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5 results for “Period”

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  1. Transcriptome regulation by PARP13 in basal and antiviral states in human cells.

    iScience · 2024 · 27(4): 109251

    The RNA-binding protein PARP13 is a primary factor in the innate antiviral response, which suppresses translation and drives decay of bound viral and host RNA. PARP13 interacts with many proteins encoded by interferon-stimulated genes (ISG) to activate antiviral pathways including …

    PMID 38495826 DOI ↗

  2. Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus.

    Neurobiology of disease · 2022 · 172: 105834

    Synapse dysfunction and loss are central features of neurodegenerative diseases, caused in part by the accumulation of protein oligomers. Amyloid-β, tau, prion, and α-synuclein oligomers bind to the cellular prion protein (PrP<sup>C),</sup> resulting in the activation of macromolecular complexes and …

    PMID 35905927 DOI ↗

  3. Implementation of Practical Surface SARS-CoV-2 Surveillance in School Settings.

    mSystems · 2022 · 7(4): e0010322

    Surface sampling for SARS-CoV-2 RNA detection has shown considerable promise to detect exposure of built environments to infected individuals shedding virus who would not otherwise be detected. Here, we compare two popular sampling media (VTM and SDS) and two popular …

    PMID 35703437 DOI ↗

  4. Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development.

    Cell stem cell · 2019 · 25(4): 558-569.e7

    Structural and transcriptional changes during early brain maturation follow fixed developmental programs defined by genetics. However, whether this is true for functional network activity remains unknown, primarily due to experimental inaccessibility of the initial stages of the living human brain. …

    PMID 31474560 DOI ↗

  5. The Period protein homolog LIN-42 negatively regulates microRNA biogenesis in C. elegans.

    Developmental biology · 2014 · 390(2): 126-35

    MicroRNAs (miRNAs) are small RNAs that post-transcriptionally regulate gene expression in many multicellular organisms. They are encoded in the genome and transcribed into primary (pri-) miRNAs before two processing steps that ultimately produce the mature miRNA. In order to generate …

    PMID 24699545 DOI ↗

Datasets 2

GSE237099 GSE · GEO

Analysis of skeletal muscle gene expression upon mouse hindlimb unloading and reloading

Mus musculus · GPL13112

GSE86479 GSE · GEO

Pseudotemporal ordering of single cells reveals metabolic control of postnatal beta cell proliferation

Mus musculus · GPL17021

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