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GSE55727

GSE GEO
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Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage

Organism: Mus musculus
Platform: GPL9115
Samples: 24
Experiment Types:
Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing
Submitted: Mar 10 2014
Last Updated: May 15 2019
Status: Public on Apr 18 2015
Contact: Scott,T,Younger (Children's Mercy Kansas City)

Relations

BioProject: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA240784 SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRP039598

Summary

The tumor suppressor p53 has been studied extensively as a direct transcriptional activator of protein-coding genes. Recent studies, however, have shed light on novel regulatory functions of p53 within noncoding regions of the genome. Here, we use a systematic approach that integrates transcriptome-wide differential expression analysis, genome-wide p53 binding profiles, chromatin state maps, and additional genomic features to characterize the global regulatory roles of p53 in response to DNA damage in both human and mouse fibroblast models. In addition to known p53 targets, we identify many previously unappreciated mRNAs and long noncoding RNAs that are regulated by p53. Moreover, we find that p53 binding events occur predominantly within enhancer elements in both human and mouse systems. The ability to modulate enhancer activity offers an additional layer of complexity to the p53 network and greatly expands the diversity of genomic elements that are directly regulated by p53.

Overall Design

Human and Mouse fibroblasts cultured in the presence or absence of doxorubicin followed by RNA-Seq (Human:2 cell lines, each condition in duplicate; Mouse:MEF cell line,each condition in triplicate) and p53 ChIP-Seq (Human:2 cell lines, input and IP for each; Mouse:MEF cell line, input and IP)

Analysis (5 steps)

View Data Processing
Processing steps for GSE55727
  1. RNA-Seq Read Alignment: TopHat 2.0 with default options using UCSC known genes from hg19 or mm9 as reference transcriptome
  2. RNA-Seq Differential Expression: Cuffdiff 2.1 with default options using UCSC known genes from hg19 or mm9 as reference transcriptome
  3. ChIP-Seq Read Alignment: Bowtie 2.0 with default options using hg19 or mm9 as reference genome
  4. ChIP-Seq general peak calling: Scripture using hg19 or mm9 as reference genome
  5. ChIP-Seq significant peak calling: Cuffdiff 2.0 using Scripture output as peak reference

Supplementary Files (5)

GSE55727_Human_ChIP_peaks.bed.gz Download
GSE55727_Human_RNA_Expression_Matrix.txt.gz Download
GSE55727_MEF_ChIP_peaks.bed.gz Download
GSE55727_MEF_KO_RNA_Expression_Matrix.txt.gz Download
GSE55727_MEF_WT_RNA_Expression_Matrix.txt.gz Download
GEO Samples (24)
GSM1342483 GSM1342484 GSM1342485 GSM1342486 GSM1342487 GSM1342488 GSM1342489 GSM1342490 GSM1342491 GSM1342492 GSM1342493 GSM1342494 GSM1342495 GSM1342496 GSM1342497 GSM1342498 GSM1342499 GSM1342500 GSM1342501 GSM1342502 GSM1375967 GSM1375968 GSM1375969 GSM1375970

Dataset Citations (1)

PubMed citation (PMID 25883152)

SRA Experiments (24) and Runs (24)

Total: 93766 MB
SRX483580 SRP039598 RNA-Seq PAIRED
GSM1342483: GM06170_RNA_unt_rep1; Homo sapiens; RNA-Seq
Sample: SRS567899
BioProject: PRJNA240784
BioSample: SAMN02678377
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Homo sapiens
Sample attributes
source_name: Fetal skin fibroblasts
biomaterial_provider: Corriel Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM06170
treatment: None
cell line: GM06170
Original files (1)
Fetal skin fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186241 49929942 10085848284 6819.04 70-dox-rep1-forward.fq, SRR1186241, SRR1186241.sralite, 70-dox-rep1-r… SRA
SRX483581 SRP039598 RNA-Seq PAIRED
GSM1342484: GM06170_RNA_unt_rep2; Homo sapiens; RNA-Seq
Sample: SRS567900
BioProject: PRJNA240784
BioSample: SAMN02678381
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Homo sapiens
Sample attributes
source_name: Fetal skin fibroblasts
biomaterial_provider: Corriel Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM06170
treatment: None
cell line: GM06170
Original files (1)
Fetal skin fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186242 34681122 7005586644 4719.74 SRR1186242, SRR1186242.sralite, 70-dox-rep2-reverse.fq, 70-dox-rep2-f… SRA
SRX483582 SRP039598 RNA-Seq PAIRED
GSM1342485: GM06170_RNA_dox_rep1; Homo sapiens; RNA-Seq
Sample: SRS567901
BioProject: PRJNA240784
BioSample: SAMN02678379
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Homo sapiens
Sample attributes
source_name: Fetal skin fibroblasts
biomaterial_provider: Corriel Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM06170
treatment: 0.2 ug/ml Doxorubicin 12 hours
cell line: GM06170
Original files (1)
Fetal skin fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186243 32666366 6598605932 4439.55 70+dox-rep1-forward.fq, SRR1186243, SRR1186243.sralite, 70+dox-rep1-r… SRA
SRX483583 SRP039598 RNA-Seq PAIRED
GSM1342486: GM06170_RNA_dox_rep2; Homo sapiens; RNA-Seq
Sample: SRS567902
BioProject: PRJNA240784
BioSample: SAMN02678378
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Homo sapiens
Sample attributes
source_name: Fetal skin fibroblasts
biomaterial_provider: Corriel Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM06170
treatment: 0.2 ug/ml Doxorubicin 12 hours
cell line: GM06170
Original files (1)
Fetal skin fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186244 33749060 6817310120 4591.38 SRR1186244, SRR1186244.sralite, 70+dox-rep2-reverse.fq, 70+dox-rep2-f… SRA
SRX483584 SRP039598 ChIP-Seq SINGLE
GSM1342487: GM06170_ChIP_input; Homo sapiens; ChIP-Seq
Sample: SRS567903
BioProject: PRJNA240784
BioSample: SAMN02678380
Platform: ILLUMINA
Instrument: Illumina Genome Analyzer II
Organism: Homo sapiens
Sample attributes
source_name: Fetal skin fibroblasts
biomaterial_provider: Corriel Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM06170
chip antibody: input
treatment: 0.2 ug/ml Doxorubicin 12 hours
cell line: GM06170
Original files (1)
Fetal skin fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186245 19292849 694542564 471.22 SRR1186245, GM06170_input.fastq SRA
SRX483585 SRP039598 ChIP-Seq SINGLE
GSM1342488: GM06170_ChIP_p53; Homo sapiens; ChIP-Seq
Sample: SRS567904
BioProject: PRJNA240784
BioSample: SAMN02678383
Platform: ILLUMINA
Instrument: Illumina Genome Analyzer II
Organism: Homo sapiens
Sample attributes
source_name: Fetal skin fibroblasts
biomaterial_provider: Corriel Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM06170
chip antibody: p53
treatment: 0.2 ug/ml Doxorubicin 12 hours
cell line: GM06170
Original files (1)
Fetal skin fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186246 20886529 751915044 348.01 SRR1186246, GM06170_ChIP.fastq SRA
SRX483586 SRP039598 RNA-Seq PAIRED
GSM1342489: GM00011_RNA_unt_rep1; Homo sapiens; RNA-Seq
Sample: SRS567905
BioProject: PRJNA240784
BioSample: SAMN02678382
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Homo sapiens
Sample attributes
source_name: Fetal skin fibroblasts
biomaterial_provider: Corriel Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM00011
treatment: None
cell line: GM00011
Original files (1)
Fetal skin fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186247 33277175 6721989350 4742.47 11-dox-rep1-forward.fq, 11-dox-rep1-reverse.fq, SRR1186247, SRR118624… SRA
SRX483587 SRP039598 RNA-Seq PAIRED
GSM1342490: GM00011_RNA_unt_rep2; Homo sapiens; RNA-Seq
Sample: SRS567906
BioProject: PRJNA240784
BioSample: SAMN02678386
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Homo sapiens
Sample attributes
source_name: Fetal skin fibroblasts
biomaterial_provider: Corriel Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM00011
treatment: None
cell line: GM00011
Original files (1)
Fetal skin fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186248 38587682 7794711764 5487.87 11-dox-rep2-forward.fq, SRR1186248, SRR1186248.sralite, 11-dox-rep2-r… SRA
SRX483588 SRP039598 RNA-Seq PAIRED
GSM1342491: GM00011_RNA_dox_rep1; Homo sapiens; RNA-Seq
Sample: SRS567907
BioProject: PRJNA240784
BioSample: SAMN02678385
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Homo sapiens
Sample attributes
source_name: Fetal skin fibroblasts
biomaterial_provider: Corriel Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM00011
treatment: 0.2 ug/ml Doxorubicin 12 hours
cell line: GM00011
Original files (1)
Fetal skin fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186249 35879446 7247648092 5112.12 11+dox-rep1-reverse.fq, SRR1186249, SRR1186249.sralite, 11+dox-rep1-f… SRA
SRX483589 SRP039598 RNA-Seq PAIRED
GSM1342492: GM00011_RNA_dox_rep2; Homo sapiens; RNA-Seq
Sample: SRS567908
BioProject: PRJNA240784
BioSample: SAMN02678384
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Homo sapiens
Sample attributes
source_name: Fetal skin fibroblasts
biomaterial_provider: Corriel Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM00011
treatment: 0.2 ug/ml Doxorubicin 12 hours
cell line: GM00011
Original files (1)
Fetal skin fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186250 41968719 8477681238 5985.28 SRR1186250, SRR1186250.sralite, 11+dox-rep2-reverse.fq, 11+dox-rep2-f… SRA
SRX483590 SRP039598 ChIP-Seq SINGLE
GSM1342493: GM00011_ChIP_input; Homo sapiens; ChIP-Seq
Sample: SRS567909
BioProject: PRJNA240784
BioSample: SAMN02678387
Platform: ILLUMINA
Instrument: Illumina Genome Analyzer II
Organism: Homo sapiens
Sample attributes
source_name: Fetal skin fibroblasts
biomaterial_provider: Corriel Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM00011
chip antibody: input
treatment: 0.2 ug/ml Doxorubicin 12 hours
cell line: GM00011
Original files (1)
Fetal skin fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186251 21135861 760890996 508.33 SRR1186251, GM00011_input.fastq SRA
SRX483591 SRP039598 ChIP-Seq SINGLE
GSM1342494: GM00011_ChIP_p53; Homo sapiens; ChIP-Seq
Sample: SRS567910
BioProject: PRJNA240784
BioSample: SAMN02678388
Platform: ILLUMINA
Instrument: Illumina Genome Analyzer II
Organism: Homo sapiens
Sample attributes
source_name: Fetal skin fibroblasts
biomaterial_provider: Corriel Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM00011
chip antibody: p53
treatment: 0.2 ug/ml Doxorubicin 12 hours
cell line: GM00011
Original files (1)
Fetal skin fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186252 31710642 1141583112 629.09 GM00011_ChIP.fastq, SRR1186252 SRA
SRX483592 SRP039598 RNA-Seq PAIRED
GSM1342495: MEF_WT_RNA_unt_rep1; Mus musculus; RNA-Seq
Sample: SRS567911
BioProject: PRJNA240784
BioSample: SAMN02678389
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Mus musculus
Sample attributes
source_name: Mouse embryonic fibroblasts
treatment: None
cell line: MEF-1
Original files (1)
Mouse embryonic fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186253 30879381 6237634962 4286.6 SRR1186253, SRR1186253.sralite, WT_UNT_Rep1-reverse.fq, WT_UNT_Rep1-f… SRA
SRX483593 SRP039598 RNA-Seq PAIRED
GSM1342496: MEF_WT_RNA_unt_rep2; Mus musculus; RNA-Seq
Sample: SRS567912
BioProject: PRJNA240784
BioSample: SAMN02678390
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Mus musculus
Sample attributes
source_name: Mouse embryonic fibroblasts
treatment: None
cell line: MEF-1
Original files (1)
Mouse embryonic fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186254 36915503 7456931606 5115.4 WT_UNT_Rep2-reverse.fq, SRR1186254, SRR1186254.sralite, WT_UNT_Rep2-f… SRA
SRX483594 SRP039598 RNA-Seq PAIRED
GSM1342497: MEF_WT_RNA_unt_rep3; Mus musculus; RNA-Seq
Sample: SRS567913
BioProject: PRJNA240784
BioSample: SAMN02678392
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Mus musculus
Sample attributes
source_name: Mouse embryonic fibroblasts
treatment: None
cell line: MEF-1
Original files (1)
Mouse embryonic fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186255 35193063 7108998726 4909.09 WT_UNT_Rep3-reverse.fq, SRR1186255, SRR1186255.sralite, WT_UNT_Rep3-f… SRA
SRX483595 SRP039598 RNA-Seq PAIRED
GSM1342498: MEF_WT_RNA_dox_rep1; Mus musculus; RNA-Seq
Sample: SRS567914
BioProject: PRJNA240784
BioSample: SAMN02678391
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Mus musculus
Sample attributes
source_name: Mouse embryonic fibroblasts
treatment: 0.2 ug/ml Doxorubicin 12 hours
cell line: MEF-1
Original files (1)
Mouse embryonic fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186256 32486136 6562199472 4499.46 WT_DOX_Rep1-reverse.fq, SRR1186256.sralite, SRR1186256, WT_DOX_Rep1-f… SRA
SRX483596 SRP039598 RNA-Seq PAIRED
GSM1342499: MEF_WT_RNA_dox_rep2; Mus musculus; RNA-Seq
Sample: SRS567915
BioProject: PRJNA240784
BioSample: SAMN02678393
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Mus musculus
Sample attributes
source_name: Mouse embryonic fibroblasts
treatment: 0.2 ug/ml Doxorubicin 12 hours
cell line: MEF-1
Original files (1)
Mouse embryonic fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186257 42942248 8674334096 5975.7 SRR1186257, SRR1186257.sralite, WT_DOX_Rep2-reverse.fq, WT_DOX_Rep2-f… SRA
SRX483597 SRP039598 RNA-Seq PAIRED
GSM1342500: MEF_WT_RNA_dox_rep3; Mus musculus; RNA-Seq
Sample: SRS567916
BioProject: PRJNA240784
BioSample: SAMN02678395
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Mus musculus
Sample attributes
source_name: Mouse embryonic fibroblasts
treatment: 0.2 ug/ml Doxorubicin 12 hours
cell line: MEF-1
Original files (1)
Mouse embryonic fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186258 35701871 7211777942 4965.5 WT_DOX_Rep3-forward.fq, WT_DOX_Rep3-reverse.fq, SRR1186258.sralite, S… SRA
SRX483598 SRP039598 ChIP-Seq SINGLE
GSM1342501: MEF_ChIP_input; Mus musculus; ChIP-Seq
Sample: SRS567917
BioProject: PRJNA240784
BioSample: SAMN02678394
Platform: ILLUMINA
Instrument: Illumina Genome Analyzer II
Organism: Mus musculus
Sample attributes
source_name: Mouse embryonic fibroblasts
chip antibody: input
treatment: 0.2 ug/ml Doxorubicin 12 hours
cell line: MEF-1
Original files (1)
Mouse embryonic fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186259 16016755 576603180 281.6 MEF_input.fastq, SRR1186259 SRA
SRX483599 SRP039598 ChIP-Seq SINGLE
GSM1342502: MEF_ChIP_p53; Mus musculus; ChIP-Seq
Sample: SRS567918
BioProject: PRJNA240784
BioSample: SAMN02678396
Platform: ILLUMINA
Instrument: Illumina Genome Analyzer II
Organism: Mus musculus
Sample attributes
source_name: Mouse embryonic fibroblasts
chip antibody: p53
treatment: 0.2 ug/ml Doxorubicin 12 hours
cell line: MEF-1
Original files (1)
Mouse embryonic fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1186260 16685745 600686820 299.46 MEF_ChIP.fastq, SRR1186260 SRA
SRX529161 SRP039598 RNA-Seq PAIRED
GSM1375967: MEF_KO_RNA_unt_rep1; Mus musculus; RNA-Seq
Sample: SRS598858
BioProject: PRJNA240784
BioSample: SAMN02740901
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Mus musculus
Sample attributes
source_name: Mouse embryonic fibroblasts
treatment: None
genotype/variation: p53 -/-
Original files (1)
Mouse embryonic fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1265767 37973552 7670657504 5290.71 KO_UNT_Rep1-forward.fq.gz, KO_UNT_Rep1-reverse.fq.gz, SRR1265767.sral… SRA
SRX529162 SRP039598 RNA-Seq PAIRED
GSM1375968: MEF_KO_RNA_unt_rep2; Mus musculus; RNA-Seq
Sample: SRS598859
BioProject: PRJNA240784
BioSample: SAMN02740902
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Mus musculus
Sample attributes
source_name: Mouse embryonic fibroblasts
treatment: None
genotype/variation: p53 -/-
Original files (1)
Mouse embryonic fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1265768 35584654 7188100108 4973.96 KO_UNT_Rep2-reverse.fq.gz, SRR1265768, SRR1265768.sralite, KO_UNT_Rep… SRA
SRX529163 SRP039598 RNA-Seq PAIRED
GSM1375969: MEF_KO_RNA_dox_rep1; Mus musculus; RNA-Seq
Sample: SRS598860
BioProject: PRJNA240784
BioSample: SAMN02740903
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Mus musculus
Sample attributes
source_name: Mouse embryonic fibroblasts
treatment: 0.2 ug/ml Doxorubicin 6 hours
genotype/variation: p53 -/-
Original files (1)
Mouse embryonic fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1265769 36356076 7343927352 5049.04 KO_DOX_Rep1-forward.fq.gz, SRR1265769, SRR1265769.sralite, KO_DOX_Rep… SRA
SRX529164 SRP039598 RNA-Seq PAIRED
GSM1375970: MEF_KO_RNA_dox_rep2; Mus musculus; RNA-Seq
Sample: SRS598861
BioProject: PRJNA240784
BioSample: SAMN02740900
Platform: ILLUMINA
Instrument: Illumina HiSeq 2000
Organism: Mus musculus
Sample attributes
source_name: Mouse embryonic fibroblasts
treatment: 0.2 ug/ml Doxorubicin 6 hours
genotype/variation: p53 -/-
Original files (1)
Mouse embryonic fibroblasts
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR1265770 30649905 6191280810 4265.06 SRR1265770.sralite, SRR1265770, KO_DOX_Rep2-reverse.fq.gz, KO_DOX_Rep… SRA

Linked Publications (1)

Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program.
Molecular cell · 2020

Data Files (24)

Accession File Name Stored Type Output Type Mapping Assembly Size Download
— GM00011_ChIP.fastq ChIP-Seq 629.1 MB link
— MEF_ChIP.fastq ChIP-Seq 299.5 MB link
— MEF_input.fastq ChIP-Seq 281.6 MB link
— SRR1186245 ChIP-Seq 471.2 MB link
— SRR1186246 ChIP-Seq 348.0 MB link
— SRR1186251 ChIP-Seq 508.3 MB link
— 11-dox-rep1-forward.fq RNA-Seq 4.6 GB link
— 11+dox-rep1-reverse.fq RNA-Seq 5.0 GB link
— 11-dox-rep2-forward.fq RNA-Seq 5.4 GB link
— 70-dox-rep1-forward.fq RNA-Seq 6.7 GB link
— 70+dox-rep1-forward.fq RNA-Seq 4.3 GB link
— KO_DOX_Rep1-forward.fq.gz RNA-Seq 4.9 GB link
— KO_UNT_Rep1-forward.fq.gz RNA-Seq 5.2 GB link
— KO_UNT_Rep2-reverse.fq.gz RNA-Seq 4.9 GB link
— SRR1186242 RNA-Seq 4.6 GB link
— SRR1186244 RNA-Seq 4.5 GB link
— SRR1186250 RNA-Seq 5.8 GB link
— SRR1186253 RNA-Seq 4.2 GB link
— SRR1186257 RNA-Seq 5.8 GB link
— SRR1265770.sralite RNA-Seq 4.2 GB link
— WT_DOX_Rep1-reverse.fq RNA-Seq 4.4 GB link
— WT_DOX_Rep3-forward.fq RNA-Seq 4.8 GB link
— WT_UNT_Rep2-reverse.fq RNA-Seq 5.0 GB link
— WT_UNT_Rep3-reverse.fq RNA-Seq 4.8 GB link