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  1. The YTHDF proteins modulate Alzheimer's disease-associated brain gene signatures.

    Molecular neurodegeneration · 2026 · 21(1)

    Gene signatures of Alzheimer's disease (AD) brains reflect the output of a complex interplay of genetic, epigenetic, epi-transcriptomic, and post-transcriptional regulations. To nominate candidate factors modulating these signatures, we developed a machine learning model to integrate cellular and molecular features …

    PMID 42811341 DOI ↗

Datasets 8

GSE286096 GSE · GEO

Investigating m6A-relevant gene function in neural progenitor cells using CRISPR-Cas9 genome editing and RNA-seq

Homo sapiens · GPL24676

GSE151788 GSE · GEO

Ythdf m6A readers compensate each other in a context dependent manner [eCLIP]

GPL17021

GSE148536 GSE · GEO

Ythdf m6A readers compensate each other in a context dependent manner [Ribo-seq]

GPL21626

GSE148038 GSE · GEO

Ythdf m6A readers compensate each other in a context dependent manner [3'UTR RNA-seq]

GPL13112

GSE147849 GSE · GEO

Ythdf m6A readers compensate each other in a context dependent manner [RNA-seq]

GPL21626

GSE137258 GSE · GEO

Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer

Homo sapiens · GPL20301

GSE148039 GSE · GEO

Ythdf m6A readers compensate each other in a context dependent manner

Mus musculus · GPL13112

GSE132971 GSE · GEO

Direct RNA sequencing enables single-nucleotide m6A detection in endogenous transcript isoforms

Homo sapiens · GPL24106

Analyses 6

GSE132971 Processing Pipeline

GSE132971 · 4 steps · RNA-Seq · code_examples

Direct RNA sequencing enables m<sup>6</sup>A detection in endogenous transcript isoforms at base-specific resolution. (2020)

GSE147849 RNA-seq Data Processing

GSE147849 · 7 steps · RNA-seq · geo_data_processing

Context-dependent functional compensation between Ythdf m<sup>6</sup>A reader proteins. (2020)

GSE148038 RNA-seq Data Processing

GSE148038 · 5 steps · RNA-seq · geo_data_processing

Context-dependent functional compensation between Ythdf m<sup>6</sup>A reader proteins. (2020)

GSE148039 Processing Pipeline

GSE148039 · 7 steps · GSE · code_examples

Context-dependent functional compensation between Ythdf m<sup>6</sup>A reader proteins. (2020)

GSE148536 Ribo-seq Data Processing

GSE148536 · 7 steps · Ribo-seq · geo_data_processing

Context-dependent functional compensation between Ythdf m<sup>6</sup>A reader proteins. (2020)

GSE151788 eCLIP Data Processing

GSE151788 · 33 steps · eCLIP · geo_data_processing

Context-dependent functional compensation between Ythdf m<sup>6</sup>A reader proteins. (2020)