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ENCSR992JGE

ENCSR ENCODE
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shRNA knockdown against METAP2 in HepG2 cells followed by RNA-seq. (METAP2_BGHLV16)

Organism: Homo sapiens
Experiment Types:
shRNA RNA-seq
Status: released
Contact: Brenton Graveley, UConn

Summary

shRNA RNA-seq of METAP2 in Homo sapiens HepG2 expressing RNAi targeting H. sapiens METAP2

Overall Design

shRNA knockdown against METAP2 in HepG2 cells followed by RNA-seq. (METAP2_BGHLV16)

Analysis page is available for ENCSR992JGE.

Dataset Citations (3)

A large-scale binding and functional map of human RNA-binding proteins.
PMID 32728246 · 2020 · Nature
Eric L Van Nostrand, Peter Freese, Gabriel A Pratt, Xiaofeng Wang, Xintao Wei, Rui Xiao, Steven M Blue, Jia-Yu Chen, Neal A L Cody, Daniel Dominguez, Sara Olson, Balaji Sundararaman, Lijun Zhan, Cassandra Bazile, Louis Philip Benoit Bouvrette, Julie Bergalet, Michael O Duff, Keri E Garcia, Chelsea Gelboin-Burkhart, Myles Hochman, Nicole J Lambert, Hairi Li, Michael P McGurk, Thai B Nguyen, Tsultrim Palden, Ines Rabano, Shashank Sathe, Rebecca Stanton, Amanda Su, Ruth Wang, Brian A Yee, Bing Zhou, Ashley L Louie, Stefan Aigner, Xiang-Dong Fu, Eric Lécuyer, Christopher B Burge, Brenton R Graveley, Gene W Yeo

ENCODE Metadata

Total file size: 158.7 GB
Assay: shRNA RNA-seq
Target: METAP2
Biosample: Homo sapiens HepG2 expressing RNAi targeting H. sapiens METAP2
Files: 120
Unique ENC file IDs: 120
File Formats
bigWig (64) bam (24) tsv (23) fastq (6) tar (3)
Output types (11)
alignments (16) minus strand signal of all reads (16) minus strand signal of unique reads (16) plus strand signal of all reads (16) plus strand signal of unique reads (16) transcript quantifications (10) gene quantifications (8) transcriptome alignments (8) reads (6) differential expression quantifications (5) differential splicing quantifications (3)

Linked Publications (1)

Data Files (120)

Accession File Name Stored Type Output Type Mapping Assembly Size Download
ENCFF027VYC ENCFF027VYC.bam bam (alignments) alignments 6.6 GB link
ENCFF095WYC ENCFF095WYC.bam bam (alignments) alignments 1.0 GB link
ENCFF099GRI ENCFF099GRI.bam bam (alignments) alignments 3.2 GB link
ENCFF210PZH ENCFF210PZH.bam bam (alignments) alignments 8.2 GB link
ENCFF249ZQO ENCFF249ZQO.bam bam (alignments) alignments 3.4 GB link
ENCFF261IUT ENCFF261IUT.bam bam (alignments) alignments 2.9 GB link
ENCFF276LQJ ENCFF276LQJ.bam bam (alignments) alignments 5.4 GB link
ENCFF350WJW ENCFF350WJW.bam bam (alignments) alignments 6.6 GB link
ENCFF411JUJ ENCFF411JUJ.bam bam (alignments) alignments 6.6 GB link
ENCFF576KFF ENCFF576KFF.bam bam (alignments) alignments 6.8 GB link
ENCFF619KWP ENCFF619KWP.bam bam (alignments) alignments 6.5 GB link
ENCFF672RCN ENCFF672RCN.bam bam (alignments) alignments 7.8 GB link
ENCFF682JKD ENCFF682JKD.bam bam (alignments) alignments 5.4 GB link
ENCFF685KDJ ENCFF685KDJ.bam bam (alignments) alignments 5.5 GB link
ENCFF902TQC ENCFF902TQC.bam bam (alignments) alignments 3.9 GB link
ENCFF984WOK ENCFF984WOK.bam bam (alignments) alignments 3.9 GB link
ENCFF138SMJ ENCFF138SMJ.bam bam (transcriptome alignments) transcriptome alignments 8.5 GB link
ENCFF233MAH ENCFF233MAH.bam bam (transcriptome alignments) transcriptome alignments 4.7 GB link
ENCFF379VZE ENCFF379VZE.bam bam (transcriptome alignments) transcriptome alignments 9.7 GB link
ENCFF466WMP ENCFF466WMP.bam bam (transcriptome alignments) transcriptome alignments 9.4 GB link
ENCFF590HQE ENCFF590HQE.bam bam (transcriptome alignments) transcriptome alignments 4.2 GB link
ENCFF698SVW ENCFF698SVW.bam bam (transcriptome alignments) transcriptome alignments 9.5 GB link
ENCFF855KOH ENCFF855KOH.bam bam (transcriptome alignments) transcriptome alignments 8.6 GB link
ENCFF990EBM ENCFF990EBM.bam bam (transcriptome alignments) transcriptome alignments 4.1 GB link
ENCFF009CAI ENCFF009CAI.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 44.5 MB link
ENCFF064AXI ENCFF064AXI.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 97.0 MB link
ENCFF103ZLT ENCFF103ZLT.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 107.4 MB link
ENCFF142QDM ENCFF142QDM.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 100.4 MB link
ENCFF313FAQ ENCFF313FAQ.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 100.5 MB link
ENCFF335MVU ENCFF335MVU.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 106.6 MB link
ENCFF382ZTY ENCFF382ZTY.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 44.8 MB link
ENCFF409OLU ENCFF409OLU.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 94.7 MB link
ENCFF446BYV ENCFF446BYV.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 19.8 MB link
ENCFF570ENS ENCFF570ENS.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 91.6 MB link
ENCFF783QRI ENCFF783QRI.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 44.8 MB link
ENCFF800PIL ENCFF800PIL.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 89.2 MB link
ENCFF857IYO ENCFF857IYO.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 100.7 MB link
ENCFF872FIO ENCFF872FIO.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 92.3 MB link
ENCFF896KBG ENCFF896KBG.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 39.6 MB link
ENCFF965HYP ENCFF965HYP.bigWig bigWig (minus strand signal of all reads) minus strand signal of all reads 38.7 MB link
ENCFF024GEM ENCFF024GEM.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 91.4 MB link
ENCFF064OKZ ENCFF064OKZ.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 88.6 MB link
ENCFF085TZL ENCFF085TZL.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 85.7 MB link
ENCFF090FZR ENCFF090FZR.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 40.4 MB link
ENCFF100LTU ENCFF100LTU.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 36.6 MB link
ENCFF180HPV ENCFF180HPV.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 94.9 MB link
ENCFF191YBX ENCFF191YBX.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 86.8 MB link
ENCFF218QBS ENCFF218QBS.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 95.6 MB link
ENCFF315MQJ ENCFF315MQJ.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 40.5 MB link
ENCFF404HVV ENCFF404HVV.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 18.5 MB link
ENCFF587SPQ ENCFF587SPQ.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 90.2 MB link
ENCFF725JND ENCFF725JND.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 36.9 MB link
ENCFF757FUS ENCFF757FUS.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 40.5 MB link
ENCFF760ULC ENCFF760ULC.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 91.3 MB link
ENCFF926NCM ENCFF926NCM.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 83.4 MB link
ENCFF948PWD ENCFF948PWD.bigWig bigWig (minus strand signal of unique reads) minus strand signal of unique reads 91.4 MB link
ENCFF019DII ENCFF019DII.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 91.3 MB link
ENCFF047GWP ENCFF047GWP.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 39.5 MB link
ENCFF057TVG ENCFF057TVG.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 108.3 MB link
ENCFF145NEH ENCFF145NEH.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 20.4 MB link
ENCFF172BYQ ENCFF172BYQ.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 109.3 MB link
ENCFF306GWQ ENCFF306GWQ.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 102.4 MB link
ENCFF313CRG ENCFF313CRG.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 96.6 MB link
ENCFF340EFN ENCFF340EFN.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 102.6 MB link
ENCFF356VAH ENCFF356VAH.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 45.9 MB link
ENCFF385SHU ENCFF385SHU.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 45.4 MB link
ENCFF434JBP ENCFF434JBP.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 45.9 MB link
ENCFF467HYU ENCFF467HYU.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 99.0 MB link
ENCFF500PKM ENCFF500PKM.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 102.5 MB link
ENCFF542RGK ENCFF542RGK.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 40.5 MB link
ENCFF655JHF ENCFF655JHF.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 94.4 MB link
ENCFF730JXL ENCFF730JXL.bigWig bigWig (plus strand signal of all reads) plus strand signal of all reads 93.4 MB link
ENCFF057REB ENCFF057REB.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 97.4 MB link
ENCFF079BRQ ENCFF079BRQ.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 94.0 MB link
ENCFF105SGU ENCFF105SGU.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 94.0 MB link
ENCFF132EJC ENCFF132EJC.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 98.2 MB link
ENCFF160EEX ENCFF160EEX.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 19.0 MB link
ENCFF199RTK ENCFF199RTK.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 86.1 MB link
ENCFF249SPU ENCFF249SPU.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 41.6 MB link
ENCFF308JQW ENCFF308JQW.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 90.9 MB link
ENCFF483PVZ ENCFF483PVZ.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 41.6 MB link
ENCFF521TMV ENCFF521TMV.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 89.3 MB link
ENCFF546CMU ENCFF546CMU.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 37.5 MB link
ENCFF615GWI ENCFF615GWI.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 88.0 MB link
ENCFF656YJQ ENCFF656YJQ.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 37.9 MB link
ENCFF702GPI ENCFF702GPI.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 94.0 MB link
ENCFF723VPR ENCFF723VPR.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 41.6 MB link
ENCFF919RTN ENCFF919RTN.bigWig bigWig (plus strand signal of unique reads) plus strand signal of unique reads 92.8 MB link
ENCFF383DSE ENCFF383DSE.fastq fastq (reads) reads 3.7 GB link
ENCFF485ZGX ENCFF485ZGX.fastq fastq (reads) reads 3.8 GB link
ENCFF499ITZ ENCFF499ITZ.fastq fastq (reads) reads 1.3 GB link
ENCFF553WDY ENCFF553WDY.fastq fastq (reads) reads 660.5 MB link
ENCFF721IPD ENCFF721IPD.fastq fastq (reads) reads 747.1 MB link
ENCFF876QNA ENCFF876QNA.fastq fastq (reads) reads 1.3 GB link
ENCFF086WEK ENCFF086WEK.tar tar (differential splicing quantifications) differential splicing quantifications 13.3 MB link
ENCFF525CDN ENCFF525CDN.tar tar (differential splicing quantifications) differential splicing quantifications 3.6 MB link
ENCFF819TDF ENCFF819TDF.tar tar (differential splicing quantifications) differential splicing quantifications 3.2 MB link
ENCFF005PYY ENCFF005PYY.tsv tsv (differential expression quantifications) differential expression quantifications 4.2 MB link
ENCFF317JZW ENCFF317JZW.tsv tsv (differential expression quantifications) differential expression quantifications 1.8 MB link
ENCFF528RSZ ENCFF528RSZ.tsv tsv (differential expression quantifications) differential expression quantifications 1.9 MB link
ENCFF669COR ENCFF669COR.tsv tsv (differential expression quantifications) differential expression quantifications 5.6 MB link
ENCFF965AWQ ENCFF965AWQ.tsv tsv (differential expression quantifications) differential expression quantifications 2.9 MB link
ENCFF003USJ ENCFF003USJ.tsv tsv (gene quantifications) gene quantifications 10.4 MB link
ENCFF307VUX ENCFF307VUX.tsv tsv (gene quantifications) gene quantifications 9.1 MB link
ENCFF338PPV ENCFF338PPV.tsv tsv (gene quantifications) gene quantifications 9.5 MB link
ENCFF341QIE ENCFF341QIE.tsv tsv (gene quantifications) gene quantifications 10.4 MB link
ENCFF352ZIK ENCFF352ZIK.tsv tsv (gene quantifications) gene quantifications 9.1 MB link
ENCFF448DNR ENCFF448DNR.tsv tsv (gene quantifications) gene quantifications 9.1 MB link
ENCFF700BBI ENCFF700BBI.tsv tsv (gene quantifications) gene quantifications 9.4 MB link
ENCFF764LGP ENCFF764LGP.tsv tsv (gene quantifications) gene quantifications 9.5 MB link
ENCFF017FWB ENCFF017FWB.tsv tsv (transcript quantifications) transcript quantifications 29.8 MB link
ENCFF136SCL ENCFF136SCL.tsv tsv (transcript quantifications) transcript quantifications 24.9 MB link
ENCFF174VBY ENCFF174VBY.tsv tsv (transcript quantifications) transcript quantifications 29.8 MB link
ENCFF423EUN ENCFF423EUN.tsv tsv (transcript quantifications) transcript quantifications 27.2 MB link
ENCFF430TDG ENCFF430TDG.tsv tsv (transcript quantifications) transcript quantifications 27.4 MB link
ENCFF550HER ENCFF550HER.tsv tsv (transcript quantifications) transcript quantifications 24.9 MB link
ENCFF655KPQ ENCFF655KPQ.tsv tsv (transcript quantifications) transcript quantifications 25.3 MB link
ENCFF695HEY ENCFF695HEY.tsv tsv (transcript quantifications) transcript quantifications 25.3 MB link
ENCFF814XZP ENCFF814XZP.tsv tsv (transcript quantifications) transcript quantifications 24.9 MB link
ENCFF997NCS ENCFF997NCS.tsv tsv (transcript quantifications) transcript quantifications 25.3 MB link