Non-microRNA binding competitively inhibits LIN28 regulation.
Cell reports
· 2021
· Vol. 36
(6)
· pp. 109517
Abstract
RNA binding protein (RBP) expression is finite. For RBPs that are vastly outnumbered by their potential target sites, a simple competition for binding can set the magnitude of post-transcriptional control. Here, we show that LIN28, best known for its direct regulation of let-7 miRNA biogenesis, is also indirectly regulated by its widespread binding of non-miRNA transcripts. Approximately 99% of LIN28 binding sites are found on non-miRNA transcripts, like protein coding and ribosomal RNAs. These sites are bound specifically and strongly, but they do not appear to mediate direct post-transcriptional regulation. Instead, non-miRNA sites act to sequester LIN28 protein and effectively change its functional availability, thus impeding the regulation of let-7 in cells. Together, these data show that the binding properties of the transcriptome broadly influence the ability of an RBP to mediate changes in RNA metabolism and gene expression.
Publication Types
["Journal Article", "Research Support, N.I.H., Extramural", "Research Support, U.S. Gov't, Non-P.H.S."]
MeSH Terms
["Animals", "Binding Sites", "Gene Expression Regulation", "HEK293 Cells", "Humans", "Mice", "MicroRNAs", "Mouse Embryonic Stem Cells", "Protein Binding", "RNA-Binding Proteins", "Transcriptome"]
Funding
R01 HG004659
NHGRI NIH HHS
(United States)
T32 GM008666
NIGMS NIH HHS
(United States)
U54 HG007005
NHGRI NIH HHS
(United States)
Linked Datasets (2)
A transcriptome-wide divergence in protein translation scales with LIN28B expression
Mus musculus150 data files
| File | Type | Size |
|---|---|---|
| b8p100_smallrnaseq_hek293_ko_l7_ip_S27_L002_R1_001.fastq.gz | RIP-Seq | 335.9 MB |
| b8p100_smallrnaseq_hek293_ko_l7_ip_S27_L002_R1_001.fastq.gz | RIP-Seq | 335.9 MB |
| b8p100_smallrnaseq_hek293_ko_l7_ip_S27_L002_R1_001.fastq.gz | RIP-Seq | 335.9 MB |
| b8p100_smallrnaseq_hek293_ko_l7_ip_S27_L002_R1_001.fastq.gz | RIP-Seq | 335.9 MB |
| b8p100_smallrnaseq_hek293_ko_l7_ip_S27_L002_R1_001.fastq.gz | RIP-Seq | 335.9 MB |
| b8p100_smallrnaseq_hek293_ko_l7_total_S23_L002_R1_001.fastq… | ncRNA-Seq | 457.6 MB |
| b8p100_smallrnaseq_hek293_ko_l7_total_S23_L002_R1_001.fastq… | ncRNA-Seq | 457.6 MB |
| b8p100_smallrnaseq_hek293_ko_l7_total_S23_L002_R1_001.fastq… | ncRNA-Seq | 457.6 MB |
| b8p100_smallrnaseq_hek293_ko_l7_total_S23_L002_R1_001.fastq… | ncRNA-Seq | 457.6 MB |
| b8p100_smallrnaseq_hek293_ko_l7_total_S23_L002_R1_001.fastq… | ncRNA-Seq | 457.6 MB |
| b8p100_smallrnaseq_hek293_ko_wt_ip_S25_L002_R1_001.fastq.gz | RIP-Seq | 304.6 MB |
| b8p100_smallrnaseq_hek293_ko_wt_ip_S25_L002_R1_001.fastq.gz | RIP-Seq | 304.6 MB |
| b8p100_smallrnaseq_hek293_ko_wt_ip_S25_L002_R1_001.fastq.gz | RIP-Seq | 304.6 MB |
| b8p100_smallrnaseq_hek293_ko_wt_ip_S25_L002_R1_001.fastq.gz | RIP-Seq | 304.6 MB |
| b8p100_smallrnaseq_hek293_ko_wt_ip_S25_L002_R1_001.fastq.gz | RIP-Seq | 304.6 MB |
| b8p100_smallrnaseq_hek293_ko_wt_total_S21_L002_R1_001.fastq… | ncRNA-Seq | 563.8 MB |
| b8p100_smallrnaseq_hek293_ko_wt_total_S21_L002_R1_001.fastq… | ncRNA-Seq | 563.8 MB |
| b8p100_smallrnaseq_hek293_x3_l7_ip_S28_L002_R1_001.fastq.gz | RIP-Seq | 241.0 MB |
| b8p100_smallrnaseq_hek293_x3_l7_ip_S28_L002_R1_001.fastq.gz | RIP-Seq | 241.0 MB |
| b8p100_smallrnaseq_hek293_x3_l7_ip_S28_L002_R1_001.fastq.gz | RIP-Seq | 241.0 MB |
| b8p100_smallrnaseq_hek293_x3_l7_ip_S28_L002_R1_001.fastq.gz | RIP-Seq | 241.0 MB |
| b8p100_smallrnaseq_hek293_x3_l7_ip_S28_L002_R1_001.fastq.gz | RIP-Seq | 241.0 MB |
| b8p100_smallrnaseq_hek293_x3_l7_total_S24_L002_R1_001.fastq… | ncRNA-Seq | 509.1 MB |
| b8p100_smallrnaseq_hek293_x3_l7_total_S24_L002_R1_001.fastq… | ncRNA-Seq | 509.1 MB |
| b8p100_smallrnaseq_hek293_x3_wt_ip_S26_L002_R1_001.fastq.gz | RIP-Seq | 341.6 MB |
| b8p100_smallrnaseq_hek293_x3_wt_ip_S26_L002_R1_001.fastq.gz | RIP-Seq | 341.6 MB |
| b8p100_smallrnaseq_hek293_x3_wt_ip_S26_L002_R1_001.fastq.gz | RIP-Seq | 341.6 MB |
| b8p100_smallrnaseq_hek293_x3_wt_ip_S26_L002_R1_001.fastq.gz | RIP-Seq | 341.6 MB |
| b8p100_smallrnaseq_hek293_x3_wt_ip_S26_L002_R1_001.fastq.gz | RIP-Seq | 341.6 MB |
| b8p100_smallrnaseq_hek293_x3_wt_total_S22_L002_R1_001.fastq… | ncRNA-Seq | 617.8 MB |
| b8p100_smallrnaseq_hek293_x3_wt_total_S22_L002_R1_001.fastq… | ncRNA-Seq | 617.8 MB |
| b8p37_a9_input_let7_S1_L003_R1_001.fastq.gz | RNA-Seq | 857.6 MB |
| b8p37_a9_input_let7_S1_L003_R1_001.fastq.gz | RNA-Seq | 857.6 MB |
| b8p37_a9_input_S11_L004_R1_001.fastq.gz | RNA-Seq | 912.5 MB |
| b8p37_a9_input_S11_L004_R1_001.fastq.gz | RNA-Seq | 912.5 MB |
| b8p37_a9_input_S11_L004_R1_001.fastq.gz | RNA-Seq | 912.5 MB |
| b8p37_a9_input_S11_L004_R1_001.fastq.gz | RNA-Seq | 912.5 MB |
| b8p37_a9_input_S11_L004_R1_001.fastq.gz | RNA-Seq | 912.5 MB |
| b8p37_a9_polysome_let7_S6_L003_R1_001.fastq.gz | OTHER | 274.7 MB |
| b8p37_a9_polysome_let7_S6_L003_R1_001.fastq.gz | OTHER | 274.7 MB |
| b8p37_a9_polysome_let7_S6_L003_R1_001.fastq.gz | OTHER | 274.7 MB |
| b8p37_a9_polysome_let7_S6_L003_R1_001.fastq.gz | OTHER | 274.7 MB |
| b8p37_a9_polysome_let7_S6_L003_R1_001.fastq.gz | OTHER | 274.7 MB |
| b8p37_a9_polysome_S16_L004_R1_001.fastq.gz | OTHER | 279.9 MB |
| b8p37_a9_polysome_S16_L004_R1_001.fastq.gz | OTHER | 279.9 MB |
| b8p37_a9_polysome_S16_L004_R1_001.fastq.gz | OTHER | 279.9 MB |
| b8p37_a9_polysome_S16_L004_R1_001.fastq.gz | OTHER | 279.9 MB |
| b8p37_a9_polysome_S16_L004_R1_001.fastq.gz | OTHER | 279.9 MB |
| b8p37_x1_input_S12_L004_R1_001.fastq.gz | RNA-Seq | 862.4 MB |
| b8p37_x1_input_S12_L004_R1_001.fastq.gz | RNA-Seq | 862.4 MB |
| b8p37_x1_input_S12_L004_R1_001.fastq.gz | RNA-Seq | 862.4 MB |
| b8p37_x1_input_S12_L004_R1_001.fastq.gz | RNA-Seq | 862.4 MB |
| b8p37_x1_input_S12_L004_R1_001.fastq.gz | RNA-Seq | 862.4 MB |
| b8p37_x1_polysome_S17_L004_R1_001.fastq.gz | OTHER | 284.3 MB |
| b8p37_x1_polysome_S17_L004_R1_001.fastq.gz | OTHER | 284.3 MB |
| b8p37_x1_polysome_S17_L004_R1_001.fastq.gz | OTHER | 284.3 MB |
| b8p37_x1_polysome_S17_L004_R1_001.fastq.gz | OTHER | 284.3 MB |
| b8p37_x1_polysome_S17_L004_R1_001.fastq.gz | OTHER | 284.3 MB |
| b8p37_x2_input_S13_L004_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| b8p37_x2_input_S13_L004_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| b8p37_x2_input_S13_L004_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| b8p37_x2_input_S13_L004_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| b8p37_x2_input_S13_L004_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| b8p37_x2_polysome_S18_L004_R1_001.fastq.gz | OTHER | 214.5 MB |
| b8p37_x2_polysome_S18_L004_R1_001.fastq.gz | OTHER | 214.5 MB |
| b8p37_x3_input_S14_L004_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| b8p37_x3_input_S14_L004_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| b8p37_x3_input_S14_L004_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| b8p37_x3_input_S14_L004_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| b8p37_x3_input_S14_L004_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| b8p37_x3_polysome_S19_L004_R1_001.fastq.gz | OTHER | 344.3 MB |
| b8p37_x3_polysome_S19_L004_R1_001.fastq.gz | OTHER | 344.3 MB |
| b8p37_x4_input_S15_L004_R1_001.fastq.gz | RNA-Seq | 987.2 MB |
| b8p37_x4_input_S15_L004_R1_001.fastq.gz | RNA-Seq | 987.2 MB |
| b8p37_x4_input_S15_L004_R1_001.fastq.gz | RNA-Seq | 987.2 MB |
| b8p37_x4_input_S15_L004_R1_001.fastq.gz | RNA-Seq | 987.2 MB |
| b8p37_x4_input_S15_L004_R1_001.fastq.gz | RNA-Seq | 987.2 MB |
| b8p37_x4_polysome_S20_L004_R1_001.fastq.gz | OTHER | 255.7 MB |
| b8p37_x4_polysome_S20_L004_R1_001.fastq.gz | OTHER | 255.7 MB |
| PX0_S52_L006_R1_001.fastq.gz | OTHER | 1.8 GB |
| PX0_S52_L006_R1_001.fastq.gz | OTHER | 1.8 GB |
| PX0_S52_L006_R1_001.fastq.gz | OTHER | 1.8 GB |
| PX0_S52_L006_R1_001.fastq.gz | OTHER | 1.8 GB |
| PX0_S52_L006_R1_001.fastq.gz | OTHER | 1.8 GB |
| PX1_S53_L006_R1_001.fastq.gz | OTHER | 1.5 GB |
| PX1_S53_L006_R1_001.fastq.gz | OTHER | 1.5 GB |
| PX1_S53_L006_R1_001.fastq.gz | OTHER | 1.5 GB |
| PX1_S53_L006_R1_001.fastq.gz | OTHER | 1.5 GB |
| PX1_S53_L006_R1_001.fastq.gz | OTHER | 1.5 GB |
| PX2_S54_L006_R1_001.fastq.gz | OTHER | 1.7 GB |
| PX2_S54_L006_R1_001.fastq.gz | OTHER | 1.7 GB |
| PX2_S54_L006_R1_001.fastq.gz | OTHER | 1.7 GB |
| PX2_S54_L006_R1_001.fastq.gz | OTHER | 1.7 GB |
| PX2_S54_L006_R1_001.fastq.gz | OTHER | 1.7 GB |
| PX3_S55_L006_R1_001.fastq.gz | OTHER | 1.7 GB |
| PX3_S55_L006_R1_001.fastq.gz | OTHER | 1.7 GB |
| PX3_S55_L006_R1_001.fastq.gz | OTHER | 1.7 GB |
| PX3_S55_L006_R1_001.fastq.gz | OTHER | 1.7 GB |
| PX3_S55_L006_R1_001.fastq.gz | OTHER | 1.7 GB |
| PX4_S56_L006_R1_001.fastq.gz | OTHER | 1.5 GB |
| PX4_S56_L006_R1_001.fastq.gz | OTHER | 1.5 GB |
| PX4_S56_L006_R2_001.fastq.gz | OTHER | 1.5 GB |
| PX4_S56_L006_R2_001.fastq.gz | OTHER | 1.5 GB |
| PX4_S56_L006_R2_001.fastq.gz | OTHER | 1.5 GB |
| SRR6497058 | OTHER | 214.5 MB |
| SRR6497058 | OTHER | 214.5 MB |
| SRR6497058 | OTHER | 214.5 MB |
| SRR6497059 | OTHER | 344.3 MB |
| SRR6497059 | OTHER | 344.3 MB |
| SRR6497059 | OTHER | 344.3 MB |
| SRR6497060 | OTHER | 255.7 MB |
| SRR6497060 | OTHER | 255.7 MB |
| SRR6497060 | OTHER | 255.7 MB |
| SRR6497071 | RNA-Seq | 2.0 GB |
| SRR6497071 | RNA-Seq | 2.0 GB |
| SRR6497071 | RNA-Seq | 2.0 GB |
| SRR6497074 | RNA-Seq | 1.6 GB |
| SRR6497074 | RNA-Seq | 1.6 GB |
| SRR6497074 | RNA-Seq | 1.6 GB |
| SRR6497075 | RNA-Seq | 1.8 GB |
| SRR6497075 | RNA-Seq | 1.8 GB |
| SRR6497075 | RNA-Seq | 1.8 GB |
| SRR6497079 | ncRNA-Seq | 563.8 MB |
| SRR6497079 | ncRNA-Seq | 563.8 MB |
| SRR6497079 | ncRNA-Seq | 563.8 MB |
| SRR6497081 | ncRNA-Seq | 509.1 MB |
| SRR6497081 | ncRNA-Seq | 509.1 MB |
| SRR6497081 | ncRNA-Seq | 509.1 MB |
| SRR6497083 | ncRNA-Seq | 617.8 MB |
| SRR6497083 | ncRNA-Seq | 617.8 MB |
| SRR6497083 | ncRNA-Seq | 617.8 MB |
| SRR6497085 | RNA-Seq | 857.6 MB |
| SRR6497085 | RNA-Seq | 857.6 MB |
| SRR6497085 | RNA-Seq | 857.6 MB |
| TX0_S47_L006_R1_001.fastq.gz | RNA-Seq | 2.0 GB |
| TX0_S47_L006_R1_001.fastq.gz | RNA-Seq | 2.0 GB |
| TX1_S48_L006_R1_001.fastq.gz | RNA-Seq | 1.4 GB |
| TX1_S48_L006_R1_001.fastq.gz | RNA-Seq | 1.4 GB |
| TX1_S48_L006_R1_001.fastq.gz | RNA-Seq | 1.4 GB |
| TX1_S48_L006_R1_001.fastq.gz | RNA-Seq | 1.4 GB |
| TX1_S48_L006_R1_001.fastq.gz | RNA-Seq | 1.4 GB |
| TX2_S49_L006_R1_001.fastq.gz | RNA-Seq | 1.3 GB |
| TX2_S49_L006_R1_001.fastq.gz | RNA-Seq | 1.3 GB |
| TX2_S49_L006_R1_001.fastq.gz | RNA-Seq | 1.3 GB |
| TX2_S49_L006_R1_001.fastq.gz | RNA-Seq | 1.3 GB |
| TX2_S49_L006_R1_001.fastq.gz | RNA-Seq | 1.3 GB |
| TX3_S50_L006_R1_001.fastq.gz | RNA-Seq | 1.6 GB |
| TX3_S50_L006_R1_001.fastq.gz | RNA-Seq | 1.6 GB |
| TX4_S51_L006_R1_001.fastq.gz | RNA-Seq | 1.8 GB |
| TX4_S51_L006_R1_001.fastq.gz | RNA-Seq | 1.8 GB |
Non-microRNA Binding Competitively Inhibits LIN28 Regulation
Mus musculus76 data files
| File | Type | Size |
|---|---|---|
| dd-Cit-P-1_S5_L007_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| dd-Cit-P-1_S5_L007_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| dd-Cit-P-2_S6_L007_R1_001.fastq.gz | RNA-Seq | 1.3 GB |
| dd-Cit-P-2_S6_L007_R1_001.fastq.gz | RNA-Seq | 1.3 GB |
| dd-Cit-T-1_S1_L007_R1_001.fastq.gz | RNA-Seq | 1.1 GB |
| dd-Cit-T-1_S1_L007_R1_001.fastq.gz | RNA-Seq | 1.1 GB |
| dd-Cit-T-2_S2_L007_R1_001.fastq.gz | RNA-Seq | 1.4 GB |
| dd-Cit-T-2_S2_L007_R1_001.fastq.gz | RNA-Seq | 1.4 GB |
| dd-HpK-P-1_S7_L007_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| dd-HpK-P-1_S7_L007_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| dd-HpK-P-2_S8_L007_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| dd-HpK-P-2_S8_L007_R1_001.fastq.gz | RNA-Seq | 1.2 GB |
| dd-HpK-T-1_S3_L007_R1_001.fastq.gz | RNA-Seq | 1.5 GB |
| dd-HpK-T-1_S3_L007_R1_001.fastq.gz | RNA-Seq | 1.5 GB |
| dd-HpK-T-2_S4_L007_R1_001.fastq.gz | RNA-Seq | 1.6 GB |
| dd-HpK-T-2_S4_L007_R1_001.fastq.gz | RNA-Seq | 1.6 GB |
| HPK_mESCs_IN7_mock_R1_merged.fastq.gz | RNA-Seq | 1.2 GB |
| HPK_mESCs_IN7_mock_R1_merged.fastq.gz | RNA-Seq | 1.2 GB |
| HPK_mESCs_IP3_mock_S20_L007_R1_001.fastq.gz | RNA-Seq | 1.4 GB |
| HPK_mESCs_IP3_mock_S20_L007_R1_001.fastq.gz | RNA-Seq | 1.4 GB |
| HPK_mESCs_IP7_mock_R1_merged.fastq.gz | RNA-Seq | 1.2 GB |
| HPK_mESCs_IP7_mock_R1_merged.fastq.gz | RNA-Seq | 1.2 GB |
| Hpk_mock_1_poly_S7_L001_R1_001.fastq.gz | RNA-Seq | 793.0 MB |
| Hpk_mock_1_poly_S7_L001_R1_001.fastq.gz | RNA-Seq | 793.0 MB |
| Hpk_mock_1_S5_L001_R1_001.fastq.gz | RNA-Seq | 927.7 MB |
| Hpk_mock_1_S5_L001_R1_001.fastq.gz | RNA-Seq | 927.7 MB |
| Hpk_mock_2_poly_S19_L002_R1_001.fastq.gz | RNA-Seq | 842.0 MB |
| Hpk_mock_2_poly_S19_L002_R1_001.fastq.gz | RNA-Seq | 842.0 MB |
| Hpk_mock_2_S17_L002_R1_001.fastq.gz | RNA-Seq | 874.2 MB |
| Hpk_mock_2_S17_L002_R1_001.fastq.gz | RNA-Seq | 874.2 MB |
| LIN28B_PHI_1_CLIP_R1_S32_L002_R1_A01_B06.fastq.gz | RNA-Seq | 460.8 MB |
| LIN28B_PHI_1_CLIP_R1_S32_L002_R1_A01_B06.fastq.gz | RNA-Seq | 460.8 MB |
| LIN28B_PHI_1_CLIP_R2_S24_L002_R1_A01_B06.fastq.gz | RNA-Seq | 305.6 MB |
| LIN28B_PHI_1_CLIP_R2_S24_L002_R1_A01_B06.fastq.gz | RNA-Seq | 305.6 MB |
| LIN28B_PHI_1_INPUT_R1_S29_L002_R1.fastq.gz | RNA-Seq | 1.2 GB |
| LIN28B_PHI_1_INPUT_R1_S29_L002_R1.fastq.gz | RNA-Seq | 1.2 GB |
| LIN28B_PHI_1_INPUT_R2_S21_L002_R1.fastq.gz | RNA-Seq | 786.1 MB |
| LIN28B_PHI_1_INPUT_R2_S21_L002_R1.fastq.gz | RNA-Seq | 786.1 MB |
| LIN28B_PHI_2_CLIP_R1_S31_L002_R1_C01_D08.fastq.gz | RNA-Seq | 420.8 MB |
| LIN28B_PHI_2_CLIP_R1_S31_L002_R1_C01_D08.fastq.gz | RNA-Seq | 420.8 MB |
| LIN28B_PHI_2_CLIP_R2_S23_L002_R1_C01_D08.fastq.gz | RNA-Seq | 361.7 MB |
| LIN28B_PHI_2_CLIP_R2_S23_L002_R1_C01_D08.fastq.gz | RNA-Seq | 361.7 MB |
| LIN28B_PHI_2_INPUT_R1_S30_L002_R1.fastq.gz | RNA-Seq | 1.1 GB |
| LIN28B_PHI_2_INPUT_R1_S30_L002_R1.fastq.gz | RNA-Seq | 1.1 GB |
| LIN28B_PHI_2_INPUT_R2_S22_L002_R1.fastq.gz | RNA-Seq | 1009.7 MB |
| LIN28B_PHI_2_INPUT_R2_S22_L002_R1.fastq.gz | RNA-Seq | 1009.7 MB |
| LIN28B_PHI_3_CLIP_R1_S28_L002_R1_A04_F05.fastq.gz | RNA-Seq | 439.3 MB |
| LIN28B_PHI_3_CLIP_R1_S28_L002_R1_A04_F05.fastq.gz | RNA-Seq | 439.3 MB |
| LIN28B_PHI_3_CLIP_R2_S20_L002_R1_A04_F05.fastq.gz | RNA-Seq | 425.0 MB |
| LIN28B_PHI_3_CLIP_R2_S20_L002_R1_A04_F05.fastq.gz | RNA-Seq | 425.0 MB |
| LIN28B_PHI_3_INPUT_R1_S25_L002_R1.fastq.gz | RNA-Seq | 715.9 MB |
| LIN28B_PHI_3_INPUT_R1_S25_L002_R1.fastq.gz | RNA-Seq | 715.9 MB |
| LIN28B_PHI_3_INPUT_R2_S17_L002_R1.fastq.gz | RNA-Seq | 1.0 GB |
| LIN28B_PHI_3_INPUT_R2_S17_L002_R1.fastq.gz | RNA-Seq | 1.0 GB |
| LIN28B_PHI_4_CLIP_R1_S27_L002_R1_X2A_X2B.fastq.gz | RNA-Seq | 445.6 MB |
| LIN28B_PHI_4_CLIP_R1_S27_L002_R1_X2A_X2B.fastq.gz | RNA-Seq | 445.6 MB |
| LIN28B_PHI_4_CLIP_R2_S19_L002_R1_X2A_X2B.fastq.gz | RNA-Seq | 783.6 MB |
| LIN28B_PHI_4_CLIP_R2_S19_L002_R1_X2A_X2B.fastq.gz | RNA-Seq | 783.6 MB |
| LIN28B_PHI_4_INPUT_R1_S26_L002_R1.fastq.gz | RNA-Seq | 1.1 GB |
| LIN28B_PHI_4_INPUT_R1_S26_L002_R1.fastq.gz | RNA-Seq | 1.1 GB |
| LIN28B_PHI_4_INPUT_R2_S18_L002_R1.fastq.gz | RNA-Seq | 958.2 MB |
| LIN28B_PHI_4_INPUT_R2_S18_L002_R1.fastq.gz | RNA-Seq | 958.2 MB |
| V6_5_mESCs_IN1_mock_R1_merged.fastq.gz | RNA-Seq | 1.1 GB |
| V6_5_mESCs_IN1_mock_R1_merged.fastq.gz | RNA-Seq | 1.1 GB |
| V6_5_mESCs_IP1_mock_S19_L007_R1_001.fastq.gz | RNA-Seq | 1.1 GB |
| V6_5_mESCs_IP1_mock_S19_L007_R1_001.fastq.gz | RNA-Seq | 1.1 GB |
| V6_5_mESCs_IP5_mock_S21_L007_R1_001.fastq.gz | RNA-Seq | 1.4 GB |
| V6_5_mESCs_IP5_mock_S21_L007_R1_001.fastq.gz | RNA-Seq | 1.4 GB |
| V6_5_mock_1_poly_S3_L001_R1_001.fastq.gz | RNA-Seq | 785.1 MB |
| V6_5_mock_1_poly_S3_L001_R1_001.fastq.gz | RNA-Seq | 785.1 MB |
| V6_5_mock_1_S1_L001_R1_001.fastq.gz | RNA-Seq | 860.6 MB |
| V6_5_mock_1_S1_L001_R1_001.fastq.gz | RNA-Seq | 860.6 MB |
| V6_5_mock_2_poly_S15_L002_R1_001.fastq.gz | RNA-Seq | 910.9 MB |
| V6_5_mock_2_poly_S15_L002_R1_001.fastq.gz | RNA-Seq | 910.9 MB |
| V6_5_mock_2_S13_L002_R1_001.fastq.gz | RNA-Seq | 874.1 MB |
| V6_5_mock_2_S13_L002_R1_001.fastq.gz | RNA-Seq | 874.1 MB |
Analysis Pipelines (1)
GSE178259 eCLIP Data Processing
6 steps