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1 result for “astrocyte”
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Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes.
Cell reports · 2024 · 43(8): 114637
Reactive changes of glial cells during neuroinflammation impact brain disorders and disease progression. Elucidating the mechanisms that control reactive gliosis may help us to understand brain pathophysiology and improve outcomes. Here, we report that adult ablation of autism spectrum disorder …
PMID 39154337 DOI ↗
Datasets 7
Expression data from reactive astrocytes acutely purified from young adult mouse brains
Mus musculus · GPL1261
Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes [bulk RNA-seq]
Mus musculus · GPL24247
Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes [ATAC-seq]
Mus musculus · GPL24247
Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes [Microglia RNA-seq]
Mus musculus · GPL24247
Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology
Homo sapiens · GPL11154
Analyses 4
GSE271650 · 5 steps · RNA-Seq · code_examples
Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes. (2024)
GSE271651 · 8 steps · RNA-Seq · code_examples
Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes. (2024)
GSE271652 · 5 steps · ATAC-seq · code_examples
Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes. (2024)
GSE35338 · 1 step · GSE · code_examples
Genomic analysis of the molecular neuropathology of tuberous sclerosis using a human stem cell model. (2016)