: PRJNA663333
BioSample: SAMN16129608
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: K562 cells
cell type: K562 cells
genotype: LUC7L2 KO
culture condition: DMEM with 25mM glucose
Original files (1)
K562 cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638156 49133841 9925035882 1117.46 07_K562_LUC7L2_KO_Glu.bam, SRR12638156, SRR12638156.lite SRA
SRX9120214 SRP282348 RNA-Seq PAIRED
GSM4780802: 08_K562_LUC7L2_KO_Glu; Homo sapiens; RNA-Seq
Sample: SRS7362751
BioProject: PRJNA663333
BioSample: SAMN16129607
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: K562 cells
cell type: K562 cells
genotype: LUC7L2 KO
culture condition: DMEM with 25mM glucose
Original files (1)
K562 cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638157 57506433 11616299466 1364.24 08_K562_LUC7L2_KO_Glu.bam, SRR12638157, SRR12638157.lite SRA
SRX9120215 SRP282348 RNA-Seq PAIRED
GSM4780803: 09_K562_LUC7L2_KO_Glu; Homo sapiens; RNA-Seq
Sample: SRS7362752
BioProject: PRJNA663333
BioSample: SAMN16129606
Platform: ILLUMINA
Instrument: Illumina NovaSeq 6000
Organism: Homo sapiens
Sample attributes
source_name: K562 cells
cell type: K562 cells
genotype: LUC7L2 KO
culture condition: DMEM with 25mM glucose
Original files (1)
K562 cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12638158 57906278 11697068156 1315.44 09_K562_LUC7L2_KO_Glu.bam, SRR12638158, SRR12638158.lite SRA
SRX9287174 SRP282348 RIP-Seq SINGLE
GSM4830581: input_HeLa_rep1; Homo sapiens; RIP-Seq
Sample: SRS7514597
BioProject: PRJNA663333
BioSample: SAMN16429994
Platform: ILLUMINA
Instrument: Illumina HiSeq 2500
Organism: Homo sapiens
Sample attributes
source_name: HeLa cells
cell type: HeLa cells
genotype: Wild-type
culture condition: DMEM with 25mM glucose
Original files (1)
HeLa cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12819255 12637895 960480020 340.72 LUC7L2_HeLa_INPUT1_S5_L008_R1_001.fastq.gz, SRR12819255, SRR12819255.… SRA
SRX9287175 SRP282348 RIP-Seq SINGLE
GSM4830582: input_HeLa_rep2; Homo sapiens; RIP-Seq
Sample: SRS7514598
BioProject: PRJNA663333
BioSample: SAMN16429993
Platform: ILLUMINA
Instrument: Illumina HiSeq 2500
Organism: Homo sapiens
Sample attributes
source_name: HeLa cells
cell type: HeLa cells
genotype: Wild-type
culture condition: DMEM with 25mM glucose
Original files (1)
HeLa cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12819256 9042972 687265872 245.25 LUC7L2_HeLa_INPUT2_S7_L008_R1_001.fastq.gz, SRR12819256, SRR12819256.… SRA
SRX9287176 SRP282348 RIP-Seq SINGLE
GSM4830583: input_K562_rep1; Homo sapiens; RIP-Seq
Sample: SRS7514599
BioProject: PRJNA663333
BioSample: SAMN16429992
Platform: ILLUMINA
Instrument: Illumina HiSeq 2500
Organism: Homo sapiens
Sample attributes
source_name: K562 cells
cell type: K562 cells
genotype: Wild-type
culture condition: DMEM with 25mM glucose
Original files (1)
K562 cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12819257 9531379 724384804 260.59 LUC7L2_K562_INPUT1_S1_L008_R1_001.fastq.gz, SRR12819257, SRR12819257.… SRA
SRX9287177 SRP282348 RIP-Seq SINGLE
GSM4830584: input_K562_rep2; Homo sapiens; RIP-Seq
Sample: SRS7514600
BioProject: PRJNA663333
BioSample: SAMN16429991
Platform: ILLUMINA
Instrument: Illumina HiSeq 2500
Organism: Homo sapiens
Sample attributes
source_name: K562 cells
cell type: K562 cells
genotype: Wild-type
culture condition: DMEM with 25mM glucose
Original files (1)
K562 cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12819258 8966929 681486604 244.58 LUC7L2_K562_INPUT2_S3_L008_R1_001.fastq.gz, SRR12819258, SRR12819258.… SRA
SRX9287178 SRP282348 RIP-Seq SINGLE
GSM4830585: eCLIP_HeLa_rep1; Homo sapiens; RIP-Seq
Sample: SRS7514601
BioProject: PRJNA663333
BioSample: SAMN16429990
Platform: ILLUMINA
Instrument: Illumina HiSeq 2500
Organism: Homo sapiens
Sample attributes
source_name: HeLa cells
cell type: HeLa cells
genotype: Wild-type
culture condition: DMEM with 25mM glucose
Original files (1)
HeLa cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12819259 23848997 1812523772 651.83 LUC7L2_HeLa_CLIP1_S6_L008_R1_001.fastq.gz, SRR12819259, SRR12819259.l… SRA
SRX9287179 SRP282348 RIP-Seq SINGLE
GSM4830586: eCLIP_HeLa_rep2; Homo sapiens; RIP-Seq
Sample: SRS7514602
BioProject: PRJNA663333
BioSample: SAMN16429989
Platform: ILLUMINA
Instrument: Illumina HiSeq 2500
Organism: Homo sapiens
Sample attributes
source_name: HeLa cells
cell type: HeLa cells
genotype: Wild-type
culture condition: DMEM with 25mM glucose
Original files (1)
HeLa cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12819260 22500304 1710023104 611.47 LUC7L2_HeLa_CLIP2_S8_L008_R1_001.fastq.gz, SRR12819260, SRR12819260.l… SRA
SRX9287180 SRP282348 RIP-Seq SINGLE
GSM4830587: eCLIP_K562_rep1; Homo sapiens; RIP-Seq
Sample: SRS7514603
BioProject: PRJNA663333
BioSample: SAMN16429988
Platform: ILLUMINA
Instrument: Illumina HiSeq 2500
Organism: Homo sapiens
Sample attributes
source_name: K562 cells
cell type: K562 cells
genotype: Wild-type
culture condition: DMEM with 25mM glucose
Original files (1)
K562 cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12819261 20176839 1533439764 560.09 LUC7L2_K562_CLIP1_S2_L008_R1_001.fastq.gz, SRR12819261, SRR12819261.l… SRA
SRX9287181 SRP282348 RIP-Seq SINGLE
GSM4830588: eCLIP_K562_rep2; Homo sapiens; RIP-Seq
Sample: SRS7514604
BioProject: PRJNA663333
BioSample: SAMN16429987
Platform: ILLUMINA
Instrument: Illumina HiSeq 2500
Organism: Homo sapiens
Sample attributes
source_name: K562 cells
cell type: K562 cells
genotype: Wild-type
culture condition: DMEM with 25mM glucose
Original files (1)
K562 cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12819262 29335841 2229523916 813.12 LUC7L2_K562_CLIP2_S4_L008_R1_001.fastq.gz, SRR12819262, SRR12819262.l… SRA

Linked Publications (1)

Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS.
Molecular cell · 2021

Data Files (26)

Accession File Name Stored Type Output Type Mapping Assembly Size Download
— LUC7L2_HeLa_CLIP1_S6_L008_R1_001.fastq.gz RIP-Seq 651.8 MB link
— LUC7L2_HeLa_CLIP2_S8_L008_R1_001.fastq.gz RIP-Seq 611.5 MB link
— LUC7L2_HeLa_INPUT1_S5_L008_R1_001.fastq.gz RIP-Seq 340.7 MB link
— LUC7L2_HeLa_INPUT2_S7_L008_R1_001.fastq.gz RIP-Seq 245.2 MB link
— LUC7L2_K562_CLIP1_S2_L008_R1_001.fastq.gz RIP-Seq 560.1 MB link
— LUC7L2_K562_CLIP2_S4_L008_R1_001.fastq.gz RIP-Seq 813.1 MB link
— LUC7L2_K562_INPUT1_S1_L008_R1_001.fastq.gz RIP-Seq 260.6 MB link
— LUC7L2_K562_INPUT2_S3_L008_R1_001.fastq.gz RIP-Seq 244.6 MB link
— 02_K562_LUC7L2_WT_Glu.bam RNA-Seq 1.1 GB link
— 03_K562_LUC7L2_WT_Glu.bam RNA-Seq 1.2 GB link
— 04_HeLa_LUC7L2_WT_Glu_B.bam RNA-Seq 2.5 GB link
— 04_K562_LUC7L2_WT_GAL.bam RNA-Seq 1.2 GB link
— 04_K562_LUC7L2_WT_Glu_B.bam RNA-Seq 1.7 GB link
— 05_K562_LUC7L2_WT_GAL.bam RNA-Seq 958.6 MB link
— 06_K562_LUC7L2_WT_GAL.bam RNA-Seq 1.2 GB link
— 07_K562_LUC7L2_KO_Glu.bam RNA-Seq 1.1 GB link
— 08_K562_LUC7L2_KO_Glu.bam RNA-Seq 1.3 GB link
— 09_K562_LUC7L2_KO_Glu.bam RNA-Seq 1.3 GB link
— 10_HeLa_LUC7L2_WT_Glu.bam RNA-Seq 1.2 GB link
— 12_HeLa_LUC7L2_WT_Glu.bam RNA-Seq 1.2 GB link
— 13_HeLa_LUC7L2_WT_GAL.bam RNA-Seq 1.2 GB link
— 14_HeLa_LUC7L2_WT_GAL.bam RNA-Seq 1.1 GB link
— 15_HeLa_LUC7L2_WT_GAL.bam RNA-Seq 1.1 GB link
— 16_HeLa_LUC7L2_KO_Glu.bam RNA-Seq 1.1 GB link
— 17_HeLa_LUC7L2_KO_Glu.bam RNA-Seq 1.4 GB link
— 18_HeLa_LUC7L2_KO_Glu.bam RNA-Seq 1.2 GB link