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4 results for “Immediate early genes”
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Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus.
Neurobiology of disease · 2022 · 172: 105834
Synapse dysfunction and loss are central features of neurodegenerative diseases, caused in part by the accumulation of protein oligomers. Amyloid-β, tau, prion, and α-synuclein oligomers bind to the cellular prion protein (PrP<sup>C),</sup> resulting in the activation of macromolecular complexes and …
PMID 35905927 DOI ↗
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Emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States.
Cell · 2021 · 184(10): 2587-2594.e7
The highly transmissible B.1.1.7 variant of SARS-CoV-2, first identified in the United Kingdom, has gained a foothold across the world. Using S gene target failure (SGTF) and SARS-CoV-2 genomic sequencing, we investigated the prevalence and dynamics of this variant in …
PMID 33861950 DOI ↗
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Genomic epidemiology identifies emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States.
medRxiv : the preprint server for health sciences · 2021
As of January of 2021, the highly transmissible B.1.1.7 variant of SARS-CoV-2, which was first identified in the United Kingdom (U.K.), has gained a strong foothold across the world. Because of the sudden and rapid rise of B.1.1.7, we investigated …
PMID 33564780 DOI ↗
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Human cytomegalovirus infection of human embryonic stem cell-derived primitive neural stem cells is restricted at several steps but leads to the persistence of viral DNA.
Journal of virology · 2014 · 88(8): 4021-39
Congenital human cytomegalovirus (HCMV) infection is a major cause of central nervous system structural anomalies and sensory impairments. It is likely that the stage of fetal development, as well as the state of differentiation of susceptible cells at the time …
PMID 24453373 DOI ↗
Datasets 1
Prions induce an early Arc response in the hippocampus of prion-infected mice
Mus musculus · GPL21103
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