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2 results for “Schwann cells”
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Motoneuron expression profiling identifies an association between an axonal splice variant of HDGF-related protein 3 and peripheral myelination.
The Journal of biological chemistry · 2020 · 295(34): 12233-12246
Disorders that disrupt myelin formation during development or in adulthood, such as multiple sclerosis and peripheral neuropathies, lead to severe pathologies, illustrating myelin's crucial role in normal neural functioning. However, although our understanding of glial biology is increasing, the signals …
PMID 32647008 DOI ↗
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Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal.
PLoS genetics · 2019 · 15(3): e1007948
Glial cells regulate multiple aspects of synaptogenesis. In the absence of Schwann cells, a peripheral glial cell, motor neurons initially innervate muscle but then degenerate. Here, using a genetic approach, we show that neural activity-regulated negative factors produced by muscle …
PMID 30870413 DOI ↗
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Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal
Mus musculus · GPL13112
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