GSE220845
GSE GEOProteomic discovery of chemical probes that perturb protein complexes in human cells II
Organism:
Homo sapiens
Platform:
GPL18573
Samples:
8
Experiment Types:
Expression profiling by high throughput sequencing
Other
Submitted:
Dec 13 2022
Last Updated:
Apr 13 2023
Status:
Public on Apr 13 2023
Contact:
Hsuan-Lin,,Her (UCSD)
Relations
BioProject: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA911743
Summary
Most proteins in the human proteome lack chemical probes, and several large-scale and generalizable small-molecule binding assays have been introduced to address this problem. How compounds discovered in such âbinding-firstâ assays affect protein function, nonetheless, often remains unclear. Here, we describe a âfunction firstâ proteomic strategy that uses size exclusion chromatography (SEC) to assess the global impact of electrophilic compounds on protein complexes in human cells. Integrating the SEC data with cysteine-directed activity-based profiling identifies changes in protein-protein interactions that are caused by site-specific liganding events, including the stereoselective engagement of cysteines in PSME1 and SF3B1 that disassemble the PA28 proteasome regulatory complex and remodel the spliceosome, respectively. Our findings thus show how multidimensional proteomic analysis of focused libraries of electrophilic compounds can expedite the discovery of chemical probes with site-specific functional effects on protein complexes in human cells. In this experiment, we probed the RNA-binding profile of DDX42 by eCLIP via an endogenously introduced HA-tag in the context of various SF3B1 ligands.
Overall Design
Three independent treatments were performed for each of 2x4 treatment groups (pre-treatment for 1h with 500nM dTAGv-1 or DMSO; followed by 8h of DMSO, 5uM WX-02-23, 5uM WX-02-43 or 10nM Pladienolide B), yielding a total of 24 samples.
Analysis (1 step)
View Data Processing
Processing steps for GSE220845
- For quantification of alternative RNA splicing, fastq files are adapter-trimmed by cutadapt 3.4 and aligned to GRCh38 by STAR 2.7 .6 and analyzed using rMATS (v4.1.1) (Shen et al., 2014) using the GENCODE (v35) GTF annotation for GRCh38 and the following parameters: -t paired --libType fr-unstranded âreadLength 150 --novelSS
Supplementary Files (280)
GSE220845_DMSO-DMSO_DMSO-PladB_A3SS.MATS.JC.txt.gz
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GSE220845_DMSO-DMSO_DMSO-PladB_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_DMSO-WX-2-43_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_DMSO-WX-2-43_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_DMSO-WX-2-43_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_DMSO-WX-2-43_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_DMSO-WX-2-43_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-DMSO_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-DMSO_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-DMSO_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-DMSO_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-DMSO_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-WX-2-23_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-WX-2-23_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-WX-2-23_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-WX-2-23_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-WX-2-23_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-WX-2-43_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-WX-2-43_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-WX-2-43_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-WX-2-43_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-PladB_dTAGv1-WX-2-43_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-DMSO_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-DMSO_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-DMSO_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-DMSO_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-DMSO_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-PladB_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-PladB_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-PladB_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-PladB_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-PladB_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-WX-2-23_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-WX-2-23_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-WX-2-23_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-WX-2-23_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-WX-2-23_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-WX-2-43_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-WX-2-43_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-WX-2-43_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-WX-2-43_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_DMSO-WX-2-43_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-DMSO_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-DMSO_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-DMSO_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-DMSO_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-DMSO_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-PladB_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-PladB_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-PladB_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-PladB_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-PladB_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-WX-2-43_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-WX-2-43_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-WX-2-43_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-WX-2-43_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-23_dTAGv1-WX-2-43_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-DMSO_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-DMSO_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-DMSO_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-DMSO_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-DMSO_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-PladB_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-PladB_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-PladB_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-PladB_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-PladB_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-WX-2-23_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-WX-2-23_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-WX-2-23_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-WX-2-23_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-WX-2-23_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-WX-2-43_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-WX-2-43_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-WX-2-43_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-WX-2-43_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_DMSO-WX-2-43_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-DMSO_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-DMSO_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-DMSO_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-DMSO_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-DMSO_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-PladB_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-PladB_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-PladB_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-PladB_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-PladB_SE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-WX-2-23_A3SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-WX-2-23_A5SS.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-WX-2-23_MXE.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-WX-2-23_RI.MATS.JC.txt.gz
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GSE220845_dTAGv1-WX-2-43_dTAGv1-WX-2-23_SE.MATS.JC.txt.gz
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GEO Samples (8)
SRA Experiments (8) and Runs (24)
Total: 212778 MBGSM6821347: DDX42-dTAG cells treated with 1h DMSO, 8h DMSO; Homo sapiens; RNA-Seq
Sample: SRS16114681
BioProject: PRJNA911743
BioSample: SAMN32192303
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Homo sapiens
Sample attributes
source_name: HCT116
cell type: HCT116 DDX42-dTAG
treatment: DMSO
Original files (1)
HCT116
Runs (3)
| Run | Spots | Bases | Size (MB) | Files | Link |
|---|---|---|---|---|---|
| SRR22709374 | 92646042 | 27793812600 | 8504.84 | MJ53-1C-DMSO-DMSO_R1_001.fastq.gz, MJ53-1C-DMSO-DMSO_R2_001.fastq.gz,… | SRA |
| SRR22709375 | 105488160 | 31646448000 | 9758.26 | MJ53-1A-DMSO-DMSO_R1_001.fastq.gz, MJ53-1A-DMSO-DMSO_R2_001.fastq.gz,… | SRA |
| SRR22709376 | 96223760 | 28867128000 | 8809.71 | MJ53-1B-DMSO-DMSO_R1_001.fastq.gz, MJ53-1B-DMSO-DMSO_R2_001.fastq.gz,… | SRA |
GSM6821348: DDX42-dTAG cells treated with 1h DMSO, 8h 10nM PladB; Homo sapiens; RNA-Seq
Sample: SRS16114682
BioProject: PRJNA911743
BioSample: SAMN32192302
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Homo sapiens
Sample attributes
source_name: HCT116
cell type: HCT116 DDX42-dTAG
treatment: Pladienolide B
Original files (1)
HCT116
Runs (3)
| Run | Spots | Bases | Size (MB) | Files | Link |
|---|---|---|---|---|---|
| SRR22709371 | 115118874 | 34535662200 | 10650.55 | MJ53-4C-DMSO-PladB_R1_001.fastq.gz, MJ53-4C-DMSO-PladB_R2_001.fastq.g… | SRA |
| SRR22709372 | 121238309 | 36371492700 | 11219.36 | MJ53-4A-DMSO-PladB_R1_001.fastq.gz, MJ53-4A-DMSO-PladB_R2_001.fastq.g… | SRA |
| SRR22709373 | 122790969 | 36837290700 | 11369.74 | MJ53-4B-DMSO-PladB_R1_001.fastq.gz, MJ53-4B-DMSO-PladB_R2_001.fastq.g… | SRA |
GSM6821349: DDX42-dTAG cells treated with 1h DMSO, 8h 5uM WX-02-23; Homo sapiens; RNA-Seq
Sample: SRS16114684
BioProject: PRJNA911743
BioSample: SAMN32192301
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Homo sapiens
Sample attributes
source_name: HCT116
cell type: HCT116 DDX42-dTAG
treatment: WX-02-23
Original files (1)
HCT116
Runs (3)
| Run | Spots | Bases | Size (MB) | Files | Link |
|---|---|---|---|---|---|
| SRR22709368 | 89222218 | 26766665400 | 8189.57 | MJ53-2C-DMSO-WX-2-23_R1_001.fastq.gz, MJ53-2C-DMSO-WX-2-23_R2_001.fas… | SRA |
| SRR22709369 | 87923961 | 26377188300 | 8073.97 | MJ53-2B-DMSO-WX-2-23_R1_001.fastq.gz, MJ53-2B-DMSO-WX-2-23_R2_001.fas… | SRA |
| SRR22709370 | 90274147 | 27082244100 | 8252.31 | MJ53-2A-DMSO-WX-2-23_R1_001.fastq.gz, MJ53-2A-DMSO-WX-2-23_R2_001.fas… | SRA |
GSM6821350: DDX42-dTAG cells treated with 1h DMSO, 8h 5uM WX-02-43; Homo sapiens; RNA-Seq
Sample: SRS16114683
BioProject: PRJNA911743
BioSample: SAMN32192300
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Homo sapiens
Sample attributes
source_name: HCT116
cell type: HCT116 DDX42-dTAG
treatment: WX-02-43
Original files (1)
HCT116
Runs (3)
| Run | Spots | Bases | Size (MB) | Files | Link |
|---|---|---|---|---|---|
| SRR22709365 | 123023584 | 36907075200 | 11218.55 | MJ53-3C-DMSO-WX-2-43_R1_001.fastq.gz, MJ53-3C-DMSO-WX-2-43_R2_001.fas… | SRA |
| SRR22709366 | 101870985 | 30561295500 | 9284.41 | MJ53-3B-DMSO-WX-2-43_R1_001.fastq.gz, MJ53-3B-DMSO-WX-2-43_R2_001.fas… | SRA |
| SRR22709367 | 98856092 | 29656827600 | 9051.25 | MJ53-3A-DMSO-WX-2-43_R1_001.fastq.gz, MJ53-3A-DMSO-WX-2-43_R2_001.fas… | SRA |
GSM6821351: DDX42-dTAG cells treated with 1h 500nM dTAGv-1, 8h DMSO; Homo sapiens; RNA-Seq
Sample: SRS16114685
BioProject: PRJNA911743
BioSample: SAMN32192299
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Homo sapiens
Sample attributes
source_name: HCT116
cell type: HCT116 DDX42-dTAG
treatment: DMSO
Original files (1)
HCT116
Runs (3)
| Run | Spots | Bases | Size (MB) | Files | Link |
|---|---|---|---|---|---|
| SRR22709362 | 129821419 | 38946425700 | 12044.19 | MJ53-5B-dTAGv1-DMSO_R1_001.fastq.gz, MJ53-5B-dTAGv1-DMSO_R2_001.fastq… | SRA |
| SRR22709363 | 118410856 | 35523256800 | 10940.16 | MJ53-5A-dTAGv1-DMSO_R1_001.fastq.gz, MJ53-5A-dTAGv1-DMSO_R2_001.fastq… | SRA |
| SRR22709364 | 109970227 | 32991068100 | 10170.75 | MJ53-5C-dTAGv1-DMSO_R1_001.fastq.gz, MJ53-5C-dTAGv1-DMSO_R2_001.fastq… | SRA |
GSM6821352: DDX42-dTAG cells treated with 1h 500nM dTAGv-1, 8h 10nM PladB; Homo sapiens; RNA-Seq
Sample: SRS16114686
BioProject: PRJNA911743
BioSample: SAMN32192298
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Homo sapiens
Sample attributes
source_name: HCT116
cell type: HCT116 DDX42-dTAG
treatment: Pladienolide B
Original files (1)
HCT116
Runs (3)
| Run | Spots | Bases | Size (MB) | Files | Link |
|---|---|---|---|---|---|
| SRR22709359 | 68833659 | 20650097700 | 6404.02 | MJ53-8A-dTAGv1-PladB_R1_001.fastq.gz, MJ53-8A-dTAGv1-PladB_R2_001.fas… | SRA |
| SRR22709360 | 72971499 | 21891449700 | 6737.07 | MJ53-8B-dTAGv1-PladB_R1_001.fastq.gz, MJ53-8B-dTAGv1-PladB_R2_001.fas… | SRA |
| SRR22709361 | 69969771 | 20990931300 | 6460.41 | MJ53-8C-dTAGv1-PladB_R1_001.fastq.gz, MJ53-8C-dTAGv1-PladB_R2_001.fas… | SRA |
GSM6821353: DDX42-dTAG cells treated with 1h 500nM dTAGv-1, 8h 5uM WX-02-23; Homo sapiens; RNA-Seq
Sample: SRS16114687
BioProject: PRJNA911743
BioSample: SAMN32192297
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Homo sapiens
Sample attributes
source_name: HCT116
cell type: HCT116 DDX42-dTAG
treatment: WX-02-23
Original files (1)
HCT116
Runs (3)
| Run | Spots | Bases | Size (MB) | Files | Link |
|---|---|---|---|---|---|
| SRR22709356 | 76836037 | 23050811100 | 7099.78 | MJ53-6B-dTAGv1-WX-2-23_R1_001.fastq.gz, MJ53-6B-dTAGv1-WX-2-23_R2_001… | SRA |
| SRR22709357 | 72791267 | 21837380100 | 6751.4 | MJ53-6C-dTAGv1-WX-2-23_R1_001.fastq.gz, MJ53-6C-dTAGv1-WX-2-23_R2_001… | SRA |
| SRR22709358 | 123266091 | 36979827300 | 11424.5 | MJ53-6A-dTAGv1-WX-2-23_R1_001.fastq.gz, MJ53-6A-dTAGv1-WX-2-23_R2_001… | SRA |
GSM6821354: DDX42-dTAG cells treated with 1h 500nM dTAGv-1, 8h 5uM WX-02-43; Homo sapiens; RNA-Seq
Sample: SRS16114688
BioProject: PRJNA911743
BioSample: SAMN32192296
Platform: ILLUMINA
Instrument: NextSeq 500
Organism: Homo sapiens
Sample attributes
source_name: HCT116
cell type: HCT116 DDX42-dTAG
treatment: WX-02-43
Original files (1)
HCT116
Runs (3)
| Run | Spots | Bases | Size (MB) | Files | Link |
|---|---|---|---|---|---|
| SRR22709353 | 78568124 | 23570437200 | 7273.59 | MJ53-7B-dTAGv1-WX-2-43_R1_001.fastq.gz, MJ53-7B-dTAGv1-WX-2-43_R2_001… | SRA |
| SRR22709354 | 74042000 | 22212600000 | 6862.92 | MJ53-7A-dTAGv1-WX-2-43_R1_001.fastq.gz, MJ53-7A-dTAGv1-WX-2-43_R2_001… | SRA |
| SRR22709355 | 67181038 | 20154311400 | 6226.4 | MJ53-7C-dTAGv1-WX-2-43_R1_001.fastq.gz, MJ53-7C-dTAGv1-WX-2-43_R2_001… | SRA |
Linked Publications (1)
Proteomic discovery of chemical probes that perturb protein complexes in human cells.
Molecular cell · 2023
Data Files (24)
| Accession | File Name | Stored Type | Output Type | Mapping Assembly | Size | Download | |
|---|---|---|---|---|---|---|---|
| — | MJ53-1A-DMSO-DMSO_R1_001.fastq.gz | RNA-Seq | 9.5 GB | link | |||
| — | MJ53-1B-DMSO-DMSO_R1_001.fastq.gz | RNA-Seq | 8.6 GB | link | |||
| — | MJ53-1C-DMSO-DMSO_R1_001.fastq.gz | RNA-Seq | 8.3 GB | link | |||
| — | MJ53-2A-DMSO-WX-2-23_R1_001.fastq.gz | RNA-Seq | 8.1 GB | link | |||
| — | MJ53-2B-DMSO-WX-2-23_R1_001.fastq.gz | RNA-Seq | 7.9 GB | link | |||
| — | MJ53-2C-DMSO-WX-2-23_R1_001.fastq.gz | RNA-Seq | 8.0 GB | link | |||
| — | MJ53-3A-DMSO-WX-2-43_R1_001.fastq.gz | RNA-Seq | 8.8 GB | link | |||
| — | MJ53-3B-DMSO-WX-2-43_R1_001.fastq.gz | RNA-Seq | 9.1 GB | link | |||
| — | MJ53-3C-DMSO-WX-2-43_R1_001.fastq.gz | RNA-Seq | 11.0 GB | link | |||
| — | MJ53-4A-DMSO-PladB_R1_001.fastq.gz | RNA-Seq | 11.0 GB | link | |||
| — | MJ53-4B-DMSO-PladB_R1_001.fastq.gz | RNA-Seq | 11.1 GB | link | |||
| — | MJ53-4C-DMSO-PladB_R1_001.fastq.gz | RNA-Seq | 10.4 GB | link | |||
| — | MJ53-5A-dTAGv1-DMSO_R1_001.fastq.gz | RNA-Seq | 10.7 GB | link | |||
| — | MJ53-5B-dTAGv1-DMSO_R1_001.fastq.gz | RNA-Seq | 11.8 GB | link | |||
| — | MJ53-5C-dTAGv1-DMSO_R1_001.fastq.gz | RNA-Seq | 9.9 GB | link | |||
| — | MJ53-6A-dTAGv1-WX-2-23_R1_001.fastq.gz | RNA-Seq | 11.2 GB | link | |||
| — | MJ53-6B-dTAGv1-WX-2-23_R1_001.fastq.gz | RNA-Seq | 6.9 GB | link | |||
| — | MJ53-6C-dTAGv1-WX-2-23_R1_001.fastq.gz | RNA-Seq | 6.6 GB | link | |||
| — | MJ53-7A-dTAGv1-WX-2-43_R1_001.fastq.gz | RNA-Seq | 6.7 GB | link | |||
| — | MJ53-7B-dTAGv1-WX-2-43_R1_001.fastq.gz | RNA-Seq | 7.1 GB | link | |||
| — | MJ53-7C-dTAGv1-WX-2-43_R1_001.fastq.gz | RNA-Seq | 6.1 GB | link | |||
| — | MJ53-8A-dTAGv1-PladB_R1_001.fastq.gz | RNA-Seq | 6.3 GB | link | |||
| — | MJ53-8B-dTAGv1-PladB_R1_001.fastq.gz | RNA-Seq | 6.6 GB | link | |||
| — | MJ53-8C-dTAGv1-PladB_R1_001.fastq.gz | RNA-Seq | 6.3 GB | link |