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2 results for “chromatin remodeling”

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  1. Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes.

    Cell reports · 2024 · 43(8): 114637

    Reactive changes of glial cells during neuroinflammation impact brain disorders and disease progression. Elucidating the mechanisms that control reactive gliosis may help us to understand brain pathophysiology and improve outcomes. Here, we report that adult ablation of autism spectrum disorder …

    PMID 39154337 DOI ↗

  2. Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment.

    Genes & development · 2013 · 27(21): 2332-44

    A critical but molecularly uncharacterized step in heart formation and regeneration is the process that commits progenitor cells to differentiate into cardiomyocytes. Here, we show that the endoderm-derived dual Nodal/bone morphogenetic protein (BMP) antagonist Cerberus-1 (Cer1) in embryonic stem cell …

    PMID 24186978 DOI ↗

Datasets 2

GSE135300 GSE · GEO

Next Generation Sequencing: in vivo genome-wide CRISPR sgRNA screen in primary cancer-initiating and propagating bcCML stem cells

Mus musculus · GPL21103

GSE21037 GSE · GEO

L1 retrotransposition in neurons is mediated by MeCP2

Homo sapiens · GPL6244

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