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1 result for “FAS”
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Engineered U1 snRNAs to modulate alternatively spliced exons.
Methods (San Diego, Calif.) · 2022 · 205: 140-148
Alternative splicing accounts for a considerable portion of transcriptomic diversity, as most protein-coding genes are spliced into multiple mRNA isoforms. However, errors in splicing patterns can give rise to mis-splicing with pathological consequences, such as the congenital diseases familial dysautonomia, …
PMID 35764245 DOI ↗
Datasets 12
shRNA knockdown against FASTKD2 in K562 cells followed by RNA-seq. (FASTKD2 BGKLV13)
Homo sapiens
shRNA knockdown against FASTKD2 in HepG2 cells followed by RNA-seq. (FASTKD2 BGHLV14)
Homo sapiens
RNA-seq on HepG2 cells treated with an shRNA knockdown against FASTKD1. (FASTKD1-BGHLV22)
Homo sapiens
Active ribosome profiling with RiboLace and standard ribosome profiling in HEK-293 cells
Homo sapiens · GPL16791
Transcriptomic profiles of muscular dystrophy with myositis (mdm) in extensor digitorum longus, psoas, and soleus muscles from mice
Mus musculus · GPL19057
RNA-seq of metformin treatment in liver in WT, Raptor Ser-Ala mutant, Tsc2-null, Raptor mutant;Tsc2-null, and Ampk-null
Mus musculus · GPL24247
FLARE: A fast and flexible peak-calling pipeline for identifying RNA editing foci
Homo sapiens · GPL24676
Skipper analysis of RNA-protein interactions highlights depletion of genetic variation in translation factor binding sites
Homo sapiens · GPL24676
Analyses 1
GSE215252 · 5 steps · RNA-Seq · code_examples
FLARE: a fast and flexible workflow for identifying RNA editing foci. (2023)