#!/usr/bin/env bash
# Bulk download script for GSE302649
# Generated from Yeo Lab Knowledgebase
# Total files: 5

OUTDIR=GSE302649
mkdir -p "$OUTDIR"
cd "$OUTDIR"

# --- GEO supplementary files ---
wget -nc ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE302nnn/GSE302649/suppl/GSE302649_RAW.tar -O GSE302649_RAW.tar

# --- SRA run files ---
# Tip: use 'fasterq-dump' from SRA Toolkit for FASTQ conversion
#      with optional renaming to original submitted FASTQ names.
# Set to 1 to rename SRR outputs (e.g. SRR_1.fastq.gz -> sample_R1.fastq.gz)
RENAME_SRA_TO_ORIGINAL=1

_compress_if_exists() {
  local stem="$1"
  if [ -f "${stem}.fastq" ]; then
    gzip -f "${stem}.fastq"
    echo "${stem}.fastq.gz"
    return 0
  fi
  if [ -f "${stem}.fq" ]; then
    gzip -f "${stem}.fq"
    echo "${stem}.fq.gz"
    return 0
  fi
  return 1
}

# Option A: Download via SRA Toolkit (recommended)
fasterq-dump --split-files SRR34562255
gz1="$(_compress_if_exists SRR34562255_1 || true)"
gz2="$(_compress_if_exists SRR34562255_2 || true)"
gzs="$(_compress_if_exists SRR34562255 || true)"

fasterq-dump --split-files SRR34562256
gz1="$(_compress_if_exists SRR34562256_1 || true)"
gz2="$(_compress_if_exists SRR34562256_2 || true)"
gzs="$(_compress_if_exists SRR34562256 || true)"


# Option B: Direct download (larger .sra files)
curl -L -O -C - https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos9/sra-pub-zq-924/SRR034/34562/SRR34562255/SRR34562255.lite.1
curl -L -O -C - https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos9/sra-pub-zq-924/SRR034/34562/SRR34562256/SRR34562256.lite.1

# --- Additional data files ---
curl -L -O -C - https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos9/sra-pub-zq-924/SRR034/34562/SRR34562255/SRR34562255.lite.1
curl -L -O -C - https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos9/sra-pub-zq-924/SRR034/34562/SRR34562256/SRR34562256.lite.1

echo "Download complete. Files saved to $OUTDIR"