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GSE112479

GSE GEO
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The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells

Organism: Homo sapiens
Platform: GPL11154
Samples: 100
Experiment Types:
Expression profiling by high throughput sequencing Methylation profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing
Submitted: Mar 29 2018
Last Updated: Oct 20 2019
Status: Public on Oct 03 2019
Contact: Bruno,,Di Stefano (Baylor College of Medicine)

Relations

SuperSeries of: GSE112383 SuperSeries of: GSE112439 SuperSeries of: GSE112782 SuperSeries of: GSE124071 SuperSeries of: GSE124072 SuperSeries of: GSE125808 SuperSeries of: GSE125809 SuperSeries of: GSE125954 SuperSeries of: GSE134164 BioProject: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA448042

Summary

This SuperSeries is composed of the SubSeries listed below.

Overall Design

Refer to individual Series

Analysis (3 steps)

View Data Processing
Processing steps for GSE112479
  1. STAR was used to map sequencing reads to human reference genome (Ensembl annotation of hg19 assembly).
  2. Read counts over transcripts were calculated using HTSeq v.0.6.0 based on Ensembl annotation of hg19 genome.
  3. Differential expression analysis was performed using EdgeR.

Supplementary Files (1)

GSE112479_RAW.tar Download
GEO Samples (100)
GSM3069316 GSM3069317 GSM3069318 GSM3069319 GSM3069320 GSM3069321 GSM3069322 GSM3069323 GSM3069324 GSM3069325 GSM3069326 GSM3069327 GSM3069328 GSM3069329 GSM3069330 GSM3069331 GSM3069332 GSM3069333 GSM3070149 GSM3070150 GSM3083443 GSM3083444 GSM3083445 GSM3083446 GSM3083447 GSM3083448 GSM3083449 GSM3083450 GSM3083451 GSM3083452 GSM3520086 GSM3520087 GSM3520088 GSM3520089 GSM3520090 GSM3520091 GSM3520092 GSM3520093 GSM3520094 GSM3520095 GSM3520096 GSM3520097 GSM3520098 GSM3520099 GSM3520100 GSM3520101 GSM3582087 GSM3582088 GSM3582089 GSM3582090 GSM3582091 GSM3582092 GSM3582093 GSM3582094 GSM3582095 GSM3582096 GSM3582097 GSM3582098 GSM3582099 GSM3582100 GSM3582101 GSM3582102 GSM3582103 GSM3582104 GSM3582105 GSM3582106 GSM3582107 GSM3582108 GSM3582109 GSM3582110 GSM3582111 GSM3582112 GSM3582113 GSM3582114 GSM3582115 GSM3582116 GSM3582117 GSM3582118 GSM3582119 GSM3582120 GSM3582121 GSM3582122 GSM3582123 GSM3582124 GSM3582125 GSM3582126 GSM3585963 GSM3585964 GSM3585965 GSM3585966 GSM3585967 GSM3585968 GSM3938223 GSM3938224 GSM3938225 GSM3938226 GSM3938227 GSM3938228 GSM3938229 GSM3938230

Dataset Citations (1)

The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis.
PMID 31588046 · 2019 · Cell stem cell
Bruno Di Stefano, En-Ching Luo, Chuck Haggerty, Stefan Aigner, Jocelyn Charlton, Justin Brumbaugh, Fei Ji, Inés Rabano Jiménez, Katie J Clowers, Aaron J Huebner, Kendell Clement, Inna Lipchina, Marit A C de Kort, Anthony Anselmo, John Pulice, Mattia F M Gerli, Hongcang Gu, Steven P Gygi, Ruslan I Sadreyev, Alexander Meissner, Gene W Yeo, Konrad Hochedlinger

Linked Publications (1)

The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis.
Cell stem cell · 2019