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  1. Pairing beyond the Seed Supports MicroRNA Targeting Specificity.

    Molecular cell · 2016 · 64(2): 320-333

    To identify endogenous miRNA-target sites, we isolated AGO-bound RNAs from Caenorhabditis elegans by individual-nucleotide resolution crosslinking immunoprecipitation (iCLIP), which fortuitously also produced miRNA-target chimeric reads. Through the analysis of thousands of reproducible chimeras, pairing to the miRNA seed emerged as …

    PMID 27720646 DOI ↗

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