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2 results for “DDX3X”
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Integrated multi-omic characterizations of the synapse reveal RNA processing factors and ubiquitin ligases associated with neurodevelopmental disorders.
Cell systems · 2025 · 16(4): 101204
The molecular composition of the excitatory synapse is incompletely defined due to its dynamic nature across developmental stages and neuronal populations. To address this gap, we apply proteomic mass spectrometry to characterize the synapse in multiple biological models, including the …
PMID 40054464 DOI ↗
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Systematic Discovery of RNA Binding Proteins that Regulate MicroRNA Levels.
Molecular cell · 2018 · 69(6): 1005-1016.e7
RNA binding proteins (RBPs) interact with primary, precursor, and mature microRNAs (miRs) to influence mature miR levels, which in turn affect critical aspects of human development and disease. To understand how RBPs contribute to miR biogenesis, we analyzed human enhanced …
PMID 29547715 DOI ↗
Datasets 7
shRNA knockdown against DDX3X in HepG2 cells followed by RNA-seq. (DDX3X-BGHLV12)
Homo sapiens
shRNA knockdown against DDX3X in K562 cells followed by RNA-seq. (DDX3X-LV08)
Homo sapiens
Integrated proteomic and multi-mic characterizations of the synapse reveal RNA processing factor and ubiquitin ligases associated with neurodevelopment disorders
Homo sapiens · GPL24676
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