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GSE56504

GSE GEO
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Loss of nuclear TDP-43 in ALS causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurons

Organism: Mus musculus
Platform: GPL5188
Samples: 42
Experiment Types:
Expression profiling by array
Submitted: Apr 03 2014
Last Updated: Mar 03 2017
Status: Public on Jun 01 2014
Contact: Paul,Roy,Heath (University of Sheffield)

Relations

SuperSeries of: GSE33855 SuperSeries of: GSE56500 SuperSeries of: GSE56503 BioProject: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA243543

Summary

This SuperSeries is composed of the SubSeries listed below.

Overall Design

Refer to individual Series

Analysis (2 steps)

View Data Processing
Processing steps for GSE56504
  1. The Partek Genomics Suite was used to normalize (by GC RMA) and then analyse the microarray data following Affymetrix guidelines.
  2. Core probesets only were used.

Supplementary Files (1)

GSE56504_RAW.tar Download
GEO Samples (42)
GSM838032 GSM838033 GSM838034 GSM838035 GSM838036 GSM838037 GSM838038 GSM838039 GSM838040 GSM838041 GSM838042 GSM838043 GSM838044 GSM838045 GSM838046 GSM838047 GSM838048 GSM838049 GSM838050 GSM1362746 GSM1362747 GSM1362748 GSM1362749 GSM1362750 GSM1362751 GSM1362752 GSM1362753 GSM1362754 GSM1362755 GSM1362756 GSM1362757 GSM1362920 GSM1362921 GSM1362922 GSM1362923 GSM1362924 GSM1362925 GSM1362926 GSM1362927 GSM1362928 GSM1362929 GSM1362930

Dataset Citations (1)

PubMed citation (PMID 24750229)

Linked Publications (1)

Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis.
Acta neuropathologica · 2022