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GSE157467

GSE GEO
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Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress

Organism: Homo sapiens
Platform: GPL20301
Samples: 130
Experiment Types:
Expression profiling by high throughput sequencing Other
Submitted: Sep 04 2020
Last Updated: Mar 21 2022
Status: Public on Aug 01 2021
Contact: Gene,,Yeo (UCSD)

Relations

BioProject: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA661432 SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRP280075

Summary

Neurodegeneration-associated mutations affect the dynamics of transient cytoplasmic stress granule (SG). However, it is unclear if and how aberrant SG behavior is linked to the downstream formation of protein aggregates and other molecular defects that persist after stress subsides. Using subcellular fractionation combined with RNA-seq (CeFra-seq) we characterize the global mRNA localization landscape in human pluripotent stem cell-derived motor neuron (PS-MN). Using CeFra-seq and quantitative proteomics, we find that transient stress leads to a widespread reshaping of mRNA and protein localization that recapitulates key molecular phenotypes of Amyotrophic Lateral Sclerosis (ALS). While the substantial reorganization of the global mRNA localization landscape is largely reversible in wild type PS-MNs, we find that cells harboring ALS-linked mutations in HNRNPA2B1 are unable to recover and display a delayed-onset increase in neuronal cell death in response to stress. Our findings reaffirm the importance of stress-induced molecular mechanisms in the formation of molecular disease pathology of ALS and highlight the importance of targeting SG-relevant molecular mechanisms in the development of therapeutic strategies.

Overall Design

Analysis of global mRNA localization in stem cells, stem cell-derived motor neurons and stem cell-derived motor neurons exposed to cellular stress and/or harboring ALS-associated mutations in HNRNPA2B1

Analysis (6 steps)

View Data Processing
Processing steps for GSE157467
  1. Fastq files were trimmed for adapters using cutadapt
  2. Trimmed reads were aligned to the human genome build hg19 using STAR aligner
  3. seCLIP : Binding region peaks were identified based on read pileup densities (Clipper)
  4. seCLIP : Reproducible peaks were identified by comparing replicate read pileups along binding regions
  5. wiggle files
  6. peak text files

Supplementary Files (8)

GSE157467_G3BP_puro_reproducible_annotated_peaks.bed.gz Download
GSE157467_G3BP_ut_reproducible_annotated_peaks.bed.gz Download
GSE157467_RAW.tar Download
GSE157467_TDP43_puro_reproducible_annotated_peaks.bed.gz Download
GSE157467_TDP43_ut_reproducible_annotated_peaks.bed.gz Download
GSE157467_TIA1_puro_annotated_peaks.bed.gz Download
GSE157467_TIA1_ut_reproducible_annotated_peaks.bed.gz Download
GSE157467_deseq2_normalized_counts.txt.gz Download
GEO Samples (130)
GSM4766652 GSM4766653 GSM4766654 GSM4766655 GSM4766656 GSM4766657 GSM4766658 GSM4766659 GSM4766660 GSM4766661 GSM4766662 GSM4766663 GSM4766664 GSM4766665 GSM4766666 GSM4766667 GSM4766668 GSM4766669 GSM4766670 GSM4766671 GSM4766672 GSM4766673 GSM4766674 GSM4766675 GSM4766676 GSM4766677 GSM4766678 GSM4766679 GSM4766680 GSM4766681 GSM4766682 GSM4766683 GSM4766684 GSM4766685 GSM4766686 GSM4766687 GSM4766688 GSM4766689 GSM4766690 GSM4766691 GSM4766692 GSM4766693 GSM4766694 GSM4766695 GSM4766696 GSM4766697 GSM4766698 GSM4766699 GSM4766700 GSM4766701 GSM4766702 GSM4766703 GSM4766704 GSM4766705 GSM4766706 GSM4766707 GSM4766708 GSM4766709 GSM4766710 GSM4766711 GSM4766712 GSM4766713 GSM4766714 GSM4766715 GSM4766716 GSM4766717 GSM4766718 GSM4766719 GSM4766720 GSM4766721 GSM4766722 GSM4766723 GSM4766724 GSM4766725 GSM4766726 GSM4766727 GSM4766728 GSM4766729 GSM4766730 GSM4766731 GSM4766732 GSM4766733 GSM4766734 GSM4766735 GSM4766736 GSM4766737 GSM4766738 GSM4766739 GSM4766740 GSM4766741 GSM4766742 GSM4766743 GSM4766744 GSM4766745 GSM4766746 GSM4766747 GSM4766748 GSM4766749 GSM4766750 GSM4766751 GSM4766752 GSM4766753 GSM4766754 GSM4766755 GSM4766756 GSM4766757 GSM4766758 GSM4766759 GSM4766760 GSM4766761 GSM4766762 GSM4766763 GSM4766764 GSM4766765 GSM4766766 GSM4766767 GSM4766768 GSM4766769 GSM4766770 GSM4766771 GSM4766772 GSM4766773 GSM4766774 GSM4766775 GSM4766776 GSM4766777 GSM4766778 GSM4766779 GSM4766780 GSM4766781

Dataset Citations (1)

Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress.
PMID 34496257 · 2021 · Cell reports
Sebastian Markmiller, Shashank Sathe, Kari L Server, Thai B Nguyen, Amit Fulzele, Neal Cody, Ashkan Javaherian, Sara Broski, Steven Finkbeiner, Eric J Bennett, Eric Lécuyer, Gene W Yeo

SRA Experiments (130) and Runs (130)

Total: 166384 MB
SRX9074937 SRP280075 RNA-Seq SINGLE
GSM4766700: H1 Motor Neuron Untreated Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322070
BioProject: PRJNA661432
BioSample: SAMN16057708
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Untreated
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588377 22468552 2246855200 773.0 H1_ut_nucl_rep1.fastq.gz, SRR12588377, SRR12588377.lite SRA
SRX9074938 SRP280075 RNA-Seq SINGLE
GSM4766701: H1 Motor Neuron Untreated Nuclear Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322071
BioProject: PRJNA661432
BioSample: SAMN16057707
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Untreated
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588378 26756203 2675620300 921.98 H1_ut_nucl_rep2.fastq.gz, SRR12588378, SRR12588378.lite SRA
SRX9074939 SRP280075 RNA-Seq SINGLE
GSM4766702: H1 Motor Neuron Untreated Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322072
BioProject: PRJNA661432
BioSample: SAMN16057706
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588379 31901056 3190105600 1098.89 H1_ut_total_rep1.fastq.gz, SRR12588379, SRR12588379.lite SRA
SRX9074940 SRP280075 RNA-Seq SINGLE
GSM4766703: H1 Motor Neuron Untreated Total RNA Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322073
BioProject: PRJNA661432
BioSample: SAMN16057705
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588380 27414945 2741494500 947.32 H1_ut_total_rep2.fastq.gz, SRR12588380, SRR12588380.lite SRA
SRX9074941 SRP280075 RNA-Seq SINGLE
GSM4766704: H9 Stem Cell Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322074
BioProject: PRJNA661432
BioSample: SAMN16057704
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hESCs
cell line: H9 ESC line
treatment: Untreated
fraction: Cytoplasm
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588381 13961024 698051200 461.4 H9_ESC_cyto_rep1.fastq.gz, SRR12588381, SRR12588381.lite SRA
SRX9074942 SRP280075 RNA-Seq SINGLE
GSM4766705: H9 Stem Cell Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322075
BioProject: PRJNA661432
BioSample: SAMN16057703
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hESCs
cell line: H9 ESC line
treatment: Untreated
fraction: Insoluble
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588382 15836170 791808500 519.94 H9_ESC_insol_rep1.fastq.gz, SRR12588382, SRR12588382.lite SRA
SRX9074943 SRP280075 RNA-Seq SINGLE
GSM4766706: H9 Stem Cell Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322076
BioProject: PRJNA661432
BioSample: SAMN16057702
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hESCs
cell line: H9 ESC line
treatment: Untreated
fraction: Nucleus
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588383 18559585 927979250 606.65 H9_ESC_nuclei_rep1.fastq.gz, SRR12588383, SRR12588383.lite SRA
SRX9074944 SRP280075 RNA-Seq SINGLE
GSM4766707: H9 Stem Cell Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322077
BioProject: PRJNA661432
BioSample: SAMN16057701
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hESCs
cell line: H9 ESC line
treatment: Untreated
fraction: Total
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588384 12810564 640528200 420.56 H9_ESC_total_rep1.fastq.gz, SRR12588384, SRR12588384.lite SRA
SRX9074945 SRP280075 RNA-Seq SINGLE
GSM4766708: CR463 Line Puromycin Treatment Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322078
BioProject: PRJNA661432
BioSample: SAMN16057700
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Puromycin
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588385 25572996 2582872596 1194.69 insol_CR463_puro_rep1.fastq.gz, SRR12588385, SRR12588385.lite SRA
SRX9074946 SRP280075 RNA-Seq SINGLE
GSM4766709: CR463 Line Puromycin Treatment Insoluble Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322079
BioProject: PRJNA661432
BioSample: SAMN16057699
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Puromycin
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588386 26060551 2632115651 1331.05 insol_CR463_puro_rep2.fastq.gz, SRR12588386, SRR12588386.lite SRA
SRX9074947 SRP280075 RNA-Seq SINGLE
GSM4766710: CR463 Line Recovery Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322080
BioProject: PRJNA661432
BioSample: SAMN16057698
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Recovery
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588387 38923041 3931227141 1939.88 insol_CR463_rec_rep1.fastq.gz, SRR12588387, SRR12588387.lite SRA
SRX9074948 SRP280075 RNA-Seq SINGLE
GSM4766711: CR463 Line Recovery Insoluble Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322081
BioProject: PRJNA661432
BioSample: SAMN16057732
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Recovery
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588388 61832488 6245081288 2966.84 insol_CR463_rec_rep2.fastq.gz, SRR12588388, SRR12588388.lite SRA
SRX9074949 SRP280075 RNA-Seq SINGLE
GSM4766712: CR463 Line Untreated Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322082
BioProject: PRJNA661432
BioSample: SAMN16057659
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Untreated
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588389 39326683 3971994983 1705.22 insol_CR463_ut_rep1.fastq.gz, SRR12588389, SRR12588389.lite SRA
SRX9074950 SRP280075 RNA-Seq SINGLE
GSM4766713: CR463 Line Untreated Insoluble Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322083
BioProject: PRJNA661432
BioSample: SAMN16057658
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Untreated
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588390 43594918 4403086718 2001.42 insol_CR463_ut_rep2.fastq.gz, SRR12588390, SRR12588390.lite SRA
SRX9074951 SRP280075 RNA-Seq SINGLE
GSM4766714: CR464 Line Puromycin Treatment Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322084
BioProject: PRJNA661432
BioSample: SAMN16057657
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Puromycin
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588391 40321261 4072447361 1877.03 insol_CR464_puro_rep1.fastq.gz, SRR12588391, SRR12588391.lite SRA
SRX9074952 SRP280075 RNA-Seq SINGLE
GSM4766715: CR464 Line Puromycin Treatment Insoluble Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322085
BioProject: PRJNA661432
BioSample: SAMN16057656
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Puromycin
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588392 24917957 2516713657 1269.97 insol_CR464_puro_rep2.fastq.gz, SRR12588392, SRR12588392.lite SRA
SRX9074953 SRP280075 RNA-Seq SINGLE
GSM4766716: CR464 Line Recovery Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322086
BioProject: PRJNA661432
BioSample: SAMN16057655
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Recovery
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588393 51127371 5163864471 2538.81 insol_CR464_rec_rep1.fastq.gz, SRR12588393, SRR12588393.lite SRA
SRX9074954 SRP280075 RNA-Seq SINGLE
GSM4766717: CR464 Line Recovery Insoluble Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322087
BioProject: PRJNA661432
BioSample: SAMN16057654
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Recovery
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588394 27814735 2809288235 1390.86 insol_CR464_rec_rep2.fastq.gz, SRR12588394, SRR12588394.lite SRA
SRX9074955 SRP280075 RNA-Seq SINGLE
GSM4766718: CR464 Line Untreated Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322088
BioProject: PRJNA661432
BioSample: SAMN16057653
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Untreated
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588395 23974239 2421398139 1037.93 insol_CR464_ut_rep1.fastq.gz, SRR12588395, SRR12588395.lite SRA
SRX9074956 SRP280075 RNA-Seq SINGLE
GSM4766719: CR464 Line Untreated Insoluble Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322089
BioProject: PRJNA661432
BioSample: SAMN16057652
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Untreated
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588396 43840279 4427868179 2037.71 insol_CR464_ut_rep2.fastq.gz, SRR12588396, SRR12588396.lite SRA
SRX9074957 SRP280075 RNA-Seq SINGLE
GSM4766720: Kin 2-4 Motor Neuron Puromycin Treatment Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322090
BioProject: PRJNA661432
BioSample: SAMN16057651
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Puromycin
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588397 27426514 2742651400 934.97 Kin2-4_puro_cyto_rep1.fastq.gz, SRR12588397, SRR12588397.lite SRA
SRX9074958 SRP280075 RNA-Seq SINGLE
GSM4766721: Kin 2-4 Motor Neuron Puromycin Treatment Cytoplasm Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322091
BioProject: PRJNA661432
BioSample: SAMN16057650
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Puromycin
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588398 26856629 2685662900 920.22 Kin2-4_puro_cyto_rep2.fastq.gz, SRR12588398, SRR12588398.lite SRA
SRX9074959 SRP280075 RNA-Seq SINGLE
GSM4766722: Kin 2-4 Motor Neuron Puromycin Treatment Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322092
BioProject: PRJNA661432
BioSample: SAMN16057649
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Puromycin
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588399 27420928 2742092800 934.82 Kin2-4_puro_insol_rep1.fastq.gz, SRR12588399, SRR12588399.lite SRA
SRX9074960 SRP280075 RNA-Seq SINGLE
GSM4766723: Kin 2-4 Motor Neuron Puromycin Treatment Insoluble Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322093
BioProject: PRJNA661432
BioSample: SAMN16057681
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Puromycin
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588400 29435166 2943516600 1004.71 Kin2-4_puro_insol_rep2.fastq.gz, SRR12588400, SRR12588400.lite SRA
SRX9074961 SRP280075 RNA-Seq SINGLE
GSM4766748: CR463 Line Puromycin Treatment Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322094
BioProject: PRJNA661432
BioSample: SAMN16057617
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588425 40746220 4115368220 1922.17 total_CR463_puro_rep1.fastq.gz, SRR12588425, SRR12588425.lite SRA
SRX9074962 SRP280075 RNA-Seq SINGLE
GSM4766749: CR463 Line Puromycin Treatment Total RNA Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322095
BioProject: PRJNA661432
BioSample: SAMN16057616
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588426 21912206 2213132806 1136.5 total_CR463_puro_rep2.fastq.gz, SRR12588426, SRR12588426.lite SRA
SRX9074963 SRP280075 RNA-Seq SINGLE
GSM4766750: CR463 Line Recovery Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322096
BioProject: PRJNA661432
BioSample: SAMN16057615
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Recovery
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588427 24226216 2446847816 1216.96 total_CR463_rec_rep1.fastq.gz, SRR12588427, SRR12588427.lite SRA
SRX9074964 SRP280075 RNA-Seq SINGLE
GSM4766751: CR463 Line Recovery Total RNA Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322097
BioProject: PRJNA661432
BioSample: SAMN16057648
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Recovery
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588428 47204758 4767680558 2291.31 total_CR463_rec_rep2.fastq.gz, SRR12588428, SRR12588428.lite SRA
SRX9074965 SRP280075 RNA-Seq SINGLE
GSM4766752: CR463 Line Untreated Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322098
BioProject: PRJNA661432
BioSample: SAMN16057647
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588429 44503505 4494854005 1943.29 total_CR463_ut_rep1.fastq.gz, SRR12588429, SRR12588429.lite SRA
SRX9074966 SRP280075 RNA-Seq SINGLE
GSM4766753: CR463 Line Untreated Total RNA Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322099
BioProject: PRJNA661432
BioSample: SAMN16057646
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588430 43151071 4358258171 2019.92 total_CR463_ut_rep2.fastq.gz, SRR12588430, SRR12588430.lite SRA
SRX9074967 SRP280075 RNA-Seq SINGLE
GSM4766754: CR464 Line Puromycin Treatment Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322100
BioProject: PRJNA661432
BioSample: SAMN16057645
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588431 24291070 2453398070 1150.32 total_CR464_puro_rep1.fastq.gz, SRR12588431, SRR12588431.lite SRA
SRX9074968 SRP280075 RNA-Seq SINGLE
GSM4766755: CR464 Line Puromycin Treatment Total RNA Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322101
BioProject: PRJNA661432
BioSample: SAMN16057644
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588432 22736720 2296408720 1178.68 total_CR464_puro_rep2.fastq.gz, SRR12588432, SRR12588432.lite SRA
SRX9074969 SRP280075 RNA-Seq SINGLE
GSM4766756: CR464 Line Recovery Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322102
BioProject: PRJNA661432
BioSample: SAMN16057643
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Recovery
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588433 31827978 3214625778 1543.88 total_CR464_rec_rep1.fastq.gz, SRR12588433, SRR12588433.lite SRA
SRX9074970 SRP280075 RNA-Seq SINGLE
GSM4766757: CR464 Line Recovery Total RNA Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322103
BioProject: PRJNA661432
BioSample: SAMN16057642
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Recovery
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588434 26476170 2674093170 1281.99 total_CR464_rec_rep2.fastq.gz, SRR12588434, SRR12588434.lite SRA
SRX9074971 SRP280075 RNA-Seq SINGLE
GSM4766758: CR464 Line Untreated Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322104
BioProject: PRJNA661432
BioSample: SAMN16057641
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588435 43756304 4419386704 1914.14 total_CR464_ut_rep1.fastq.gz, SRR12588435, SRR12588435.lite SRA
SRX9074972 SRP280075 RNA-Seq SINGLE
GSM4766759: CR464 Line Untreated Total RNA Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322105
BioProject: PRJNA661432
BioSample: SAMN16057640
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588436 36581022 3694683222 1713.03 total_CR464_ut_rep2.fastq.gz, SRR12588436, SRR12588436.lite SRA
SRX9074973 SRP280075 RIP-Seq SINGLE
GSM4766760: CVB Motor Neuron Puromycin Stress TDP43 INPUT Replicate 1; Homo sapiens; RIP-Seq
Sample: SRS7322106
BioProject: PRJNA661432
BioSample: SAMN16057639
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-B hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588437 28587158 2144036850 805.92 CVB_TDP43_puro_input_rep1.fastq.gz, SRR12588437, SRR12588437.lite SRA
SRX9074974 SRP280075 RIP-Seq SINGLE
GSM4766761: CVB Motor Neuron Puromycin Stress TDP43 INPUT Replicate 2; Homo sapiens; RIP-Seq
Sample: SRS7322107
BioProject: PRJNA661432
BioSample: SAMN16057638
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-B hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588438 21514740 1613605500 610.42 CVB_TDP43_puro_input_rep2.fastq.gz, SRR12588438, SRR12588438.lite SRA
SRX9074975 SRP280075 RIP-Seq SINGLE
GSM4766762: CVB Motor Neuron Puromycin Stress TDP43 IP Replicate 1; Homo sapiens; RIP-Seq
Sample: SRS7322108
BioProject: PRJNA661432
BioSample: SAMN16057637
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-B hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588439 74780427 5608532025 2022.82 CVB_TDP43_puro_IP_rep1.fastq.gz, SRR12588439, SRR12588439.lite SRA
SRX9074976 SRP280075 RIP-Seq SINGLE
GSM4766763: CVB Motor Neuron Puromycin Stress TDP43 IP Replicate 2; Homo sapiens; RIP-Seq
Sample: SRS7322109
BioProject: PRJNA661432
BioSample: SAMN16057636
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-B hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588440 98734031 7405052325 2731.62 CVB_TDP43_puro_IP_rep2.fastq.gz, SRR12588440, SRR12588440.lite SRA
SRX9074977 SRP280075 RIP-Seq SINGLE
GSM4766764: CVB Motor Neuron Untreated TDP43 INPUT Replicate 1; Homo sapiens; RIP-Seq
Sample: SRS7322110
BioProject: PRJNA661432
BioSample: SAMN16057635
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-B hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588441 22048768 1653657600 622.11 CVB_TDP43_ut_input_rep1.fastq.gz, SRR12588441, SRR12588441.lite SRA
SRX9074978 SRP280075 RIP-Seq SINGLE
GSM4766765: CVB Motor Neuron Untreated TDP43 INPUT Replicate 2; Homo sapiens; RIP-Seq
Sample: SRS7322111
BioProject: PRJNA661432
BioSample: SAMN16057634
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-B hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588442 27688538 2076640350 789.29 CVB_TDP43_ut_input_rep2.fastq.gz, SRR12588442, SRR12588442.lite SRA
SRX9074979 SRP280075 RIP-Seq SINGLE
GSM4766766: CVB Motor Neuron Untreated TDP43 IP Replicate 1; Homo sapiens; RIP-Seq
Sample: SRS7322112
BioProject: PRJNA661432
BioSample: SAMN16057665
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-B hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588443 53007961 3975597075 1445.38 CVB_TDP43_ut_IP_rep1.fastq.gz, SRR12588443, SRR12588443.lite SRA
SRX9074980 SRP280075 RIP-Seq SINGLE
GSM4766767: CVB Motor Neuron Untreated TDP43 IP Replicate 2; Homo sapiens; RIP-Seq
Sample: SRS7322113
BioProject: PRJNA661432
BioSample: SAMN16057664
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-B hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588444 58234870 4367615250 1595.16 CVB_TDP43_ut_IP_rep2.fastq.gz, SRR12588444, SRR12588444.lite SRA
SRX9074981 SRP280075 RIP-Seq SINGLE
GSM4766768: CVC Motor Neuron Puromycin Stress G3BP INPUT Replicate 1; Homo sapiens; RIP-Seq
Sample: SRS7322114
BioProject: PRJNA661432
BioSample: SAMN16057663
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-C hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588445 55623102 4227355752 1554.91 CVC_G3BP_puro_input_rep1.fastq.gz, SRR12588445, SRR12588445.lite SRA
SRX9074982 SRP280075 RIP-Seq SINGLE
GSM4766769: CVC Motor Neuron Puromycin Stress G3BP INPUT Replicate 2; Homo sapiens; RIP-Seq
Sample: SRS7322115
BioProject: PRJNA661432
BioSample: SAMN16057662
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-C hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588446 78960724 6001015024 2139.47 CVC_G3BP_puro_input_rep2.fastq.gz, SRR12588446, SRR12588446.lite SRA
SRX9074983 SRP280075 RIP-Seq SINGLE
GSM4766770: CVC Motor Neuron Puromycin Stress G3BP IP Replicate 1; Homo sapiens; RIP-Seq
Sample: SRS7322116
BioProject: PRJNA661432
BioSample: SAMN16057661
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-C hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588447 45747324 3476796624 1270.34 CVC_G3BP_puro_IP_rep1.fastq.gz, SRR12588447, SRR12588447.lite SRA
SRX9074984 SRP280075 RIP-Seq SINGLE
GSM4766771: CVC Motor Neuron Puromycin Stress G3BP IP Replicate 2; Homo sapiens; RIP-Seq
Sample: SRS7322117
BioProject: PRJNA661432
BioSample: SAMN16057660
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-C hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588448 75102968 5707825568 2019.57 CVC_G3BP_puro_IP_rep2.fastq.gz, SRR12588448, SRR12588448.lite SRA
SRX9074985 SRP280075 RIP-Seq SINGLE
GSM4766772: CVC Motor Neuron Untreated G3BP INPUT Replicate 1; Homo sapiens; RIP-Seq
Sample: SRS7322118
BioProject: PRJNA661432
BioSample: SAMN16057633
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-C hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588449 65532732 4980487632 1823.56 CVC_G3BP_ut_input_rep1.fastq.gz, SRR12588449, SRR12588449.lite SRA
SRX9074986 SRP280075 RIP-Seq SINGLE
GSM4766773: CVC Motor Neuron Untreated G3BP INPUT Replicate 2; Homo sapiens; RIP-Seq
Sample: SRS7322119
BioProject: PRJNA661432
BioSample: SAMN16057632
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-C hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588450 61746484 4692732784 1685.74 CVC_G3BP_ut_input_rep2.fastq.gz, SRR12588450, SRR12588450.lite SRA
SRX9074987 SRP280075 RIP-Seq SINGLE
GSM4766774: CVC Motor Neuron Untreated G3BP IP Replicate 1; Homo sapiens; RIP-Seq
Sample: SRS7322120
BioProject: PRJNA661432
BioSample: SAMN16057631
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-C hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588451 62658510 4762046760 1755.1 CVC_G3BP_ut_IP_rep1.fastq.gz, SRR12588451, SRR12588451.lite SRA
SRX9074988 SRP280075 RIP-Seq SINGLE
GSM4766775: CVC Motor Neuron Untreated G3BP IP Replicate 2; Homo sapiens; RIP-Seq
Sample: SRS7322121
BioProject: PRJNA661432
BioSample: SAMN16057630
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CV-C hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588452 67009334 5092709384 1796.0 CVC_G3BP_ut_IP_rep2.fastq.gz, SRR12588452, SRR12588452.lite SRA
SRX9074989 SRP280075 RIP-Seq PAIRED
GSM4766776: H1 Motor Neuron Untreated TIA1 INPUT Replicate 1 Read 1; Homo sapiens; RIP-Seq
Sample: SRS7322122
BioProject: PRJNA661432
BioSample: SAMN16057629
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: ESC-derived motor neurons
cell line: H1 ESC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588453 32865045 6573009000 2366.76 TIA1_MN_input_rep1_R1.fastq.gz, TIA1_MN_input_rep1_R2.fastq.gz, SRR12… SRA
SRX9074990 SRP280075 RIP-Seq PAIRED
GSM4766777: H1 Motor Neuron Untreated TIA1 INPUT Replicate 2 Read 1; Homo sapiens; RIP-Seq
Sample: SRS7322123
BioProject: PRJNA661432
BioSample: SAMN16057628
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: ESC-derived motor neurons
cell line: H1 ESC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588454 29433335 5886667000 2178.77 TIA1_MN_input_rep2_R1.fastq.gz, TIA1_MN_input_rep2_R2.fastq.gz, SRR12… SRA
SRX9074991 SRP280075 RIP-Seq PAIRED
GSM4766778: H1 Motor Neuron Untreated TIA1 IP Replicate 1 Read 1; Homo sapiens; RIP-Seq
Sample: SRS7322124
BioProject: PRJNA661432
BioSample: SAMN16057627
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: ESC-derived motor neurons
cell line: H1 ESC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588455 39011152 7802230400 2836.83 TIA1_MN_IP_rep1_R1.fastq.gz, TIA1_MN_IP_rep1_R2.fastq.gz, SRR12588455… SRA
SRX9074992 SRP280075 RIP-Seq PAIRED
GSM4766779: H1 Motor Neuron Untreated TIA1 IP Replicate 2 Read 1; Homo sapiens; RIP-Seq
Sample: SRS7322125
BioProject: PRJNA661432
BioSample: SAMN16057626
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: ESC-derived motor neurons
cell line: H1 ESC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588456 32521641 6504328200 2403.95 TIA1_MN_IP_rep2_R1.fastq.gz, TIA1_MN_IP_rep2_R2.fastq.gz, SRR12588456… SRA
SRX9074993 SRP280075 RIP-Seq PAIRED
GSM4766780: H1 Motor Neuron Puromycin Stress TIA1 INPUT Replicate 1 Read 1; Homo sapiens; RIP-Seq
Sample: SRS7322126
BioProject: PRJNA661432
BioSample: SAMN16057625
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: ESC-derived motor neurons
cell line: H1 ESC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588457 85883210 17176642000 6252.85 TIA1_Stressed_MN_input_rep1_R1.fastq.gz, TIA1_Stressed_MN_input_rep1_… SRA
SRX9074994 SRP280075 RIP-Seq PAIRED
GSM4766781: H1 Motor Neuron Puromycin Stress TIA1 IP Replicate 1 Read 1; Homo sapiens; RIP-Seq
Sample: SRS7322127
BioProject: PRJNA661432
BioSample: SAMN16057624
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: ESC-derived motor neurons
cell line: H1 ESC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588458 97579712 19515942400 7064.8 TIA1_Stressed_MN_IP_rep1_R1.fastq.gz, TIA1_Stressed_MN_IP_rep1_R2.fas… SRA
SRX9074995 SRP280075 RNA-Seq SINGLE
GSM4766652: CVB Stem Cell Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322128
BioProject: PRJNA661432
BioSample: SAMN16057731
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hiPSCs
cell line: CV-B hiPSC line
treatment: Untreated
fraction: Cytoplasm
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588329 8611180 430559000 286.28 CVB_iPSC_cyto_rep1.fastq.gz, SRR12588329, SRR12588329.lite SRA
SRX9074996 SRP280075 RNA-Seq SINGLE
GSM4766653: CVB Stem Cell Cytoplasm Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322129
BioProject: PRJNA661432
BioSample: SAMN16057730
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hiPSCs
cell line: CV-B hiPSC line
treatment: Untreated
fraction: Cytoplasm
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588330 15120462 756023100 503.18 CVB_iPSC_cyto_rep2.fastq.gz, SRR12588330, SRR12588330.lite SRA
SRX9074997 SRP280075 RNA-Seq SINGLE
GSM4766654: CVB Stem Cell Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322130
BioProject: PRJNA661432
BioSample: SAMN16057729
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hiPSCs
cell line: CV-B hiPSC line
treatment: Untreated
fraction: Insoluble
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588331 16000615 800030750 528.34 CVB_iPSC_insol_rep1.fastq.gz, SRR12588331, SRR12588331.lite SRA
SRX9074998 SRP280075 RNA-Seq SINGLE
GSM4766655: CVB Stem Cell Insoluble Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322131
BioProject: PRJNA661432
BioSample: SAMN16057728
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hiPSCs
cell line: CV-B hiPSC line
treatment: Untreated
fraction: Insoluble
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588332 17750027 887501350 584.54 CVB_iPSC_insol_rep2.fastq.gz, SRR12588332, SRR12588332.lite SRA
SRX9074999 SRP280075 RNA-Seq SINGLE
GSM4766656: CVB Stem Cell Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322132
BioProject: PRJNA661432
BioSample: SAMN16057727
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hiPSCs
cell line: CV-B hiPSC line
treatment: Untreated
fraction: Nucleus
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588333 11893007 594650350 393.92 CVB_iPSC_nuclei_rep1.fastq.gz, SRR12588333, SRR12588333.lite SRA
SRX9075000 SRP280075 RNA-Seq SINGLE
GSM4766657: CVB Stem Cell Nuclear Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322133
BioProject: PRJNA661432
BioSample: SAMN16057726
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hiPSCs
cell line: CV-B hiPSC line
treatment: Untreated
fraction: Nucleus
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588334 19836570 991828500 653.45 CVB_iPSC_nuclei_rep2.fastq.gz, SRR12588334, SRR12588334.lite SRA
SRX9075001 SRP280075 RNA-Seq SINGLE
GSM4766658: CVB Stem Cell Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322134
BioProject: PRJNA661432
BioSample: SAMN16057725
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hiPSCs
cell line: CV-B hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588335 33756418 1687820900 1123.56 CVB_iPSC_total_rep1.fastq.gz, SRR12588335, SRR12588335.lite SRA
SRX9075002 SRP280075 RNA-Seq SINGLE
GSM4766659: CVB Stem Cell Total RNA Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322135
BioProject: PRJNA661432
BioSample: SAMN16057724
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hiPSCs
cell line: CV-B hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588336 18439456 921972800 613.21 CVB_iPSC_total_rep2.fastq.gz, SRR12588336, SRR12588336.lite SRA
SRX9075003 SRP280075 RNA-Seq SINGLE
GSM4766660: CR463 Line Puromycin Treatment Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322136
BioProject: PRJNA661432
BioSample: SAMN16057723
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Puromycin
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588337 24477932 2472271132 1161.6 cyto_CR463_puro_rep1.fastq.gz, SRR12588337, SRR12588337.lite SRA
SRX9075004 SRP280075 RNA-Seq SINGLE
GSM4766661: CR463 Line Puromycin Treatment Cytoplasm Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322137
BioProject: PRJNA661432
BioSample: SAMN16057722
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Puromycin
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588338 24002663 2424268963 1244.01 cyto_CR463_puro_rep2.fastq.gz, SRR12588338, SRR12588338.lite SRA
SRX9075005 SRP280075 RNA-Seq SINGLE
GSM4766662: CR463 Line Recovery Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322138
BioProject: PRJNA661432
BioSample: SAMN16057721
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Recovery
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588339 32510674 3283578074 1637.59 cyto_CR463_rec_rep1.fastq.gz, SRR12588339, SRR12588339.lite SRA
SRX9075006 SRP280075 RNA-Seq SINGLE
GSM4766663: CR463 Line Recovery Cytoplasm Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322139
BioProject: PRJNA661432
BioSample: SAMN16057720
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Recovery
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588340 32596113 3292207413 1598.36 cyto_CR463_rec_rep2.fastq.gz, SRR12588340, SRR12588340.lite SRA
SRX9075007 SRP280075 RNA-Seq SINGLE
GSM4766664: CR463 Line Untreated Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322140
BioProject: PRJNA661432
BioSample: SAMN16057719
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Untreated
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588341 42104642 4252568842 1844.7 cyto_CR463_ut_rep1.fastq.gz, SRR12588341, SRR12588341.lite SRA
SRX9075008 SRP280075 RNA-Seq SINGLE
GSM4766665: CR463 Line Untreated Cytoplasm Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322141
BioProject: PRJNA661432
BioSample: SAMN16057718
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Untreated
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588342 32118391 3243957491 1499.68 cyto_CR463_ut_rep2.fastq.gz, SRR12588342, SRR12588342.lite SRA
SRX9075009 SRP280075 RNA-Seq SINGLE
GSM4766666: CR464 Line Puromycin Treatment Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322142
BioProject: PRJNA661432
BioSample: SAMN16057717
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Puromycin
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588343 46820785 4728899285 2226.35 cyto_CR464_puro_rep1.fastq.gz, SRR12588343, SRR12588343.lite SRA
SRX9075010 SRP280075 RNA-Seq SINGLE
GSM4766667: CR464 Line Puromycin Treatment Cytoplasm Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322143
BioProject: PRJNA661432
BioSample: SAMN16057716
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Puromycin
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588344 20082819 2028364719 1041.41 cyto_CR464_puro_rep2.fastq.gz, SRR12588344, SRR12588344.lite SRA
SRX9075011 SRP280075 RNA-Seq SINGLE
GSM4766668: CR464 Line Recovery Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322144
BioProject: PRJNA661432
BioSample: SAMN16057715
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Recovery
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588345 29525700 2982095700 1493.21 cyto_CR464_rec_rep1.fastq.gz, SRR12588345, SRR12588345.lite SRA
SRX9075012 SRP280075 RNA-Seq SINGLE
GSM4766669: CR464 Line Recovery Cytoplasm Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322145
BioProject: PRJNA661432
BioSample: SAMN16057714
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Recovery
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588346 28619152 2890534352 1400.47 cyto_CR464_rec_rep2.fastq.gz, SRR12588346, SRR12588346.lite SRA
SRX9075013 SRP280075 RNA-Seq SINGLE
GSM4766670: CR464 Line Untreated Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322146
BioProject: PRJNA661432
BioSample: SAMN16057744
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Untreated
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588347 24321861 2456507961 1067.39 cyto_CR464_ut_rep1.fastq.gz, SRR12588347, SRR12588347.lite SRA
SRX9075014 SRP280075 RNA-Seq SINGLE
GSM4766671: CR464 Line Untreated Cytoplasm Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322147
BioProject: PRJNA661432
BioSample: SAMN16057743
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Untreated
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588348 18724261 1891150361 876.41 cyto_CR464_ut_rep2.fastq.gz, SRR12588348, SRR12588348.lite SRA
SRX9075015 SRP280075 RNA-Seq SINGLE
GSM4766672: H1 Stem Cell Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322148
BioProject: PRJNA661432
BioSample: SAMN16057742
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hESCs
cell line: H1 ESC line
treatment: Untreated
fraction: Cytoplasm
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588349 10596434 529821700 343.7 H1_ESC_cyto_rep1.fastq.gz, SRR12588349, SRR12588349.lite SRA
SRX9075016 SRP280075 RNA-Seq SINGLE
GSM4766673: H1 Stem Cell Cytoplasm Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322149
BioProject: PRJNA661432
BioSample: SAMN16057741
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hESCs
cell line: H1 ESC line
treatment: Untreated
fraction: Cytoplasm
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588350 13804944 690247200 455.88 H1_ESC_cyto_rep2.fastq.gz, SRR12588350, SRR12588350.lite SRA
SRX9075017 SRP280075 RNA-Seq SINGLE
GSM4766674: H1 Stem Cell Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322150
BioProject: PRJNA661432
BioSample: SAMN16057740
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hESCs
cell line: H1 ESC line
treatment: Untreated
fraction: Insoluble
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588351 17416648 870832400 575.74 H1_ESC_insol_rep1.fastq.gz, SRR12588351, SRR12588351.lite SRA
SRX9075018 SRP280075 RNA-Seq SINGLE
GSM4766675: H1 Stem Cell Insoluble Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322151
BioProject: PRJNA661432
BioSample: SAMN16057739
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hESCs
cell line: H1 ESC line
treatment: Untreated
fraction: Insoluble
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588352 16965450 848272500 562.64 H1_ESC_insol_rep2.fastq.gz, SRR12588352, SRR12588352.lite SRA
SRX9075019 SRP280075 RNA-Seq SINGLE
GSM4766676: H1 Stem Cell Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322152
BioProject: PRJNA661432
BioSample: SAMN16057738
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hESCs
cell line: H1 ESC line
treatment: Untreated
fraction: Nucleus
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588353 13053434 652671700 418.79 H1_ESC_nuclei_rep1.fastq.gz, SRR12588353, SRR12588353.lite SRA
SRX9075020 SRP280075 RNA-Seq SINGLE
GSM4766677: H1 Stem Cell Nuclear Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322153
BioProject: PRJNA661432
BioSample: SAMN16057737
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hESCs
cell line: H1 ESC line
treatment: Untreated
fraction: Nucleus
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588354 16130255 806512750 528.51 H1_ESC_nuclei_rep2.fastq.gz, SRR12588354, SRR12588354.lite SRA
SRX9075021 SRP280075 RNA-Seq SINGLE
GSM4766678: H1 Stem Cell Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322154
BioProject: PRJNA661432
BioSample: SAMN16057736
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hESCs
cell line: H1 ESC line
treatment: Untreated
fraction: Total
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588355 14513912 725695600 467.38 H1_ESC_total_rep1.fastq.gz, SRR12588355, SRR12588355.lite SRA
SRX9075022 SRP280075 RNA-Seq SINGLE
GSM4766679: H1 Stem Cell Total RNA Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322155
BioProject: PRJNA661432
BioSample: SAMN16057735
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: stem cells
cell type: hESCs
cell line: H1 ESC line
treatment: Untreated
fraction: Total
Original files (1)
stem cells
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588356 15031221 751561050 494.14 H1_ESC_total_rep2.fastq.gz, SRR12588356, SRR12588356.lite SRA
SRX9075023 SRP280075 RNA-Seq SINGLE
GSM4766680: H1 Motor Neuron Puromycin Treatment Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322156
BioProject: PRJNA661432
BioSample: SAMN16057734
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Puromycin
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588357 21786512 2178651200 732.38 H1_puro1_cyto_rep1.fastq.gz, SRR12588357, SRR12588357.lite SRA
SRX9075024 SRP280075 RNA-Seq SINGLE
GSM4766681: H1 Motor Neuron Puromycin Treatment Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322157
BioProject: PRJNA661432
BioSample: SAMN16057733
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Puromycin
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588358 32299927 3229992700 1084.17 H1_puro1_insol_rep1.fastq.gz, SRR12588358, SRR12588358.lite SRA
SRX9075025 SRP280075 RNA-Seq SINGLE
GSM4766682: H1 Motor Neuron Puromycin Treatment Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322158
BioProject: PRJNA661432
BioSample: SAMN16057694
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Puromycin
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588359 19638189 1963818900 680.76 H1_puro1_nucl_rep1.fastq.gz, SRR12588359, SRR12588359.lite SRA
SRX9075026 SRP280075 RNA-Seq SINGLE
GSM4766683: H1 Motor Neuron Puromycin Treatment Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322159
BioProject: PRJNA661432
BioSample: SAMN16057693
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588360 10306901 1030690100 391.07 H1_puro1_total_rep1.fastq.gz, SRR12588360, SRR12588360.lite SRA
SRX9075027 SRP280075 RNA-Seq SINGLE
GSM4766684: H1 Motor Neuron Puromycin Treatment Cytoplasm Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322160
BioProject: PRJNA661432
BioSample: SAMN16057692
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Puromycin
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588361 27605530 2760553000 929.99 H1_puro_cyto_rep2.fastq.gz, SRR12588361, SRR12588361.lite SRA
SRX9075028 SRP280075 RNA-Seq SINGLE
GSM4766685: H1 Motor Neuron Puromycin Treatment Insoluble Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322161
BioProject: PRJNA661432
BioSample: SAMN16057691
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Puromycin
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588362 31763104 3176310400 1067.86 H1_puro_insol_rep2.fastq.gz, SRR12588362, SRR12588362.lite SRA
SRX9075029 SRP280075 RNA-Seq SINGLE
GSM4766686: H1 Motor Neuron Puromycin Treatment Nuclear Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322162
BioProject: PRJNA661432
BioSample: SAMN16057690
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Puromycin
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588363 23965369 2396536900 828.37 H1_puro_nucl_rep2.fastq.gz, SRR12588363, SRR12588363.lite SRA
SRX9075030 SRP280075 RNA-Seq SINGLE
GSM4766687: H1 Motor Neuron Puromycin Treatment Total RNA Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322163
BioProject: PRJNA661432
BioSample: SAMN16057689
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588364 27719492 2771949200 958.54 H1_puro_total_rep2.fastq.gz, SRR12588364, SRR12588364.lite SRA
SRX9075031 SRP280075 RNA-Seq SINGLE
GSM4766688: H1 Motor Neuron Recovery Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322164
BioProject: PRJNA661432
BioSample: SAMN16057688
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Recovery
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588365 23014614 2301461400 774.29 H1_rec_cyto_rep1.fastq.gz, SRR12588365, SRR12588365.lite SRA
SRX9075032 SRP280075 RNA-Seq SINGLE
GSM4766689: H1 Motor Neuron Recovery Cytoplasm Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322165
BioProject: PRJNA661432
BioSample: SAMN16057687
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Recovery
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588366 21451434 2145143400 720.74 H1_rec_cyto_rep2.fastq.gz, SRR12588366, SRR12588366.lite SRA
SRX9075033 SRP280075 RNA-Seq SINGLE
GSM4766690: H1 Motor Neuron Recovery Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322166
BioProject: PRJNA661432
BioSample: SAMN16057686
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Recovery
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588367 28699436 2869943600 962.67 H1_rec_insol_rep1.fastq.gz, SRR12588367, SRR12588367.lite SRA
SRX9075034 SRP280075 RNA-Seq SINGLE
GSM4766691: H1 Motor Neuron Recovery Insoluble Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322167
BioProject: PRJNA661432
BioSample: SAMN16057685
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Recovery
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588368 29175728 2917572800 982.15 H1_rec_insol_rep2.fastq.gz, SRR12588368, SRR12588368.lite SRA
SRX9075035 SRP280075 RNA-Seq SINGLE
GSM4766692: H1 Motor Neuron Recovery Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322168
BioProject: PRJNA661432
BioSample: SAMN16057684
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Recovery
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588369 6867328 686732800 256.84 H1_rec_nucl_rep1.fastq.gz, SRR12588369, SRR12588369.lite SRA
SRX9075036 SRP280075 RNA-Seq SINGLE
GSM4766693: H1 Motor Neuron Recovery Nuclear Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322169
BioProject: PRJNA661432
BioSample: SAMN16057683
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Recovery
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588370 24099290 2409929000 813.92 H1_rec_nucl_rep2.fastq.gz, SRR12588370, SRR12588370.lite SRA
SRX9075037 SRP280075 RNA-Seq SINGLE
GSM4766694: H1 Motor Neuron Recovery Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322170
BioProject: PRJNA661432
BioSample: SAMN16057682
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Recovery
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588371 29696035 2969603500 996.29 H1_rec_total_rep1.fastq.gz, SRR12588371, SRR12588371.lite SRA
SRX9075038 SRP280075 RNA-Seq SINGLE
GSM4766695: H1 Motor Neuron Recovery Total RNA Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322171
BioProject: PRJNA661432
BioSample: SAMN16057713
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Recovery
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588372 27629132 2762913200 929.54 H1_rec_total_rep2.fastq.gz, SRR12588372, SRR12588372.lite SRA
SRX9075039 SRP280075 RNA-Seq SINGLE
GSM4766696: H1 Motor Neuron Untreated Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322172
BioProject: PRJNA661432
BioSample: SAMN16057712
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Untreated
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588373 4764998 476499800 179.04 H1_ut_cyto_rep1.fastq.gz, SRR12588373, SRR12588373.lite SRA
SRX9075040 SRP280075 RNA-Seq SINGLE
GSM4766697: H1 Motor Neuron Untreated Cytoplasm Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322173
BioProject: PRJNA661432
BioSample: SAMN16057711
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Untreated
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588374 24440449 2444044900 826.4 H1_ut_cyto_rep2.fastq.gz, SRR12588374, SRR12588374.lite SRA
SRX9075041 SRP280075 RNA-Seq SINGLE
GSM4766698: H1 Motor Neuron Untreated Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322174
BioProject: PRJNA661432
BioSample: SAMN16057710
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Untreated
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588375 33276192 3327619200 1147.29 H1_ut_insol_rep1.fastq.gz, SRR12588375, SRR12588375.lite SRA
SRX9075042 SRP280075 RNA-Seq SINGLE
GSM4766699: H1 Motor Neuron Untreated Insoluble Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322175
BioProject: PRJNA661432
BioSample: SAMN16057709
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: hESC-derived motor neurons
cell line: H1 ESC line
treatment: Untreated
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588376 19481929 1948192900 668.96 H1_ut_insol_rep2.fastq.gz, SRR12588376, SRR12588376.lite SRA
SRX9075043 SRP280075 RNA-Seq SINGLE
GSM4766724: Kin 2-4 Motor Neuron Puromycin Treatment Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322176
BioProject: PRJNA661432
BioSample: SAMN16057680
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Puromycin
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588401 30434299 3043429900 1065.37 Kin2-4_puro_nucl_rep1.fastq.gz, SRR12588401, SRR12588401.lite SRA
SRX9075044 SRP280075 RNA-Seq SINGLE
GSM4766725: Kin 2-4 Motor Neuron Puromycin Treatment Nuclear Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322177
BioProject: PRJNA661432
BioSample: SAMN16057679
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Puromycin
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588402 23211138 2321113800 814.03 Kin2-4_puro_nucl_rep2.fastq.gz, SRR12588402, SRR12588402.lite SRA
SRX9075045 SRP280075 RNA-Seq SINGLE
GSM4766726: Kin 2-4 Motor Neuron Puromycin Treatment Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322178
BioProject: PRJNA661432
BioSample: SAMN16057678
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588403 8890057 889005700 340.86 Kin2-4_puro_total_rep1.fastq.gz, SRR12588403, SRR12588403.lite SRA
SRX9075046 SRP280075 RNA-Seq SINGLE
GSM4766727: Kin 2-4 Motor Neuron Puromycin Treatment Total RNA Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322179
BioProject: PRJNA661432
BioSample: SAMN16057677
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Puromycin
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588404 30672077 3067207700 1075.4 Kin2-4_puro_total_rep2.fastq.gz, SRR12588404, SRR12588404.lite SRA
SRX9075047 SRP280075 RNA-Seq SINGLE
GSM4766728: Kin 2-4 Motor Neuron Untreated Cytoplasm Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322180
BioProject: PRJNA661432
BioSample: SAMN16057676
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Untreated
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588405 6456461 645646100 245.54 Kin2-4_ut_cyto_rep1.fastq.gz, SRR12588405, SRR12588405.lite SRA
SRX9075048 SRP280075 RNA-Seq SINGLE
GSM4766729: Kin 2-4 Motor Neuron Untreated Cytoplasm Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322181
BioProject: PRJNA661432
BioSample: SAMN16057675
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Untreated
fraction: Cytoplasm
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588406 23362024 2336202400 802.75 Kin2-4_ut_cyto_rep2.fastq.gz, SRR12588406, SRR12588406.lite SRA
SRX9075049 SRP280075 RNA-Seq SINGLE
GSM4766730: Kin 2-4 Motor Neuron Untreated Insoluble Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322182
BioProject: PRJNA661432
BioSample: SAMN16057674
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Untreated
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588407 25663631 2566363100 903.15 Kin2-4_ut_insol_rep1.fastq.gz, SRR12588407, SRR12588407.lite SRA
SRX9075050 SRP280075 RNA-Seq SINGLE
GSM4766731: Kin 2-4 Motor Neuron Untreated Insoluble Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322183
BioProject: PRJNA661432
BioSample: SAMN16057673
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Untreated
fraction: Insoluble
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588408 22660873 2266087300 789.77 Kin2-4_ut_insol_rep2.fastq.gz, SRR12588408, SRR12588408.lite SRA
SRX9075051 SRP280075 RNA-Seq SINGLE
GSM4766732: Kin 2-4 Motor Neuron Untreated Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322184
BioProject: PRJNA661432
BioSample: SAMN16057672
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Untreated
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588409 26189809 2618980900 912.85 Kin2-4_ut_nucl_rep1.fastq.gz, SRR12588409, SRR12588409.lite SRA
SRX9075052 SRP280075 RNA-Seq SINGLE
GSM4766733: Kin 2-4 Motor Neuron Untreated Nuclear Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322185
BioProject: PRJNA661432
BioSample: SAMN16057671
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Untreated
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588410 30278686 3027868600 1056.81 Kin2-4_ut_nucl_rep2.fastq.gz, SRR12588410, SRR12588410.lite SRA
SRX9075053 SRP280075 RNA-Seq SINGLE
GSM4766734: Kin 2-4 Motor Neuron Untreated Total RNA Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322186
BioProject: PRJNA661432
BioSample: SAMN16057670
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588411 32645860 3264586000 1135.28 Kin2-4_ut_total_rep1.fastq.gz, SRR12588411, SRR12588411.lite SRA
SRX9075054 SRP280075 RNA-Seq SINGLE
GSM4766735: Kin 2-4 Motor Neuron Untreated Total RNA Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322187
BioProject: PRJNA661432
BioSample: SAMN16057669
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: Kin2ALS4 hiPSC line
treatment: Untreated
fraction: Total
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588412 23361928 2336192800 817.92 Kin2-4_ut_total_rep2.fastq.gz, SRR12588412, SRR12588412.lite SRA
SRX9075055 SRP280075 RNA-Seq SINGLE
GSM4766736: CR463 Line Puromycin Treatment Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322188
BioProject: PRJNA661432
BioSample: SAMN16057668
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Puromycin
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588413 19757205 1995477705 951.71 nuc_CR463_puro_rep1.fastq.gz, SRR12588413, SRR12588413.lite SRA
SRX9075056 SRP280075 RNA-Seq SINGLE
GSM4766737: CR463 Line Puromycin Treatment Nuclear Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322189
BioProject: PRJNA661432
BioSample: SAMN16057667
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Puromycin
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588414 49492735 4998766235 2587.43 nuc_CR463_puro_rep2.fastq.gz, SRR12588414, SRR12588414.lite SRA
SRX9075057 SRP280075 RNA-Seq SINGLE
GSM4766738: CR463 Line Recovery Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322190
BioProject: PRJNA661432
BioSample: SAMN16057666
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Recovery
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588415 12704832 1283188032 645.64 nuc_CR463_rec_rep1.fastq.gz, SRR12588415, SRR12588415.lite SRA
SRX9075058 SRP280075 RNA-Seq SINGLE
GSM4766739: CR463 Line Recovery Nuclear Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322191
BioProject: PRJNA661432
BioSample: SAMN16057697
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Recovery
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588416 21951797 2217131497 1077.85 nuc_CR463_rec_rep2.fastq.gz, SRR12588416, SRR12588416.lite SRA
SRX9075059 SRP280075 RNA-Seq SINGLE
GSM4766740: CR463 Line Untreated Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322192
BioProject: PRJNA661432
BioSample: SAMN16057696
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Untreated
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588417 42754183 4318172483 1902.44 nuc_CR463_ut_rep1.fastq.gz, SRR12588417, SRR12588417.lite SRA
SRX9075060 SRP280075 RNA-Seq SINGLE
GSM4766741: CR463 Line Untreated Nuclear Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322193
BioProject: PRJNA661432
BioSample: SAMN16057695
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR463.4 hiPSC line
treatment: Untreated
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588418 25601167 2585717867 1228.69 nuc_CR463_ut_rep2.fastq.gz, SRR12588418, SRR12588418.lite SRA
SRX9075061 SRP280075 RNA-Seq SINGLE
GSM4766742: CR464 Line Puromycin Treatment Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322194
BioProject: PRJNA661432
BioSample: SAMN16057623
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Puromycin
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588419 49518639 5001382539 2382.51 nuc_CR464_puro_rep1.fastq.gz, SRR12588419, SRR12588419.lite SRA
SRX9075062 SRP280075 RNA-Seq SINGLE
GSM4766743: CR464 Line Puromycin Treatment Nuclear Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322195
BioProject: PRJNA661432
BioSample: SAMN16057622
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Puromycin
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588420 21718465 2193564965 1136.78 nuc_CR464_puro_rep2.fastq.gz, SRR12588420, SRR12588420.lite SRA
SRX9075063 SRP280075 RNA-Seq SINGLE
GSM4766744: CR464 Line Recovery Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322196
BioProject: PRJNA661432
BioSample: SAMN16057621
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Recovery
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588421 23439433 2367382733 1188.99 nuc_CR464_rec_rep1.fastq.gz, SRR12588421, SRR12588421.lite SRA
SRX9075064 SRP280075 RNA-Seq SINGLE
GSM4766745: CR464 Line Recovery Nuclear Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322197
BioProject: PRJNA661432
BioSample: SAMN16057620
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Recovery
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588422 26948435 2721791935 1326.88 nuc_CR464_rec_rep2.fastq.gz, SRR12588422, SRR12588422.lite SRA
SRX9075065 SRP280075 RNA-Seq SINGLE
GSM4766746: CR464 Line Untreated Nuclear Fraction Replicate 1; Homo sapiens; RNA-Seq
Sample: SRS7322198
BioProject: PRJNA661432
BioSample: SAMN16057619
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Untreated
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588423 24240927 2448333627 1080.74 nuc_CR464_ut_rep1.fastq.gz, SRR12588423, SRR12588423.lite SRA
SRX9075066 SRP280075 RNA-Seq SINGLE
GSM4766747: CR464 Line Untreated Nuclear Fraction Replicate 2; Homo sapiens; RNA-Seq
Sample: SRS7322199
BioProject: PRJNA661432
BioSample: SAMN16057618
Platform: ILLUMINA
Instrument: Illumina HiSeq 4000
Organism: Homo sapiens
Sample attributes
source_name: motor neurons
cell type: iPSC-derived motor neurons
cell line: CR464.2 hiPSC line
treatment: Untreated
fraction: Nucleus
Original files (1)
motor neurons
Runs (1)
Run Spots Bases Size (MB) Files Link
SRR12588424 30421193 3072540493 1439.33 nuc_CR464_ut_rep2.fastq.gz, SRR12588424, SRR12588424.lite SRA

Linked Publications (2)

Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis.
Acta neuropathologica · 2022
Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress.
Cell reports · 2021

Data Files (130)

Accession File Name Stored Type Output Type Mapping Assembly Size Download
— CVB_TDP43_puro_input_rep1.fastq.gz RIP-Seq 805.9 MB link
— CVB_TDP43_puro_input_rep2.fastq.gz RIP-Seq 610.4 MB link
— CVB_TDP43_puro_IP_rep1.fastq.gz RIP-Seq 2.0 GB link
— CVB_TDP43_puro_IP_rep2.fastq.gz RIP-Seq 2.7 GB link
— CVB_TDP43_ut_input_rep1.fastq.gz RIP-Seq 622.1 MB link
— CVB_TDP43_ut_input_rep2.fastq.gz RIP-Seq 789.3 MB link
— CVB_TDP43_ut_IP_rep1.fastq.gz RIP-Seq 1.4 GB link
— CVB_TDP43_ut_IP_rep2.fastq.gz RIP-Seq 1.6 GB link
— CVC_G3BP_puro_input_rep1.fastq.gz RIP-Seq 1.5 GB link
— CVC_G3BP_puro_input_rep2.fastq.gz RIP-Seq 2.1 GB link
— CVC_G3BP_puro_IP_rep1.fastq.gz RIP-Seq 1.2 GB link
— CVC_G3BP_puro_IP_rep2.fastq.gz RIP-Seq 2.0 GB link
— CVC_G3BP_ut_input_rep1.fastq.gz RIP-Seq 1.8 GB link
— CVC_G3BP_ut_input_rep2.fastq.gz RIP-Seq 1.6 GB link
— CVC_G3BP_ut_IP_rep1.fastq.gz RIP-Seq 1.7 GB link
— CVC_G3BP_ut_IP_rep2.fastq.gz RIP-Seq 1.8 GB link
— TIA1_MN_input_rep1_R1.fastq.gz RIP-Seq 2.3 GB link
— TIA1_MN_input_rep2_R1.fastq.gz RIP-Seq 2.1 GB link
— TIA1_MN_IP_rep1_R1.fastq.gz RIP-Seq 2.8 GB link
— TIA1_MN_IP_rep2_R1.fastq.gz RIP-Seq 2.3 GB link
— TIA1_Stressed_MN_input_rep1_R1.fastq.gz RIP-Seq 6.1 GB link
— TIA1_Stressed_MN_IP_rep1_R1.fastq.gz RIP-Seq 6.9 GB link
— CVB_iPSC_cyto_rep1.fastq.gz RNA-Seq 286.3 MB link
— CVB_iPSC_cyto_rep2.fastq.gz RNA-Seq 503.2 MB link
— CVB_iPSC_insol_rep1.fastq.gz RNA-Seq 528.3 MB link
— CVB_iPSC_insol_rep2.fastq.gz RNA-Seq 584.5 MB link
— CVB_iPSC_nuclei_rep1.fastq.gz RNA-Seq 393.9 MB link
— CVB_iPSC_nuclei_rep2.fastq.gz RNA-Seq 653.4 MB link
— CVB_iPSC_total_rep1.fastq.gz RNA-Seq 1.1 GB link
— CVB_iPSC_total_rep2.fastq.gz RNA-Seq 613.2 MB link
— cyto_CR463_puro_rep1.fastq.gz RNA-Seq 1.1 GB link
— cyto_CR463_puro_rep2.fastq.gz RNA-Seq 1.2 GB link
— cyto_CR463_rec_rep1.fastq.gz RNA-Seq 1.6 GB link
— cyto_CR463_rec_rep2.fastq.gz RNA-Seq 1.6 GB link
— cyto_CR463_ut_rep1.fastq.gz RNA-Seq 1.8 GB link
— cyto_CR463_ut_rep2.fastq.gz RNA-Seq 1.5 GB link
— cyto_CR464_puro_rep1.fastq.gz RNA-Seq 2.2 GB link
— cyto_CR464_puro_rep2.fastq.gz RNA-Seq 1.0 GB link
— cyto_CR464_rec_rep1.fastq.gz RNA-Seq 1.5 GB link
— cyto_CR464_rec_rep2.fastq.gz RNA-Seq 1.4 GB link
— cyto_CR464_ut_rep1.fastq.gz RNA-Seq 1.0 GB link
— cyto_CR464_ut_rep2.fastq.gz RNA-Seq 876.4 MB link
— H1_ESC_cyto_rep1.fastq.gz RNA-Seq 343.7 MB link
— H1_ESC_cyto_rep2.fastq.gz RNA-Seq 455.9 MB link
— H1_ESC_insol_rep1.fastq.gz RNA-Seq 575.7 MB link
— H1_ESC_insol_rep2.fastq.gz RNA-Seq 562.6 MB link
— H1_ESC_nuclei_rep1.fastq.gz RNA-Seq 418.8 MB link
— H1_ESC_nuclei_rep2.fastq.gz RNA-Seq 528.5 MB link
— H1_ESC_total_rep1.fastq.gz RNA-Seq 467.4 MB link
— H1_ESC_total_rep2.fastq.gz RNA-Seq 494.1 MB link
— H1_puro1_cyto_rep1.fastq.gz RNA-Seq 732.4 MB link
— H1_puro1_insol_rep1.fastq.gz RNA-Seq 1.1 GB link
— H1_puro1_nucl_rep1.fastq.gz RNA-Seq 680.8 MB link
— H1_puro1_total_rep1.fastq.gz RNA-Seq 391.1 MB link
— H1_puro_cyto_rep2.fastq.gz RNA-Seq 930.0 MB link
— H1_puro_insol_rep2.fastq.gz RNA-Seq 1.0 GB link
— H1_puro_nucl_rep2.fastq.gz RNA-Seq 828.4 MB link
— H1_puro_total_rep2.fastq.gz RNA-Seq 958.5 MB link
— H1_rec_cyto_rep1.fastq.gz RNA-Seq 774.3 MB link
— H1_rec_cyto_rep2.fastq.gz RNA-Seq 720.7 MB link
— H1_rec_insol_rep1.fastq.gz RNA-Seq 962.7 MB link
— H1_rec_insol_rep2.fastq.gz RNA-Seq 982.1 MB link
— H1_rec_nucl_rep1.fastq.gz RNA-Seq 256.8 MB link
— H1_rec_nucl_rep2.fastq.gz RNA-Seq 813.9 MB link
— H1_rec_total_rep1.fastq.gz RNA-Seq 996.3 MB link
— H1_rec_total_rep2.fastq.gz RNA-Seq 929.5 MB link
— H1_ut_cyto_rep1.fastq.gz RNA-Seq 179.0 MB link
— H1_ut_cyto_rep2.fastq.gz RNA-Seq 826.4 MB link
— H1_ut_insol_rep1.fastq.gz RNA-Seq 1.1 GB link
— H1_ut_insol_rep2.fastq.gz RNA-Seq 669.0 MB link
— H1_ut_nucl_rep1.fastq.gz RNA-Seq 773.0 MB link
— H1_ut_nucl_rep2.fastq.gz RNA-Seq 922.0 MB link
— H1_ut_total_rep1.fastq.gz RNA-Seq 1.1 GB link
— H1_ut_total_rep2.fastq.gz RNA-Seq 947.3 MB link
— H9_ESC_cyto_rep1.fastq.gz RNA-Seq 461.4 MB link
— H9_ESC_insol_rep1.fastq.gz RNA-Seq 519.9 MB link
— H9_ESC_nuclei_rep1.fastq.gz RNA-Seq 606.6 MB link
— H9_ESC_total_rep1.fastq.gz RNA-Seq 420.6 MB link
— insol_CR463_puro_rep1.fastq.gz RNA-Seq 1.2 GB link
— insol_CR463_puro_rep2.fastq.gz RNA-Seq 1.3 GB link
— insol_CR463_rec_rep1.fastq.gz RNA-Seq 1.9 GB link
— insol_CR463_rec_rep2.fastq.gz RNA-Seq 2.9 GB link
— insol_CR463_ut_rep1.fastq.gz RNA-Seq 1.7 GB link
— insol_CR463_ut_rep2.fastq.gz RNA-Seq 2.0 GB link
— insol_CR464_puro_rep1.fastq.gz RNA-Seq 1.8 GB link
— insol_CR464_puro_rep2.fastq.gz RNA-Seq 1.2 GB link
— insol_CR464_rec_rep1.fastq.gz RNA-Seq 2.5 GB link
— insol_CR464_rec_rep2.fastq.gz RNA-Seq 1.4 GB link
— insol_CR464_ut_rep1.fastq.gz RNA-Seq 1.0 GB link
— insol_CR464_ut_rep2.fastq.gz RNA-Seq 2.0 GB link
— Kin2-4_puro_cyto_rep1.fastq.gz RNA-Seq 935.0 MB link
— Kin2-4_puro_cyto_rep2.fastq.gz RNA-Seq 920.2 MB link
— Kin2-4_puro_insol_rep1.fastq.gz RNA-Seq 934.8 MB link
— Kin2-4_puro_insol_rep2.fastq.gz RNA-Seq 1004.7 MB link
— Kin2-4_puro_nucl_rep1.fastq.gz RNA-Seq 1.0 GB link
— Kin2-4_puro_nucl_rep2.fastq.gz RNA-Seq 814.0 MB link
— Kin2-4_puro_total_rep1.fastq.gz RNA-Seq 340.9 MB link
— Kin2-4_puro_total_rep2.fastq.gz RNA-Seq 1.1 GB link
— Kin2-4_ut_cyto_rep1.fastq.gz RNA-Seq 245.5 MB link
— Kin2-4_ut_cyto_rep2.fastq.gz RNA-Seq 802.8 MB link
— Kin2-4_ut_insol_rep1.fastq.gz RNA-Seq 903.1 MB link
— Kin2-4_ut_insol_rep2.fastq.gz RNA-Seq 789.8 MB link
— Kin2-4_ut_nucl_rep1.fastq.gz RNA-Seq 912.8 MB link
— Kin2-4_ut_nucl_rep2.fastq.gz RNA-Seq 1.0 GB link
— Kin2-4_ut_total_rep1.fastq.gz RNA-Seq 1.1 GB link
— Kin2-4_ut_total_rep2.fastq.gz RNA-Seq 817.9 MB link
— nuc_CR463_puro_rep1.fastq.gz RNA-Seq 951.7 MB link
— nuc_CR463_puro_rep2.fastq.gz RNA-Seq 2.5 GB link
— nuc_CR463_rec_rep1.fastq.gz RNA-Seq 645.6 MB link
— nuc_CR463_rec_rep2.fastq.gz RNA-Seq 1.1 GB link
— nuc_CR463_ut_rep1.fastq.gz RNA-Seq 1.9 GB link
— nuc_CR463_ut_rep2.fastq.gz RNA-Seq 1.2 GB link
— nuc_CR464_puro_rep1.fastq.gz RNA-Seq 2.3 GB link
— nuc_CR464_puro_rep2.fastq.gz RNA-Seq 1.1 GB link
— nuc_CR464_rec_rep1.fastq.gz RNA-Seq 1.2 GB link
— nuc_CR464_rec_rep2.fastq.gz RNA-Seq 1.3 GB link
— nuc_CR464_ut_rep1.fastq.gz RNA-Seq 1.1 GB link
— nuc_CR464_ut_rep2.fastq.gz RNA-Seq 1.4 GB link
— total_CR463_puro_rep1.fastq.gz RNA-Seq 1.9 GB link
— total_CR463_puro_rep2.fastq.gz RNA-Seq 1.1 GB link
— total_CR463_rec_rep1.fastq.gz RNA-Seq 1.2 GB link
— total_CR463_rec_rep2.fastq.gz RNA-Seq 2.2 GB link
— total_CR463_ut_rep1.fastq.gz RNA-Seq 1.9 GB link
— total_CR463_ut_rep2.fastq.gz RNA-Seq 2.0 GB link
— total_CR464_puro_rep1.fastq.gz RNA-Seq 1.1 GB link
— total_CR464_puro_rep2.fastq.gz RNA-Seq 1.2 GB link
— total_CR464_rec_rep1.fastq.gz RNA-Seq 1.5 GB link
— total_CR464_rec_rep2.fastq.gz RNA-Seq 1.3 GB link
— total_CR464_ut_rep1.fastq.gz RNA-Seq 1.9 GB link
— total_CR464_ut_rep2.fastq.gz RNA-Seq 1.7 GB link