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ENCSR905NIK

ENCSR ENCODE
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RNA-seq on K562 cells treated with a CRISPR gRNA against SRSF4. (SRSF4-BGKcLV04-B)

Organism: Homo sapiens
Experiment Types:
CRISPR RNA-seq
Status: archived
Contact: Brenton Graveley, UConn

Summary

CRISPR RNA-seq of SRSF4 in Homo sapiens K562 genetically modified (deletion) using CRISPR targeting H. sapiens SRSF4

Overall Design

RNA-seq on K562 cells treated with a CRISPR gRNA against SRSF4. (SRSF4-BGKcLV04-B)

Analysis page is available for ENCSR905NIK.

Dataset Citations (1)

A large-scale binding and functional map of human RNA-binding proteins.
PMID 32728246 · 2020 · Nature
Eric L Van Nostrand, Peter Freese, Gabriel A Pratt, Xiaofeng Wang, Xintao Wei, Rui Xiao, Steven M Blue, Jia-Yu Chen, Neal A L Cody, Daniel Dominguez, Sara Olson, Balaji Sundararaman, Lijun Zhan, Cassandra Bazile, Louis Philip Benoit Bouvrette, Julie Bergalet, Michael O Duff, Keri E Garcia, Chelsea Gelboin-Burkhart, Myles Hochman, Nicole J Lambert, Hairi Li, Michael P McGurk, Thai B Nguyen, Tsultrim Palden, Ines Rabano, Shashank Sathe, Rebecca Stanton, Amanda Su, Ruth Wang, Brian A Yee, Bing Zhou, Ashley L Louie, Stefan Aigner, Xiang-Dong Fu, Eric Lécuyer, Christopher B Burge, Brenton R Graveley, Gene W Yeo

ENCODE Metadata

Total file size: 99.0 GB
Assay: CRISPR RNA-seq
Target: SRSF4
Biosample: Homo sapiens K562 genetically modified (deletion) using CRISPR targeting H. sapiens SRSF4
Files: 92
Unique ENC file IDs: 92
File Formats
bigWig (48) tsv (19) bam (18) fastq (4) tar (3)
Output types (11)
alignments (12) minus strand signal of all reads (12) minus strand signal of unique reads (12) plus strand signal of all reads (12) plus strand signal of unique reads (12) transcript quantifications (8) gene quantifications (6) transcriptome alignments (6) differential expression quantifications (5) reads (4) differential splicing quantifications (3)

Linked Publications (1)

Data Files (92)

Accession File Name Stored Type Output Type Mapping Assembly Size Download
ENCFF031QMZ ENCFF031QMZ.bam bam (alignments); assembly: GRCh38; genome annotation: V24 alignments GRCh38 3.6 GB link
ENCFF131QWX ENCFF131QWX.bam bam (alignments); assembly: GRCh38; genome annotation: V24 alignments GRCh38 3.7 GB link
ENCFF190CAM ENCFF190CAM.bam bam (alignments); assembly: GRCh38; genome annotation: V24 alignments GRCh38 4.7 GB link
ENCFF739RFY ENCFF739RFY.bam bam (alignments); assembly: GRCh38; genome annotation: V24 alignments GRCh38 4.5 GB link
ENCFF042IHR ENCFF042IHR.bam bam (alignments); assembly: GRCh38; genome annotation: V29 alignments GRCh38 4.5 GB link
ENCFF477FWA ENCFF477FWA.bam bam (alignments); assembly: GRCh38; genome annotation: V29 alignments GRCh38 4.7 GB link
ENCFF256VAD ENCFF256VAD.bam bam (alignments); assembly: hg19; genome annotation: V19 alignments hg19 3.6 GB link
ENCFF281TFT ENCFF281TFT.bam bam (alignments); assembly: hg19; genome annotation: V19 alignments hg19 4.4 GB link
ENCFF328QZE ENCFF328QZE.bam bam (alignments); assembly: hg19; genome annotation: V19 alignments hg19 4.5 GB link
ENCFF603EJP ENCFF603EJP.bam bam (alignments); assembly: hg19; genome annotation: V19 alignments hg19 3.7 GB link
ENCFF804MGA ENCFF804MGA.bam bam (alignments); assembly: hg19; genome annotation: V19 alignments hg19 3.6 GB link
ENCFF924ECF ENCFF924ECF.bam bam (alignments); assembly: hg19; genome annotation: V19 alignments hg19 3.7 GB link
ENCFF015VUX ENCFF015VUX.bam bam (transcriptome alignments); assembly: GRCh38; genome annotation: V24 transcriptome alignments GRCh38 5.7 GB link
ENCFF856HEC ENCFF856HEC.bam bam (transcriptome alignments); assembly: GRCh38; genome annotation: V24 transcriptome alignments GRCh38 5.4 GB link
ENCFF126OVL ENCFF126OVL.bam bam (transcriptome alignments); assembly: GRCh38; genome annotation: V29 transcriptome alignments GRCh38 6.5 GB link
ENCFF788BXM ENCFF788BXM.bam bam (transcriptome alignments); assembly: GRCh38; genome annotation: V29 transcriptome alignments GRCh38 6.2 GB link
ENCFF515FAH ENCFF515FAH.bam bam (transcriptome alignments); assembly: hg19; genome annotation: V19 transcriptome alignments hg19 5.3 GB link
ENCFF949VNU ENCFF949VNU.bam bam (transcriptome alignments); assembly: hg19; genome annotation: V19 transcriptome alignments hg19 5.6 GB link
ENCFF276OFA ENCFF276OFA.bigWig bigWig (minus strand signal of all reads); assembly: GRCh38; genome annotation: V24 minus strand signal of all reads GRCh38 93.2 MB link
ENCFF313ILN ENCFF313ILN.bigWig bigWig (minus strand signal of all reads); assembly: GRCh38; genome annotation: V24 minus strand signal of all reads GRCh38 104.3 MB link
ENCFF657UYP ENCFF657UYP.bigWig bigWig (minus strand signal of all reads); assembly: GRCh38; genome annotation: V24 minus strand signal of all reads GRCh38 94.3 MB link
ENCFF982DJA ENCFF982DJA.bigWig bigWig (minus strand signal of all reads); assembly: GRCh38; genome annotation: V24 minus strand signal of all reads GRCh38 107.8 MB link
ENCFF600GWQ ENCFF600GWQ.bigWig bigWig (minus strand signal of all reads); assembly: GRCh38; genome annotation: V29 minus strand signal of all reads GRCh38 107.8 MB link
ENCFF655PIF ENCFF655PIF.bigWig bigWig (minus strand signal of all reads); assembly: GRCh38; genome annotation: V29 minus strand signal of all reads GRCh38 104.3 MB link
ENCFF043OVT ENCFF043OVT.bigWig bigWig (minus strand signal of all reads); assembly: hg19; genome annotation: V19 minus strand signal of all reads hg19 91.9 MB link
ENCFF406QII ENCFF406QII.bigWig bigWig (minus strand signal of all reads); assembly: hg19; genome annotation: V19 minus strand signal of all reads hg19 89.9 MB link
ENCFF422RBD ENCFF422RBD.bigWig bigWig (minus strand signal of all reads); assembly: hg19; genome annotation: V19 minus strand signal of all reads hg19 95.6 MB link
ENCFF654GUG ENCFF654GUG.bigWig bigWig (minus strand signal of all reads); assembly: hg19; genome annotation: V19 minus strand signal of all reads hg19 105.8 MB link
ENCFF968NEU ENCFF968NEU.bigWig bigWig (minus strand signal of all reads); assembly: hg19; genome annotation: V19 minus strand signal of all reads hg19 96.9 MB link
ENCFF984WDA ENCFF984WDA.bigWig bigWig (minus strand signal of all reads); assembly: hg19; genome annotation: V19 minus strand signal of all reads hg19 102.5 MB link
ENCFF236FUD ENCFF236FUD.bigWig bigWig (minus strand signal of unique reads); assembly: GRCh38; genome annotation: V24 minus strand signal of unique reads GRCh38 92.4 MB link
ENCFF651HBD ENCFF651HBD.bigWig bigWig (minus strand signal of unique reads); assembly: GRCh38; genome annotation: V24 minus strand signal of unique reads GRCh38 94.8 MB link
ENCFF710HBC ENCFF710HBC.bigWig bigWig (minus strand signal of unique reads); assembly: GRCh38; genome annotation: V24 minus strand signal of unique reads GRCh38 88.5 MB link
ENCFF810YSJ ENCFF810YSJ.bigWig bigWig (minus strand signal of unique reads); assembly: GRCh38; genome annotation: V24 minus strand signal of unique reads GRCh38 85.9 MB link
ENCFF677OOV ENCFF677OOV.bigWig bigWig (minus strand signal of unique reads); assembly: GRCh38; genome annotation: V29 minus strand signal of unique reads GRCh38 94.8 MB link
ENCFF931QCH ENCFF931QCH.bigWig bigWig (minus strand signal of unique reads); assembly: GRCh38; genome annotation: V29 minus strand signal of unique reads GRCh38 92.6 MB link
ENCFF097BOP ENCFF097BOP.bigWig bigWig (minus strand signal of unique reads); assembly: hg19; genome annotation: V19 minus strand signal of unique reads hg19 88.1 MB link
ENCFF144SCX ENCFF144SCX.bigWig bigWig (minus strand signal of unique reads); assembly: hg19; genome annotation: V19 minus strand signal of unique reads hg19 91.3 MB link
ENCFF209FXB ENCFF209FXB.bigWig bigWig (minus strand signal of unique reads); assembly: hg19; genome annotation: V19 minus strand signal of unique reads hg19 81.8 MB link
ENCFF266OBD ENCFF266OBD.bigWig bigWig (minus strand signal of unique reads); assembly: hg19; genome annotation: V19 minus strand signal of unique reads hg19 86.7 MB link
ENCFF867POG ENCFF867POG.bigWig bigWig (minus strand signal of unique reads); assembly: hg19; genome annotation: V19 minus strand signal of unique reads hg19 93.8 MB link
ENCFF991ALR ENCFF991ALR.bigWig bigWig (minus strand signal of unique reads); assembly: hg19; genome annotation: V19 minus strand signal of unique reads hg19 83.1 MB link
ENCFF305PWR ENCFF305PWR.bigWig bigWig (plus strand signal of all reads); assembly: GRCh38; genome annotation: V24 plus strand signal of all reads GRCh38 94.5 MB link
ENCFF421KTQ ENCFF421KTQ.bigWig bigWig (plus strand signal of all reads); assembly: GRCh38; genome annotation: V24 plus strand signal of all reads GRCh38 109.6 MB link
ENCFF702LOG ENCFF702LOG.bigWig bigWig (plus strand signal of all reads); assembly: GRCh38; genome annotation: V24 plus strand signal of all reads GRCh38 105.6 MB link
ENCFF795SHZ ENCFF795SHZ.bigWig bigWig (plus strand signal of all reads); assembly: GRCh38; genome annotation: V24 plus strand signal of all reads GRCh38 95.8 MB link
ENCFF094WDO ENCFF094WDO.bigWig bigWig (plus strand signal of all reads); assembly: GRCh38; genome annotation: V29 plus strand signal of all reads GRCh38 109.6 MB link
ENCFF708PPM ENCFF708PPM.bigWig bigWig (plus strand signal of all reads); assembly: GRCh38; genome annotation: V29 plus strand signal of all reads GRCh38 105.7 MB link
ENCFF124AGE ENCFF124AGE.bigWig bigWig (plus strand signal of all reads); assembly: hg19; genome annotation: V19 plus strand signal of all reads hg19 97.5 MB link
ENCFF193YII ENCFF193YII.bigWig bigWig (plus strand signal of all reads); assembly: hg19; genome annotation: V19 plus strand signal of all reads hg19 93.8 MB link
ENCFF246QMI ENCFF246QMI.bigWig bigWig (plus strand signal of all reads); assembly: hg19; genome annotation: V19 plus strand signal of all reads hg19 91.6 MB link
ENCFF418ZFA ENCFF418ZFA.bigWig bigWig (plus strand signal of all reads); assembly: hg19; genome annotation: V19 plus strand signal of all reads hg19 104.0 MB link
ENCFF452FDF ENCFF452FDF.bigWig bigWig (plus strand signal of all reads); assembly: hg19; genome annotation: V19 plus strand signal of all reads hg19 98.9 MB link
ENCFF785BDC ENCFF785BDC.bigWig bigWig (plus strand signal of all reads); assembly: hg19; genome annotation: V19 plus strand signal of all reads hg19 107.7 MB link
ENCFF083WCS ENCFF083WCS.bigWig bigWig (plus strand signal of unique reads); assembly: GRCh38; genome annotation: V24 plus strand signal of unique reads GRCh38 87.6 MB link
ENCFF675VXO ENCFF675VXO.bigWig bigWig (plus strand signal of unique reads); assembly: GRCh38; genome annotation: V24 plus strand signal of unique reads GRCh38 90.7 MB link
ENCFF934HAZ ENCFF934HAZ.bigWig bigWig (plus strand signal of unique reads); assembly: GRCh38; genome annotation: V24 plus strand signal of unique reads GRCh38 94.5 MB link
ENCFF947EZP ENCFF947EZP.bigWig bigWig (plus strand signal of unique reads); assembly: GRCh38; genome annotation: V24 plus strand signal of unique reads GRCh38 97.2 MB link
ENCFF272LJR ENCFF272LJR.bigWig bigWig (plus strand signal of unique reads); assembly: GRCh38; genome annotation: V29 plus strand signal of unique reads GRCh38 94.6 MB link
ENCFF428CZR ENCFF428CZR.bigWig bigWig (plus strand signal of unique reads); assembly: GRCh38; genome annotation: V29 plus strand signal of unique reads GRCh38 97.3 MB link
ENCFF124YYU ENCFF124YYU.bigWig bigWig (plus strand signal of unique reads); assembly: hg19; genome annotation: V19 plus strand signal of unique reads hg19 84.0 MB link
ENCFF163AFJ ENCFF163AFJ.bigWig bigWig (plus strand signal of unique reads); assembly: hg19; genome annotation: V19 plus strand signal of unique reads hg19 93.6 MB link
ENCFF689QUJ ENCFF689QUJ.bigWig bigWig (plus strand signal of unique reads); assembly: hg19; genome annotation: V19 plus strand signal of unique reads hg19 90.7 MB link
ENCFF778NLK ENCFF778NLK.bigWig bigWig (plus strand signal of unique reads); assembly: hg19; genome annotation: V19 plus strand signal of unique reads hg19 85.6 MB link
ENCFF949RDR ENCFF949RDR.bigWig bigWig (plus strand signal of unique reads); assembly: hg19; genome annotation: V19 plus strand signal of unique reads hg19 96.5 MB link
ENCFF998HBM ENCFF998HBM.bigWig bigWig (plus strand signal of unique reads); assembly: hg19; genome annotation: V19 plus strand signal of unique reads hg19 89.0 MB link
ENCFF097YET ENCFF097YET.fastq fastq (reads) reads 2.6 GB link
ENCFF103ZTW ENCFF103ZTW.fastq fastq (reads) reads 2.7 GB link
ENCFF191FIB ENCFF191FIB.fastq fastq (reads) reads 2.7 GB link
ENCFF485AVX ENCFF485AVX.fastq fastq (reads) reads 2.6 GB link
ENCFF500DHJ ENCFF500DHJ.tar tar (differential splicing quantifications); assembly: hg19; genome annotation: V19 differential splicing quantifications hg19 12.3 MB link
ENCFF525IFF ENCFF525IFF.tar tar (differential splicing quantifications); assembly: hg19; genome annotation: V19 differential splicing quantifications hg19 3.6 MB link
ENCFF820OWS ENCFF820OWS.tar tar (differential splicing quantifications); assembly: hg19; genome annotation: V19 differential splicing quantifications hg19 4.1 MB link
ENCFF019IZV ENCFF019IZV.tsv tsv (differential expression quantifications); assembly: hg19; genome annotation: V19 differential expression quantifications hg19 5.6 MB link
ENCFF132NEZ ENCFF132NEZ.tsv tsv (differential expression quantifications); assembly: hg19; genome annotation: V19 differential expression quantifications hg19 1.8 MB link
ENCFF598JCC ENCFF598JCC.tsv tsv (differential expression quantifications); assembly: hg19; genome annotation: V19 differential expression quantifications hg19 2.9 MB link
ENCFF623BTU ENCFF623BTU.tsv tsv (differential expression quantifications); assembly: hg19; genome annotation: V19 differential expression quantifications hg19 1.9 MB link
ENCFF930NLB ENCFF930NLB.tsv tsv (differential expression quantifications); assembly: hg19; genome annotation: V19 differential expression quantifications hg19 4.3 MB link
ENCFF141OWV ENCFF141OWV.tsv tsv (gene quantifications); assembly: GRCh38; genome annotation: V24 gene quantifications GRCh38 9.5 MB link
ENCFF646IUC ENCFF646IUC.tsv tsv (gene quantifications); assembly: GRCh38; genome annotation: V24 gene quantifications GRCh38 9.5 MB link
ENCFF286DJP ENCFF286DJP.tsv tsv (gene quantifications); assembly: GRCh38; genome annotation: V29 gene quantifications GRCh38 10.4 MB link
ENCFF353JLM ENCFF353JLM.tsv tsv (gene quantifications); assembly: GRCh38; genome annotation: V29 gene quantifications GRCh38 10.4 MB link
ENCFF052ZHR ENCFF052ZHR.tsv tsv (gene quantifications); assembly: hg19; genome annotation: V19 gene quantifications hg19 9.1 MB link
ENCFF351WXH ENCFF351WXH.tsv tsv (gene quantifications); assembly: hg19; genome annotation: V19 gene quantifications hg19 9.1 MB link
ENCFF626QLO ENCFF626QLO.tsv tsv (transcript quantifications); assembly: GRCh38; genome annotation: V24 transcript quantifications GRCh38 25.3 MB link
ENCFF685YTN ENCFF685YTN.tsv tsv (transcript quantifications); assembly: GRCh38; genome annotation: V24 transcript quantifications GRCh38 25.3 MB link
ENCFF018BCZ ENCFF018BCZ.tsv tsv (transcript quantifications); assembly: GRCh38; genome annotation: V29 transcript quantifications GRCh38 29.8 MB link
ENCFF024HQA ENCFF024HQA.tsv tsv (transcript quantifications); assembly: GRCh38; genome annotation: V29 transcript quantifications GRCh38 27.4 MB link
ENCFF760IXJ ENCFF760IXJ.tsv tsv (transcript quantifications); assembly: GRCh38; genome annotation: V29 transcript quantifications GRCh38 27.4 MB link
ENCFF885EJU ENCFF885EJU.tsv tsv (transcript quantifications); assembly: GRCh38; genome annotation: V29 transcript quantifications GRCh38 29.8 MB link
ENCFF545HPZ ENCFF545HPZ.tsv tsv (transcript quantifications); assembly: hg19; genome annotation: V19 transcript quantifications hg19 24.9 MB link
ENCFF948XUH ENCFF948XUH.tsv tsv (transcript quantifications); assembly: hg19; genome annotation: V19 transcript quantifications hg19 24.9 MB link