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  1. Engineered U1 snRNAs to modulate alternatively spliced exons.

    Methods (San Diego, Calif.) · 2022 · 205: 140-148

    Alternative splicing accounts for a considerable portion of transcriptomic diversity, as most protein-coding genes are spliced into multiple mRNA isoforms. However, errors in splicing patterns can give rise to mis-splicing with pathological consequences, such as the congenital diseases familial dysautonomia, …

    PMID 35764245 DOI ↗

Datasets 2

ENCSR090UMI ENCSR · ENCODE

shRNA knockdown against SMN1 in HepG2 cells followed by RNA-seq. (SMN1-BGHLV20)

Homo sapiens

ENCSR129ROE ENCSR · ENCODE

RNA-seq on K562 cells treated with an shRNA knockdown against SMN1. (SMN1_BGKLV24_B)

Homo sapiens

Analyses 0

No analyses match this query.