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GSE202051

GSE GEO
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Refined molecular taxonomy and treatment remodeling of pancreatic cancer using single-cell resolution

Organism: Homo sapiens
Platform: GPL20301
Samples: 74
Experiment Types:
Expression profiling by high throughput sequencing
Submitted: May 02 2022
Last Updated: Dec 13 2024
Status: Public on May 18 2022
Contact: Karthik,,Jagadeesh (Broad Institute)

Relations

BioProject: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA834096

Summary

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal and treatment-refractory cancer. Molecular stratification in pancreatic cancer remains rudimentary and does not yet inform clinical management or therapeutic development. Here we construct a high-resolution molecular landscape of the multicellular subtypes and spatial communities that compose PAC using single-nucleus RNA-seq and whole-transcriptome digital spatial profiling (SP) of 43 primary PDAC tumor specimens that either received neoadjuvant therapy or were treatment-naïve. We uncovered expression programs across malignant cells and fibroblasts, including a newly-identified neural-like progenitor malignant cell program that was enriched after chemotherapy and radiotherapy and associated with poor prognosis in independent cohorts. Integrating spatial and cellular profiles revealed three multicellular communities: classical, squamoid-basaloid, and treatment-enriched. Our refined molecular and cellular taxonomy can advance precision oncology in PAC through stratification in clinical trials and as roadmap for therapeutic targeting of specific cellular phenotypes and multicellular interactions.

Overall Design

18 specimens received no treatment prior to resection; 25 specimens received neoadjuvant chemoradiation therapy (e.g. CRT = FOLFIRINOX), losartan (L), and/or nivolumab (N) prior to resection; 2 specimens were non-malignant

Analysis (5 steps)

View Data Processing
Processing steps for GSE202051
  1. BCL files were converted to FASTQ using bcl2fastq2-v2.20.
  2. CellRanger v3.0.2 was used to demultiplex the FASTQ reads, align them to the hg38 human transcriptome (pre-mRNA) reference and extract the UMI and nuclei barcodes.
  3. We used CellBender remove-background to remove ambient RNA and other technical artifacts from the count matrices.
  4. Nuclei with over 10,000 UMI counts were filtered.
  5. UMI counts were normalized by the total number of UMIs per nucleus and converted to transcripts-per-10,000 (TP10K) as the final expression unit.

Supplementary Files (3)

GSE202051_adata_010nuc_10x.h5ad.gz Download
GSE202051_adata_010orgCRT_10x.h5ad.gz Download
GSE202051_totaldata-final-toshare.h5ad.gz Download
GEO Samples (74)
GSM6090425 GSM6090426 GSM6090427 GSM6090428 GSM6090429 GSM6090430 GSM6090431 GSM6090432 GSM6090433 GSM6090434 GSM6090435 GSM6090436 GSM6090437 GSM6090438 GSM6090439 GSM6090440 GSM6090441 GSM6090442 GSM6090443 GSM6090444 GSM6090445 GSM6090446 GSM6090447 GSM6090448 GSM6090449 GSM6090450 GSM6090451 GSM6090452 GSM6090453 GSM6090454 GSM6090455 GSM6090456 GSM6090457 GSM6090458 GSM6090459 GSM6090460 GSM6090461 GSM6090462 GSM6090463 GSM6090464 GSM6090465 GSM6090466 GSM6090467 GSM6090468 GSM6090469 GSM6090470 GSM6090471 GSM6090472 GSM6090473 GSM6090474 GSM6090475 GSM6090476 GSM6090477 GSM6090478 GSM6090479 GSM6090480 GSM6090481 GSM6090482 GSM6090483 GSM6090484 GSM6090485 GSM6090486 GSM6090487 GSM6090488 GSM6090489 GSM6090490 GSM6090491 GSM6090492 GSM6090493 GSM6090494 GSM6090495 GSM6090496 GSM6090497 GSM6090498

Dataset Citations (3)

PubMed citation (PMID 36185212)
PubMed citation (PMID 35902743)
PubMed citation (PMID 38975886)

SRA Experiments (74) and Runs (74)

Total: 533546 MB
SRX15110756 SRP373187 RNA-Seq PAIRED
GSM6090427: PDAC_U_3, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855851
BioProject: PRJNA834096
BioSample: SAMN28041185
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039376 161643725 21336971700 9483.39 PDAC_U_3_untreated-NSTnPo-PDAC_channel1_S7_L003_I1_001.fastq.gz, PDAC… SRA
SRX15110757 SRP373187 RNA-Seq PAIRED
GSM6090428: PDAC_U_4, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855852
BioProject: PRJNA834096
BioSample: SAMN28041184
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039375 22847175 3015827100 1507.45 SRR19039375.lite, SRR19039375, PDAC_U_4_untreated-NSTnPo-PDAC_channel… SRA
SRX15110758 SRP373187 RNA-Seq PAIRED
GSM6090429: PDAC_U_5, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855853
BioProject: PRJNA834096
BioSample: SAMN28041183
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039377 105032843 13864335276 5803.98 PDAC_U_5_untreated-NSTnPo-PDAC_channel1_S4_L001_I1_001.fastq.gz, PDAC… SRA
SRX15110759 SRP373187 RNA-Seq PAIRED
GSM6090430: PDAC_U_6, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855854
BioProject: PRJNA834096
BioSample: SAMN28041182
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039374 131817957 17399970324 8012.96 PDAC_U_6_untreated-NSTnPo-PDAC_channel1_S5_L002_I1_001.fastq.gz, PDAC… SRA
SRX15110760 SRP373187 RNA-Seq PAIRED
GSM6090431: PDAC_U_7, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855855
BioProject: PRJNA834096
BioSample: SAMN28041181
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039373 146149197 19291694004 8739.07 PDAC_U_7_untreated-NSTnPo-PDAC_channel1_S12_L004_I1_001.fastq.gz, PDA… SRA
SRX15110761 SRP373187 RNA-Seq PAIRED
GSM6090432: PDAC_U_8, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855856
BioProject: PRJNA834096
BioSample: SAMN28041180
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039372 85953595 11345874540 5426.05 PDAC_U_8_MGHR17_channel1_S9_L003_I1_001.fastq.gz, PDAC_U_8_MGHR17_cha… SRA
SRX15110762 SRP373187 RNA-Seq PAIRED
GSM6090433: PDAC_U_8, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855857
BioProject: PRJNA834096
BioSample: SAMN28041179
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039371 119919518 15829376376 6993.11 PDAC_U_8v2_MGHR17v2_channel1_S16_L007_I1_001.fastq.gz, PDAC_U_8v2_MGH… SRA
SRX15110763 SRP373187 RNA-Seq PAIRED
GSM6090434: PDAC_U_9, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855858
BioProject: PRJNA834096
BioSample: SAMN28041178
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039370 166730400 22008412800 8497.19 PDAC_U_9_treated-NSTnPo-PDAC_channel1_S2_L006_I1_001.fastq.gz, PDAC_U… SRA
SRX15110764 SRP373187 RNA-Seq PAIRED
GSM6090435: PDAC_U_10, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855859
BioProject: PRJNA834096
BioSample: SAMN28041177
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039369 149766307 19769152524 9277.39 PDAC_U_10_untreated-NSTnPo-PDAC_channel1_S2_L001_I1_001.fastq.gz, PDA… SRA
SRX15110765 SRP373187 RNA-Seq PAIRED
GSM6090436: PDAC_U_10, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855860
BioProject: PRJNA834096
BioSample: SAMN28041176
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039367 454334924 59972209968 24302.55 PDAC_U_10redo_untreated-NSTnPo-PDAC_channel1_S1_L003_I1_001.fastq.gz,… SRA
SRX15110766 SRP373187 RNA-Seq PAIRED
GSM6090437: PDAC_U_11, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855861
BioProject: PRJNA834096
BioSample: SAMN28041175
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039366 136428191 18008521212 8113.21 PDAC_U_11_untreated-NSTnPo-PDAC_channel1_S4_L002_I1_001.fastq.gz, PDA… SRA
SRX15110767 SRP373187 RNA-Seq PAIRED
GSM6090438: PDAC_U_12, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855862
BioProject: PRJNA834096
BioSample: SAMN28041174
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039368 123892408 16353797856 6929.37 PDAC_U_12_untreated-NSTnPo-PDAC_channel1_S9_L004_I1_001.fastq.gz, PDA… SRA
SRX15110768 SRP373187 RNA-Seq PAIRED
GSM6090439: PDAC_U_13, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855863
BioProject: PRJNA834096
BioSample: SAMN28041173
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039365 81857576 10805200032 5502.81 PDAC_U_13_untreated-NSTnPo-PDAC_channel1_S1_L005_I1_001.fastq.gz, PDA… SRA
SRX15110769 SRP373187 RNA-Seq PAIRED
GSM6090440: PDAC_U_14, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855864
BioProject: PRJNA834096
BioSample: SAMN28041172
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039352 134776986 17790562152 8235.73 PDAC_U_14_untreated-NSTnPo-PDAC_channel1_S9_L003_I1_001.fastq.gz, PDA… SRA
SRX15110770 SRP373187 RNA-Seq PAIRED
GSM6090488: Normal_MGHR13, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855865
BioProject: PRJNA834096
BioSample: SAMN28041124
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Normal
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039364 123756615 16335873180 7638.63 Normal_MGHR13_MGHR13_channel1_S14_L004_I1_001.fastq.gz, Normal_MGHR13… SRA
SRX15110771 SRP373187 RNA-Seq PAIRED
GSM6090489: Normal_MGHR13, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855866
BioProject: PRJNA834096
BioSample: SAMN28041123
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Normal
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039363 109879587 14504105484 6036.41 Normal_MGHR13v2_MGHR13v2_channel1_S13_L006_I1_001.fastq.gz, Normal_MG… SRA
SRX15110772 SRP373187 RNA-Seq PAIRED
GSM6090490: Normal_2675N replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855867
BioProject: PRJNA834096
BioSample: SAMN28041122
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Normal
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039362 24093033 3180280356 1282.65 Normal_2675N_untreated-NSTnPo-PDAC_channel1_S4_L007_I1_001.fastq.gz, … SRA
SRX15110773 SRP373187 RNA-Seq PAIRED
GSM6090491: Normal_2548, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855868
BioProject: PRJNA834096
BioSample: SAMN28041121
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Normal
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039361 83394920 11008129440 4782.76 Normal_2548_untreated-NSTnPo-PDAC_channel1_S1_L007_I1_001.fastq.gz, N… SRA
SRX15110774 SRP373187 RNA-Seq PAIRED
GSM6090492: Normal_2540N, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855869
BioProject: PRJNA834096
BioSample: SAMN28041120
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Normal
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039360 117156986 15464722152 6219.81 Normal_2540N_untreated-NSTnPo-PDAC_channel1_S3_L007_I1_001.fastq.gz, … SRA
SRX15110775 SRP373187 RNA-Seq PAIRED
GSM6090493: Normal_2517, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855870
BioProject: PRJNA834096
BioSample: SAMN28041119
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Normal
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039359 187790302 24788319864 10321.51 Normal_2517_untreated-TST-pancreas_channel1_S2_L008_I1_001.fastq.gz, … SRA
SRX15110776 SRP373187 RNA-Seq PAIRED
GSM6090494: Normal_2517, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855871
BioProject: PRJNA834096
BioSample: SAMN28041118
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Normal
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039358 196786053 25975758996 10890.13 Normal_2517_untreated-NSTnPo-pancreas_channel1_S3_L008_I1_001.fastq.g… SRA
SRX15110777 SRP373187 RNA-Seq PAIRED
GSM6090495: Normal_2517, replicate 3, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855872
BioProject: PRJNA834096
BioSample: SAMN28041117
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Normal
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039357 90203530 11906865960 4854.13 Normal_2517_untreated-CST-pancreas_channel1_S1_L008_I1_001.fastq.gz, … SRA
SRX15110778 SRP373187 RNA-Seq PAIRED
GSM6090496: Normal_010N, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855873
BioProject: PRJNA834096
BioSample: SAMN28041116
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Normal
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039356 44360582 5855596824 2392.67 Normal_010N_untreated-NSTnPo-PDAC_channel1_S10_L004_I1_001.fastq.gz, … SRA
SRX15110779 SRP373187 RNA-Seq PAIRED
GSM6090497: 010orgCRT, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855874
BioProject: PRJNA834096
BioSample: SAMN28041115
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: Patient-derived organoid
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039355 87852612 11596544784 4820.62 010orgCRT_treated-NSTnPo-PDAC_channel1_S5_L007_I1_001.fastq.gz, 010or… SRA
SRX15110780 SRP373187 RNA-Seq PAIRED
GSM6090498: 010nuc, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855875
BioProject: PRJNA834096
BioSample: SAMN28041114
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: Patient-derived organoid
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039354 126669057 16720315524 7131.46 010nuc_untreated-NSTnPo-PDAC_channel1_S8_L004_I1_001.fastq.gz, 010nuc… SRA
SRX15110781 SRP373187 RNA-Seq PAIRED
GSM6090425: PDAC_U_1, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855876
BioProject: PRJNA834096
BioSample: SAMN28041187
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039353 160680093 21209772276 8676.01 PDAC_U_1_untreated-NSTnPo-PDAC_channel1_S1_L001_I1_001.fastq.gz, PDAC… SRA
SRX15110782 SRP373187 RNA-Seq PAIRED
GSM6090426: PDAC_U_2, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855877
BioProject: PRJNA834096
BioSample: SAMN28041186
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039306 137205493 18111125076 8242.15 PDAC_U_2_untreated-NSTnPo-PDAC_channel1_S6_L002_I1_001.fastq.gz, PDAC… SRA
SRX15110783 SRP373187 RNA-Seq PAIRED
GSM6090441: PDAC_U_15, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855878
BioProject: PRJNA834096
BioSample: SAMN28041171
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039350 108431105 14312905860 7208.96 PDAC_U_15_untreated-NSTnPo-PDAC_channel1_S3_L005_I1_001.fastq.gz, PDA… SRA
SRX15110784 SRP373187 RNA-Seq PAIRED
GSM6090442: PDAC_U_16, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855879
BioProject: PRJNA834096
BioSample: SAMN28041170
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039349 171621681 22654061892 10057.09 PDAC_U_16_untreated-NSTnPo-PDAC_channel1_S1_L001_I1_001.fastq.gz, PDA… SRA
SRX15110785 SRP373187 RNA-Seq PAIRED
GSM6090443: PDAC_U_17, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855880
BioProject: PRJNA834096
BioSample: SAMN28041169
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039348 68448660 9035223120 4337.55 PDAC_U_17_MGHR16_channel1_S8_L002_I1_001.fastq.gz, PDAC_U_17_MGHR16_c… SRA
SRX15110786 SRP373187 RNA-Seq PAIRED
GSM6090444: PDAC_U_17, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855881
BioProject: PRJNA834096
BioSample: SAMN28041168
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039347 256945963 33916867116 14048.56 PDAC_U_17v2_MGHR16v2_channel1_S4_L003_I1_001.fastq.gz, PDAC_U_17v2_MG… SRA
SRX15110787 SRP373187 RNA-Seq PAIRED
GSM6090445: PDAC_U_18, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855882
BioProject: PRJNA834096
BioSample: SAMN28041167
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039346 36831982 4861821624 2338.02 PDAC_U_18_untreated-NSTnPo-PDAC_channel1_S4_L005_I1_001.fastq.gz, PDA… SRA
SRX15110788 SRP373187 RNA-Seq PAIRED
GSM6090446: PDAC_U_18, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855883
BioProject: PRJNA834096
BioSample: SAMN28041166
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Untreated
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039345 128205263 16923094716 7781.92 PDAC_U_18_untreated-NSTnPo-PDAC_channel1_S11_L004_I1_001.fastq.gz, PD… SRA
SRX15110789 SRP373187 RNA-Seq PAIRED
GSM6090447: PDAC_T_1, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855884
BioProject: PRJNA834096
BioSample: SAMN28041165
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039344 77268489 10199440548 4902.56 PDAC_T_1_MGHR5_channel1_S3_L001_I1_001.fastq.gz, PDAC_T_1_MGHR5_chann… SRA
SRX15110790 SRP373187 RNA-Seq PAIRED
GSM6090448: PDAC_T_1, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855885
BioProject: PRJNA834096
BioSample: SAMN28041164
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039343 318117985 41991574020 17747.99 PDAC_T_1v2_MGHR5v2_channel1_S8_L005_I1_001.fastq.gz, PDAC_T_1v2_MGHR5… SRA
SRX15110791 SRP373187 RNA-Seq PAIRED
GSM6090449: PDAC_T_2, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855886
BioProject: PRJNA834096
BioSample: SAMN28041163
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039342 131744535 17390278620 7416.39 PDAC_T_2_treated-NSTnPo-PDAC_channel1_S1_L006_I1_001.fastq.gz, PDAC_T… SRA
SRX15110792 SRP373187 RNA-Seq PAIRED
GSM6090450: PDAC_T_3, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855887
BioProject: PRJNA834096
BioSample: SAMN28041162
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039341 103464816 13657355712 6337.52 PDAC_T_3_MGHR4_channel1_S2_L001_I1_001.fastq.gz, PDAC_T_3_MGHR4_chann… SRA
SRX15110793 SRP373187 RNA-Seq PAIRED
GSM6090451: PDAC_T_3, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855888
BioProject: PRJNA834096
BioSample: SAMN28041161
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039340 115000686 15180090552 6307.47 PDAC_T_3v2_MGHR4v2_channel1_S19_L008_I1_001.fastq.gz, PDAC_T_3v2_MGHR… SRA
SRX15110794 SRP373187 RNA-Seq PAIRED
GSM6090452: PDAC_T_4, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855889
BioProject: PRJNA834096
BioSample: SAMN28041160
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039339 54011755 7129551660 2976.97 PDAC_T_4_treated-NSTnPo-PDAC_channel1_S2_L001_I1_001.fastq.gz, PDAC_T… SRA
SRX15110795 SRP373187 RNA-Seq PAIRED
GSM6090453: PDAC_T_5, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855890
BioProject: PRJNA834096
BioSample: SAMN28041159
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039338 160004219 21120556908 9477.94 PDAC_T_5_treated-NSTnPo-PDAC_channel1_S3_L007_I1_001.fastq.gz, PDAC_T… SRA
SRX15110796 SRP373187 RNA-Seq PAIRED
GSM6090454: PDAC_T_6, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855891
BioProject: PRJNA834096
BioSample: SAMN28041158
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039337 130726778 17255934696 7627.25 PDAC_T_6_treated-NSTnPo-PDAC_channel1_S1_L001_I1_001.fastq.gz, PDAC_T… SRA
SRX15110797 SRP373187 RNA-Seq PAIRED
GSM6090455: PDAC_T_6, replicate 2, snRNA-seq; Homo sapiens; RNA-Seq
Sample: SRS12855892
BioProject: PRJNA834096
BioSample: SAMN28041157
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039336 118380528 15626229696 6848.75 PDAC_T_6_treated-CST-PDAC_channel1_S2_L001_I1_001.fastq.gz, PDAC_T_6_… SRA
SRX15110798 SRP373187 RNA-Seq PAIRED
GSM6090456: PDAC_T_7, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855893
BioProject: PRJNA834096
BioSample: SAMN28041156
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039335 161978054 21381103128 9685.33 PDAC_T_7_treated-NSTnPo-PDAC_channel1_S2_L007_I1_001.fastq.gz, PDAC_T… SRA
SRX15110799 SRP373187 RNA-Seq PAIRED
GSM6090457: PDAC_T_8, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855894
BioProject: PRJNA834096
BioSample: SAMN28041155
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039334 31049483 4098531756 1763.0 PDAC_T_8_treated-NSTnPo-PDAC_channel1_S2_L006_I1_001.fastq.gz, PDAC_T… SRA
SRX15110800 SRP373187 RNA-Seq PAIRED
GSM6090458: PDAC_T_8, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855895
BioProject: PRJNA834096
BioSample: SAMN28041154
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039333 106917001 13578459127 6037.34 PDAC_T_8redo_MGH2101redo_channel1_S4_L001_I1_001.fastq.gz, PDAC_T_8re… SRA
SRX15110801 SRP373187 RNA-Seq PAIRED
GSM6090459: PDAC_T_8, replicate 3, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855896
BioProject: PRJNA834096
BioSample: SAMN28041153
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039332 129438394 17085868008 7335.41 PDAC_T_8v2_MGH2101v2_channel1_S6_L004_I1_001.fastq.gz, PDAC_T_8v2_MGH… SRA
SRX15110802 SRP373187 RNA-Seq PAIRED
GSM6090460: PDAC_T_9, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855897
BioProject: PRJNA834096
BioSample: SAMN28041152
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039331 72561176 9215269352 3987.69 PDAC_T_9_MGH2076_channel1_S1_L001_I1_001.fastq.gz, PDAC_T_9_MGH2076_c… SRA
SRX15110803 SRP373187 RNA-Seq PAIRED
GSM6090461: PDAC_T_9, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855898
BioProject: PRJNA834096
BioSample: SAMN28041151
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039330 21554961 2845254852 1209.88 PDAC_T_9v2_MGH2076v2_channel1_S9_L005_I1_001.fastq.gz, PDAC_T_9v2_MGH… SRA
SRX15110804 SRP373187 RNA-Seq PAIRED
GSM6090462: PDAC_T_10, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855899
BioProject: PRJNA834096
BioSample: SAMN28041150
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039329 87257530 11517993960 5552.68 PDAC_T_10_MGHR6_channel1_S4_L001_I1_001.fastq.gz, PDAC_T_10_MGHR6_cha… SRA
SRX15110805 SRP373187 RNA-Seq PAIRED
GSM6090463: PDAC_T_10, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855900
BioProject: PRJNA834096
BioSample: SAMN28041149
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039328 126609372 16712437104 6989.02 PDAC_T_10v2_MGHR6v2_channel1_S12_L006_I1_001.fastq.gz, PDAC_T_10v2_MG… SRA
SRX15110806 SRP373187 RNA-Seq PAIRED
GSM6090464: PDAC_T_11, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855901
BioProject: PRJNA834096
BioSample: SAMN28041148
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039327 93731696 12372583872 5823.36 PDAC_T_11_MGHR11_channel1_S12_L003_I1_001.fastq.gz, PDAC_T_11_MGHR11_… SRA
SRX15110807 SRP373187 RNA-Seq PAIRED
GSM6090465: PDAC_T_11, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855903
BioProject: PRJNA834096
BioSample: SAMN28041147
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039326 87538968 11555143776 5135.36 PDAC_T_11v2_MGHR11v2_channel1_S21_L008_I1_001.fastq.gz, PDAC_T_11v2_M… SRA
SRX15110808 SRP373187 RNA-Seq PAIRED
GSM6090466: PDAC_T_12, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855902
BioProject: PRJNA834096
BioSample: SAMN28041146
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039325 86081888 11362809216 5419.65 PDAC_T_12_MGHR7_channel1_S1_L001_I1_001.fastq.gz, PDAC_T_12_MGHR7_cha… SRA
SRX15110809 SRP373187 RNA-Seq PAIRED
GSM6090467: PDAC_T_12, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855904
BioProject: PRJNA834096
BioSample: SAMN28041145
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039324 128972242 17024335944 6989.08 PDAC_T_12v2_MGHR7v2_channel1_S11_L006_I1_001.fastq.gz, PDAC_T_12v2_MG… SRA
SRX15110810 SRP373187 RNA-Seq PAIRED
GSM6090468: PDAC_T_13, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855906
BioProject: PRJNA834096
BioSample: SAMN28041144
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039323 120734231 15936918492 7241.27 PDAC_T_13_treated-NSTnPo-PDAC_channel1_S10_L004_I1_001.fastq.gz, PDAC… SRA
SRX15110811 SRP373187 RNA-Seq PAIRED
GSM6090469: PDAC_T_13, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855905
BioProject: PRJNA834096
BioSample: SAMN28041143
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039322 97149640 12338004280 5460.31 PDAC_T_13redo_MGH2675redo_channel1_S3_L001_I1_001.fastq.gz, PDAC_T_13… SRA
SRX15110812 SRP373187 RNA-Seq PAIRED
GSM6090470: PDAC_T_13, replicate 3, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855907
BioProject: PRJNA834096
BioSample: SAMN28041142
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039321 102918199 13585202268 6093.42 PDAC_T_13v2_MGH2675v2_channel1_S10_L005_I1_001.fastq.gz, PDAC_T_13v2_… SRA
SRX15110813 SRP373187 RNA-Seq PAIRED
GSM6090471: PDAC_T_14, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855909
BioProject: PRJNA834096
BioSample: SAMN28041141
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039320 110300836 14559710352 6967.69 PDAC_T_14_MGHR1_channel1_S5_L002_I1_001.fastq.gz, PDAC_T_14_MGHR1_cha… SRA
SRX15110814 SRP373187 RNA-Seq PAIRED
GSM6090472: PDAC_T_14, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855908
BioProject: PRJNA834096
BioSample: SAMN28041140
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRT
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039319 186012569 24553659108 10351.28 PDAC_T_14v2_MGHR1v2_channel1_S15_L007_I1_001.fastq.gz, PDAC_T_14v2_MG… SRA
SRX15110815 SRP373187 RNA-Seq PAIRED
GSM6090473: PDAC_T_15, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855910
BioProject: PRJNA834096
BioSample: SAMN28041139
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRTL
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039318 65346980 8625801360 4195.28 PDAC_T_15_MGHR2_channel1_S6_L002_I1_001.fastq.gz, PDAC_T_15_MGHR2_cha… SRA
SRX15110816 SRP373187 RNA-Seq PAIRED
GSM6090474: PDAC_T_15, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855911
BioProject: PRJNA834096
BioSample: SAMN28041138
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRTL
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039317 186387830 24603193560 10330.26 PDAC_T_15v2_MGHR2v2_channel1_S3_L003_I1_001.fastq.gz, PDAC_T_15v2_MGH… SRA
SRX15110817 SRP373187 RNA-Seq PAIRED
GSM6090475: PDAC_T_16, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855912
BioProject: PRJNA834096
BioSample: SAMN28041137
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRTL
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039316 105164868 13881762576 5968.67 PDAC_T_16_treated-NSTnPo-PDAC_channel1_S4_L006_I1_001.fastq.gz, PDAC_… SRA
SRX15110818 SRP373187 RNA-Seq PAIRED
GSM6090476: PDAC_T_17, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855913
BioProject: PRJNA834096
BioSample: SAMN28041136
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRTL
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039315 32919709 4345401588 1686.21 PDAC_T_17_untreated-NSTnPo-PDAC_channel1_S1_L006_I1_001.fastq.gz, PDA… SRA
SRX15110819 SRP373187 RNA-Seq PAIRED
GSM6090477: PDAC_T_18, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855914
BioProject: PRJNA834096
BioSample: SAMN28041135
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRTL
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039351 141222311 18641345052 7696.7 PDAC_T_18_treated-NSTnPo-PDAC_channel1_S3_L001_I1_001.fastq.gz, PDAC_… SRA
SRX15110820 SRP373187 RNA-Seq PAIRED
GSM6090478: PDAC_T_19, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855915
BioProject: PRJNA834096
BioSample: SAMN28041134
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRTL
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039314 128495896 16318978792 7124.41 PDAC_T_19_MGH2381_channel1_S2_L001_I1_001.fastq.gz, PDAC_T_19_MGH2381… SRA
SRX15110821 SRP373187 RNA-Seq PAIRED
GSM6090479: PDAC_T_19, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855916
BioProject: PRJNA834096
BioSample: SAMN28041133
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRTL
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039313 28833076 3805966032 1659.2 PDAC_T_19v2_MGH2381v2_channel1_S18_L007_I1_001.fastq.gz, PDAC_T_19v2_… SRA
SRX15110822 SRP373187 RNA-Seq PAIRED
GSM6090480: PDAC_T_20, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855917
BioProject: PRJNA834096
BioSample: SAMN28041132
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRTN
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039312 136934532 18075358224 7130.35 PDAC_T_20_treated-NSTnPo-PDAC_channel1_S6_L005_I1_001.fastq.gz, PDAC_… SRA
SRX15110823 SRP373187 RNA-Seq PAIRED
GSM6090481: PDAC_T_21, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855918
BioProject: PRJNA834096
BioSample: SAMN28041131
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRTLN
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039311 76672347 10120749804 4841.04 PDAC_T_21_MGHR9_channel1_S10_L003_I1_001.fastq.gz, PDAC_T_21_MGHR9_ch… SRA
SRX15110824 SRP373187 RNA-Seq PAIRED
GSM6090482: PDAC_T_21, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855919
BioProject: PRJNA834096
BioSample: SAMN28041130
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: CRTLN
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039310 308644222 40741037304 16954.42 PDAC_T_21v2_MGHR9v2_channel1_S5_L004_I1_001.fastq.gz, PDAC_T_21v2_MGH… SRA
SRX15110825 SRP373187 RNA-Seq PAIRED
GSM6090483: PDAC_T_22, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855921
BioProject: PRJNA834096
BioSample: SAMN28041129
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: FOLFIRINOX, Gy/cisplatin
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039309 174846071 23079681372 9872.93 PDAC_T_22_treated-NSTnPo-PDAC_channel1_S3_L006_I1_001.fastq.gz, PDAC_… SRA
SRX15110826 SRP373187 RNA-Seq PAIRED
GSM6090484: PDAC_T_23, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855920
BioProject: PRJNA834096
BioSample: SAMN28041128
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: FOLFIRINOX, Gy/cisplatin
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039308 136619937 18033831684 7249.18 PDAC_T_23_treated-NSTnPo-PDAC_channel1_S5_L005_I1_001.fastq.gz, PDAC_… SRA
SRX15110827 SRP373187 RNA-Seq PAIRED
GSM6090485: PDAC_T_24, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855923
BioProject: PRJNA834096
BioSample: SAMN28041127
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Gem/abraxane, Gy/cape
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039307 3277 432564 0.31 PDAC_T_24_MGHR8_channel1_S17_L005_I1_001.fastq.gz, PDAC_T_24_MGHR8_ch… SRA
SRX15110828 SRP373187 RNA-Seq PAIRED
GSM6090486: PDAC_T_24, replicate 2, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855922
BioProject: PRJNA834096
BioSample: SAMN28041126
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Gem/abraxane, Gy/cape
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039305 445988754 58870515528 25408.83 PDAC_T_24v2_MGHR8v2_channel1_S1_L001_I1_001.fastq.gz, PDAC_T_24v2_MGH… SRA
SRX15110829 SRP373187 RNA-Seq PAIRED
GSM6090487: PDAC_T_25, replicate 1, snRNAseq; Homo sapiens; RNA-Seq
Sample: SRS12855924
BioProject: PRJNA834096
BioSample: SAMN28041125
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: Pancreas
tissue: Pancreas
cell line: NA
cell type: Tumor
treatment: Gy/cape
Original files (1)
Pancreas
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR19039304 97096272 12816707904 5858.41 PDAC_T_25_treated-NSTnPo-PDAC_channel1_S3_L001_I1_001.fastq.gz, PDAC_… SRA

Linked Publications (1)

A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer.
Nature communications · 2023

Data Files (74)

Accession File Name Stored Type Output Type Mapping Assembly Size Download
— 010nuc_untreated-NSTnPo-PDAC_channel1_S8_L004_I1_001.f… RNA-Seq 7.0 GB link
— 010orgCRT_treated-NSTnPo-PDAC_channel1_S5_L007_I1_001.… RNA-Seq 4.7 GB link
— Normal_010N_untreated-NSTnPo-PDAC_channel1_S10_L004_I1… RNA-Seq 2.3 GB link
— Normal_2517_untreated-CST-pancreas_channel1_S1_L008_I1… RNA-Seq 4.7 GB link
— Normal_2517_untreated-NSTnPo-pancreas_channel1_S3_L008… RNA-Seq 10.6 GB link
— Normal_2517_untreated-TST-pancreas_channel1_S2_L008_I1… RNA-Seq 10.1 GB link
— Normal_2540N_untreated-NSTnPo-PDAC_channel1_S3_L007_I1… RNA-Seq 6.1 GB link
— Normal_2548_untreated-NSTnPo-PDAC_channel1_S1_L007_I1_… RNA-Seq 4.7 GB link
— Normal_2675N_untreated-NSTnPo-PDAC_channel1_S4_L007_I1… RNA-Seq 1.3 GB link
— Normal_MGHR13_MGHR13_channel1_S14_L004_I1_001.fastq.gz RNA-Seq 7.5 GB link
— Normal_MGHR13v2_MGHR13v2_channel1_S13_L006_I1_001.fast… RNA-Seq 5.9 GB link
— PDAC_T_10_MGHR6_channel1_S4_L001_I1_001.fastq.gz RNA-Seq 5.4 GB link
— PDAC_T_10v2_MGHR6v2_channel1_S12_L006_I1_001.fastq.gz RNA-Seq 6.8 GB link
— PDAC_T_11_MGHR11_channel1_S12_L003_I1_001.fastq.gz RNA-Seq 5.7 GB link
— PDAC_T_11v2_MGHR11v2_channel1_S21_L008_I1_001.fastq.gz RNA-Seq 5.0 GB link
— PDAC_T_12_MGHR7_channel1_S1_L001_I1_001.fastq.gz RNA-Seq 5.3 GB link
— PDAC_T_12v2_MGHR7v2_channel1_S11_L006_I1_001.fastq.gz RNA-Seq 6.8 GB link
— PDAC_T_13redo_MGH2675redo_channel1_S3_L001_I1_001.fast… RNA-Seq 5.3 GB link
— PDAC_T_13_treated-NSTnPo-PDAC_channel1_S10_L004_I1_001… RNA-Seq 7.1 GB link
— PDAC_T_13v2_MGH2675v2_channel1_S10_L005_I1_001.fastq.gz RNA-Seq 6.0 GB link
— PDAC_T_14_MGHR1_channel1_S5_L002_I1_001.fastq.gz RNA-Seq 6.8 GB link
— PDAC_T_14v2_MGHR1v2_channel1_S15_L007_I1_001.fastq.gz RNA-Seq 10.1 GB link
— PDAC_T_15_MGHR2_channel1_S6_L002_I1_001.fastq.gz RNA-Seq 4.1 GB link
— PDAC_T_15v2_MGHR2v2_channel1_S3_L003_I1_001.fastq.gz RNA-Seq 10.1 GB link
— PDAC_T_16_treated-NSTnPo-PDAC_channel1_S4_L006_I1_001.… RNA-Seq 5.8 GB link
— PDAC_T_17_untreated-NSTnPo-PDAC_channel1_S1_L006_I1_00… RNA-Seq 1.6 GB link
— PDAC_T_18_treated-NSTnPo-PDAC_channel1_S3_L001_I1_001.… RNA-Seq 7.5 GB link
— PDAC_T_19_MGH2381_channel1_S2_L001_I1_001.fastq.gz RNA-Seq 7.0 GB link
— PDAC_T_19v2_MGH2381v2_channel1_S18_L007_I1_001.fastq.gz RNA-Seq 1.6 GB link
— PDAC_T_1_MGHR5_channel1_S3_L001_I1_001.fastq.gz RNA-Seq 4.8 GB link
— PDAC_T_1v2_MGHR5v2_channel1_S8_L005_I1_001.fastq.gz RNA-Seq 17.3 GB link
— PDAC_T_20_treated-NSTnPo-PDAC_channel1_S6_L005_I1_001.… RNA-Seq 7.0 GB link
— PDAC_T_21_MGHR9_channel1_S10_L003_I1_001.fastq.gz RNA-Seq 4.7 GB link
— PDAC_T_21v2_MGHR9v2_channel1_S5_L004_I1_001.fastq.gz RNA-Seq 16.6 GB link
— PDAC_T_22_treated-NSTnPo-PDAC_channel1_S3_L006_I1_001.… RNA-Seq 9.6 GB link
— PDAC_T_23_treated-NSTnPo-PDAC_channel1_S5_L005_I1_001.… RNA-Seq 7.1 GB link
— PDAC_T_24_MGHR8_channel1_S17_L005_I1_001.fastq.gz RNA-Seq 317.4 KB link
— PDAC_T_24v2_MGHR8v2_channel1_S1_L001_I1_001.fastq.gz RNA-Seq 24.8 GB link
— PDAC_T_25_treated-NSTnPo-PDAC_channel1_S3_L001_I1_001.… RNA-Seq 5.7 GB link
— PDAC_T_2_treated-NSTnPo-PDAC_channel1_S1_L006_I1_001.f… RNA-Seq 7.2 GB link
— PDAC_T_3_MGHR4_channel1_S2_L001_I1_001.fastq.gz RNA-Seq 6.2 GB link
— PDAC_T_3v2_MGHR4v2_channel1_S19_L008_I1_001.fastq.gz RNA-Seq 6.2 GB link
— PDAC_T_4_treated-NSTnPo-PDAC_channel1_S2_L001_I1_001.f… RNA-Seq 2.9 GB link
— PDAC_T_5_treated-NSTnPo-PDAC_channel1_S3_L007_I1_001.f… RNA-Seq 9.3 GB link
— PDAC_T_6_treated-CST-PDAC_channel1_S2_L001_I1_001.fast… RNA-Seq 6.7 GB link
— PDAC_T_6_treated-NSTnPo-PDAC_channel1_S1_L001_I1_001.f… RNA-Seq 7.4 GB link
— PDAC_T_7_treated-NSTnPo-PDAC_channel1_S2_L007_I1_001.f… RNA-Seq 9.5 GB link
— PDAC_T_8redo_MGH2101redo_channel1_S4_L001_I1_001.fastq… RNA-Seq 5.9 GB link
— PDAC_T_8_treated-NSTnPo-PDAC_channel1_S2_L006_I1_001.f… RNA-Seq 1.7 GB link
— PDAC_T_8v2_MGH2101v2_channel1_S6_L004_I1_001.fastq.gz RNA-Seq 7.2 GB link
— PDAC_T_9_MGH2076_channel1_S1_L001_I1_001.fastq.gz RNA-Seq 3.9 GB link
— PDAC_T_9v2_MGH2076v2_channel1_S9_L005_I1_001.fastq.gz RNA-Seq 1.2 GB link
— PDAC_U_10redo_untreated-NSTnPo-PDAC_channel1_S1_L003_I… RNA-Seq 23.7 GB link
— PDAC_U_10_untreated-NSTnPo-PDAC_channel1_S2_L001_I1_00… RNA-Seq 9.1 GB link
— PDAC_U_11_untreated-NSTnPo-PDAC_channel1_S4_L002_I1_00… RNA-Seq 7.9 GB link
— PDAC_U_12_untreated-NSTnPo-PDAC_channel1_S9_L004_I1_00… RNA-Seq 6.8 GB link
— PDAC_U_13_untreated-NSTnPo-PDAC_channel1_S1_L005_I1_00… RNA-Seq 5.4 GB link
— PDAC_U_14_untreated-NSTnPo-PDAC_channel1_S9_L003_I1_00… RNA-Seq 8.0 GB link
— PDAC_U_15_untreated-NSTnPo-PDAC_channel1_S3_L005_I1_00… RNA-Seq 7.0 GB link
— PDAC_U_16_untreated-NSTnPo-PDAC_channel1_S1_L001_I1_00… RNA-Seq 9.8 GB link
— PDAC_U_17_MGHR16_channel1_S8_L002_I1_001.fastq.gz RNA-Seq 4.2 GB link
— PDAC_U_17v2_MGHR16v2_channel1_S4_L003_I1_001.fastq.gz RNA-Seq 13.7 GB link
— PDAC_U_18_untreated-NSTnPo-PDAC_channel1_S11_L004_I1_0… RNA-Seq 7.6 GB link
— PDAC_U_18_untreated-NSTnPo-PDAC_channel1_S4_L005_I1_00… RNA-Seq 2.3 GB link
— PDAC_U_1_untreated-NSTnPo-PDAC_channel1_S1_L001_I1_001… RNA-Seq 8.5 GB link
— PDAC_U_2_untreated-NSTnPo-PDAC_channel1_S6_L002_I1_001… RNA-Seq 8.0 GB link
— PDAC_U_3_untreated-NSTnPo-PDAC_channel1_S7_L003_I1_001… RNA-Seq 9.3 GB link
— PDAC_U_5_untreated-NSTnPo-PDAC_channel1_S4_L001_I1_001… RNA-Seq 5.7 GB link
— PDAC_U_6_untreated-NSTnPo-PDAC_channel1_S5_L002_I1_001… RNA-Seq 7.8 GB link
— PDAC_U_7_untreated-NSTnPo-PDAC_channel1_S12_L004_I1_00… RNA-Seq 8.5 GB link
— PDAC_U_8_MGHR17_channel1_S9_L003_I1_001.fastq.gz RNA-Seq 5.3 GB link
— PDAC_U_8v2_MGHR17v2_channel1_S16_L007_I1_001.fastq.gz RNA-Seq 6.8 GB link
— PDAC_U_9_treated-NSTnPo-PDAC_channel1_S2_L006_I1_001.f… RNA-Seq 8.3 GB link
— SRR19039375.lite RNA-Seq 1.5 GB link