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2 results for “YBX1”
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Integrated multi-omic characterizations of the synapse reveal RNA processing factors and ubiquitin ligases associated with neurodevelopmental disorders.
Cell systems · 2025 · 16(4): 101204
The molecular composition of the excitatory synapse is incompletely defined due to its dynamic nature across developmental stages and neuronal populations. To address this gap, we apply proteomic mass spectrometry to characterize the synapse in multiple biological models, including the …
PMID 40054464 DOI ↗
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Global analysis of RNA-binding proteins identifies a positive feedback loop between LARP1 and MYC that promotes tumorigenesis.
Cellular and molecular life sciences : CMLS · 2022 · 79(3): 147
In addition to genomic alterations, aberrant changes in post-transcriptional regulation can modify gene function and drive cancer development. RNA-binding proteins (RBPs) are a large class of post-transcriptional regulators that have been increasingly implicated in carcinogenesis. By integrating multi-omics data, we …
PMID 35195778 DOI ↗
Datasets 3
RNA-seq on K562 cells treated with a CRISPR gRNA against YBX1. (YBX1-BGKcLV15)
Homo sapiens
RNA-seq on HepG2 cells treated with a CRISPR gRNA against YBX1. (YBX1-BGHcLV16)
Homo sapiens
Integrated proteomic and multi-mic characterizations of the synapse reveal RNA processing factor and ubiquitin ligases associated with neurodevelopment disorders
Homo sapiens · GPL24676
Analyses 0
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