GSE5851
GSE GEOPhase II exploratory pharmacogenomics study of cetuximab monotherapy in patients with advanced metastatic CRC
Organism:
Homo sapiens
Platform:
GPL571
Samples:
80
Experiment Types:
Expression profiling by array
Submitted:
Sep 15 2006
Last Updated:
Dec 06 2018
Status:
Public on Jan 31 2008
Contact:
Shirin,Khambata,Ford (Bristol-Myers Squibb Pharmaceutical Research Institute)
Relations
BioProject: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA97257
Summary
Patients with metastatic colorectal cancer were enrolled for treatment with cetuximab monotherapy. Transcriptional profiling was conducted on RNA from pre-treatment metastatic site biopsies to identify genes whose expression correlates with best clinical responses. Keywords: comparison of disease control group versus non-responder group of patients
Overall Design
single pre-treatment metastatic biopsy from each patient analyzed
Analysis (1 step)
View Data Processing
Processing steps for GSE5851
- Data scaled to 1500 mean signal intensity value using GCOS 1.1.1.052
Supplementary Files (1)
GSE5851_RAW.tar
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GEO Samples (80)
GSM136578
GSM136579
GSM136580
GSM136581
GSM136582
GSM136583
GSM136584
GSM136585
GSM136586
GSM136587
GSM136588
GSM136589
GSM136590
GSM136591
GSM136592
GSM136593
GSM136594
GSM136595
GSM136596
GSM136597
GSM136598
GSM136599
GSM136600
GSM136601
GSM136602
GSM136603
GSM136604
GSM136605
GSM136606
GSM136607
GSM136608
GSM136609
GSM136610
GSM136611
GSM136612
GSM136613
GSM136614
GSM136615
GSM136616
GSM136617
GSM136618
GSM136619
GSM136620
GSM136621
GSM136622
GSM136623
GSM136624
GSM136625
GSM136626
GSM136627
GSM136628
GSM136629
GSM136630
GSM136631
GSM136632
GSM136633
GSM136634
GSM136635
GSM136636
GSM136637
GSM136638
GSM136639
GSM136640
GSM136641
GSM136642
GSM136643
GSM136644
GSM136645
GSM136646
GSM136647
GSM136648
GSM136649
GSM136650
GSM136651
GSM136652
GSM136653
GSM136654
GSM136655
GSM136656
GSM136657
Dataset Citations (1)
Linked Publications (1)
DDX5 promotes oncogene C3 and FABP1 expressions and drives intestinal inflammation and tumorigenesis.
Life science alliance · 2020