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29 results for “RNA localization”

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  1. Resources for the Comprehensive Discovery of Functional RNA Elements.

    Molecular cell · 2016 · 61(6): 903-13

    Transcriptome-wide maps of RNA binding protein (RBP)-RNA interactions by immunoprecipitation (IP)-based methods such as RNA IP (RIP) and crosslinking and IP (CLIP) are key starting points for evaluating the molecular roles of the thousands of human RBPs. A significant bottleneck …

    PMID 26990993 DOI ↗

  2. Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development.

    Circulation · 2015 · 131(14): 1278-1290

    Long noncoding RNAs (lncRNAs) have emerged as critical epigenetic regulators with important functions in development and disease. Here, we sought to identify and functionally characterize novel lncRNAs critical for vertebrate development. By relying on human pluripotent stem cell differentiation models, …

    PMID 25739401 DOI ↗

  3. Genome-wide approaches to dissect the roles of RNA binding proteins in translational control: implications for neurological diseases.

    Frontiers in neuroscience · 2012 · 6: 144

    Translational control of messenger RNAs (mRNAs) is a key aspect of neurobiology, defects of which can lead to neurological diseases. In response to stimuli, local translation of mRNAs is activated at synapses to facilitate long-lasting forms of synaptic plasticity, the …

    PMID 23060744 DOI ↗

  4. Inference of splicing regulatory activities by sequence neighborhood analysis.

    PLoS genetics · 2006 · 2(11): e191

    Sequence-specific recognition of nucleic-acid motifs is critical to many cellular processes. We have developed a new and general method called Neighborhood Inference (NI) that predicts sequences with activity in regulating a biochemical process based on the local density of known …

    PMID 17121466 DOI ↗

Datasets 2

GSE106493 GSE · GEO

Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking

Homo sapiens · GPL11154

GSE157467 GSE · GEO

Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress

Homo sapiens · GPL20301

Analyses 1

GSE157467 Processing Pipeline

GSE157467 · 6 steps · RNA-Seq · code_examples

Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress. (2021)