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1 result for “rational design”
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Rational design yields RNA-binding zinc finger domains with altered sequence specificity.
RNA (New York, N.Y.) · 2025 · 31(2): 150-163
Targeting and manipulating endogenous RNAs in a sequence-specific manner is essential for both understanding RNA biology and developing RNA-targeting therapeutics. RNA-binding zinc fingers (ZnFs) are excellent candidates as designer proteins to expand the RNA-targeting toolbox, due to their compact size …
PMID 39658359 DOI ↗
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