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  1. Human CCR4 deadenylase homolog Angel1 is a non-stop mRNA decay factor.

    RNA (New York, N.Y.) · 2025 · 31(8): 1195-1205

    Translation elongation stalls trigger mRNA decay and degradation of the nascent polypeptide via translation-dependent quality control pathways. One such pathway, non-stop mRNA decay (NSD), targets aberrant mRNAs that lack stop codons, for example, due to premature polyadenylation. Here we identify …

    PMID 40441874 DOI ↗

Datasets 1

GSE199650 GSE · GEO

The 2',3' cyclic phosphatase Angel1 facilitates mRNA degradation during human ribosome-associated quality control

Homo sapiens · GPL15520

Analyses 1

GSE199650 Processing Pipeline

GSE199650 · 11 steps · RIP-Seq · code_examples

Human CCR4 deadenylase homolog Angel1 is a non-stop mRNA decay factor. (2025)