Short 5' UTRs serve as a marker for viral mRNA translation inhibition by the IFIT2-IFIT3 antiviral complex.
Dustin R Glasner,
Candace Todd,
Brian Cook,
Agustina D'Urso,
Shivani Khosla,
Elena Estrada,
Jaxon D Wagner,
Mason D Bartels,
Pierce Ford,
Jordan Prych,
Katie Hatch,
Brian A Yee,
Kaori M Ego,
Qishan Liang,
Sarah R Holland,
James Brett Case,
Kevin D Corbett,
Michael S Diamond,
Gene W Yeo,
Mark A Herzik,
Eric L Van Nostrand,
Matthew D Daugherty
bioRxiv : the preprint server for biology
· 2025
Abstract
Recognition of "non-self" nucleic acids, including cytoplasmic dsDNA, dsRNA, or mRNAs lacking proper 5' cap structures, is critical for the innate immune response to viruses. Here, we demonstrate that short 5' untranslated regions (UTRs), a characteristic of many viral mRNAs, can also serve as a molecular pattern for innate immune recognition via the interferon-induced proteins IFIT2 and IFIT3. The IFIT2-IFIT3 heterodimer, formed through an intricate domain swap structure resolved by cryo-EM, mediates viral mRNA 5' end recognition, translation inhibition, and ultimately antiviral activity. Critically, 5' UTR lengths <50 nucleotides are necessary and sufficient to sensitize an mRNA to translation inhibition by the IFIT2-IFIT3 complex. Accordingly, diverse viruses whose mRNAs contain short 5' UTRs, such as vesicular stomatitis virus and parainfluenza virus 3, are sensitive to IFIT2-IFIT3-mediated antiviral activity. Our work thus reveals a pattern of antiviral nucleic acid immune recognition that takes advantage of the inherent constraints on viral genome size.
Publication Types
["Journal Article", "Preprint"]
MeSH Terms
[]
Funding
U24 HG009889
NHGRI NIH HHS
(United States)
R01 HG004659
NHGRI NIH HHS
(United States)
U24 HG011735
NHGRI NIH HHS
(United States)
RF1 MH126719
NIMH NIH HHS
(United States)
R01 HG011864
NHGRI NIH HHS
(United States)
R35 GM144121
NIGMS NIH HHS
(United States)
R35 GM133633
NIGMS NIH HHS
(United States)
R00 HG009530
NHGRI NIH HHS
(United States)
K22 AI119017
NIAID NIH HHS
(United States)
T32 GM133351
NIGMS NIH HHS
(United States)
Linked Datasets (1)
Short 5â UTRs serve as a marker for mRNA translation inhibition by the IFIT2-IFIT3 antiviral complex
Mus musculus261 data files
| File | Type | Size |
|---|---|---|
| E_FLAG_INPUT_1_S72_L005_R1_001.fastq.gz | OTHER | 490.4 MB |
| E_FLAG_INPUT_1_S72_L005_R1_001.fastq.gz | OTHER | 490.4 MB |
| E_FLAG_INPUT_1_S72_L005_R1_001.fastq.gz | OTHER | 490.4 MB |
| E_FLAG_INPUT_2_S91_L006_R1_001.fastq.gz | OTHER | 443.8 MB |
| E_FLAG_INPUT_2_S91_L006_R1_001.fastq.gz | OTHER | 443.8 MB |
| E_FLAG_INPUT_2_S91_L006_R1_001.fastq.gz | OTHER | 443.8 MB |
| E_FLAG_INPUT_3_S121_L007_R1_001.fastq.gz | OTHER | 572.7 MB |
| E_FLAG_INPUT_3_S121_L007_R1_001.fastq.gz | OTHER | 572.7 MB |
| E_FLAG_INPUT_3_S121_L007_R1_001.fastq.gz | OTHER | 572.7 MB |
| E_FLAG_IP_1_S65_L005_R1_001.fastq.gz | OTHER | 531.1 MB |
| E_FLAG_IP_1_S65_L005_R1_001.fastq.gz | OTHER | 531.1 MB |
| E_FLAG_IP_1_S65_L005_R1_001.fastq.gz | OTHER | 531.1 MB |
| E_FLAG_IP_2_S85_L006_R1_001.fastq.gz | OTHER | 484.0 MB |
| E_FLAG_IP_2_S85_L006_R1_001.fastq.gz | OTHER | 484.0 MB |
| E_FLAG_IP_2_S85_L006_R1_001.fastq.gz | OTHER | 484.0 MB |
| E_FLAG_IP_3_S114_L007_R1_001.fastq.gz | OTHER | 693.8 MB |
| E_FLAG_IP_3_S114_L007_R1_001.fastq.gz | OTHER | 693.8 MB |
| E_FLAG_IP_3_S114_L007_R1_001.fastq.gz | OTHER | 693.8 MB |
| E_HA_INPUT_1_S71_L005_R1_001.fastq.gz | OTHER | 437.4 MB |
| E_HA_INPUT_1_S71_L005_R1_001.fastq.gz | OTHER | 437.4 MB |
| E_HA_INPUT_1_S71_L005_R1_001.fastq.gz | OTHER | 437.4 MB |
| E_HA_INPUT_2_S90_L006_R1_001.fastq.gz | OTHER | 322.0 MB |
| E_HA_INPUT_2_S90_L006_R1_001.fastq.gz | OTHER | 322.0 MB |
| E_HA_INPUT_2_S90_L006_R1_001.fastq.gz | OTHER | 322.0 MB |
| E_HA_INPUT_3_S120_L007_R1_001.fastq.gz | OTHER | 398.6 MB |
| E_HA_INPUT_3_S120_L007_R1_001.fastq.gz | OTHER | 398.6 MB |
| E_HA_INPUT_3_S120_L007_R1_001.fastq.gz | OTHER | 398.6 MB |
| E_HA_IP_1_S64_L005_R1_001.fastq.gz | OTHER | 445.4 MB |
| E_HA_IP_1_S64_L005_R1_001.fastq.gz | OTHER | 445.4 MB |
| E_HA_IP_1_S64_L005_R1_001.fastq.gz | OTHER | 445.4 MB |
| E_HA_IP_2_S84_L006_R1_001.fastq.gz | OTHER | 354.3 MB |
| E_HA_IP_2_S84_L006_R1_001.fastq.gz | OTHER | 354.3 MB |
| E_HA_IP_2_S84_L006_R1_001.fastq.gz | OTHER | 354.3 MB |
| E_HA_IP_3_S113_L007_R1_001.fastq.gz | OTHER | 774.3 MB |
| E_HA_IP_3_S113_L007_R1_001.fastq.gz | OTHER | 774.3 MB |
| E_HA_IP_3_S113_L007_R1_001.fastq.gz | OTHER | 774.3 MB |
| H1_INPUT_1_S73_L005_R1_001.fastq.gz | OTHER | 430.1 MB |
| H1_INPUT_1_S73_L005_R1_001.fastq.gz | OTHER | 430.1 MB |
| H1_INPUT_1_S73_L005_R1_001.fastq.gz | OTHER | 430.1 MB |
| H1_INPUT_2_S92_L006_R1_001.fastq.gz | OTHER | 372.4 MB |
| H1_INPUT_2_S92_L006_R1_001.fastq.gz | OTHER | 372.4 MB |
| H1_INPUT_2_S92_L006_R1_001.fastq.gz | OTHER | 372.4 MB |
| H1_INPUT_3_S122_L007_R1_001.fastq.gz | OTHER | 440.0 MB |
| H1_INPUT_3_S122_L007_R1_001.fastq.gz | OTHER | 440.0 MB |
| H1_INPUT_3_S122_L007_R1_001.fastq.gz | OTHER | 440.0 MB |
| H1_IP_1_S66_L005_R1_001.fastq.gz | OTHER | 555.0 MB |
| H1_IP_1_S66_L005_R1_001.fastq.gz | OTHER | 555.0 MB |
| H1_IP_1_S66_L005_R1_001.fastq.gz | OTHER | 555.0 MB |
| H1_IP_1_S66_L006_R1_001.fastq.gz | OTHER | 409.6 MB |
| H1_IP_1_S66_L006_R1_001.fastq.gz | OTHER | 409.6 MB |
| H1_IP_1_S66_L006_R1_001.fastq.gz | OTHER | 409.6 MB |
| H1_IP_3_S115_L007_R1_001.fastq.gz | OTHER | 654.3 MB |
| H1_IP_3_S115_L007_R1_001.fastq.gz | OTHER | 654.3 MB |
| H1_IP_3_S115_L007_R1_001.fastq.gz | OTHER | 654.3 MB |
| INPUT-2KO-INF-A_R1_001.fastq.gz | OTHER | 451.2 MB |
| INPUT-2KO-INF-A_R1_001.fastq.gz | OTHER | 451.2 MB |
| INPUT-2KO-INF-A_R1_001.fastq.gz | OTHER | 451.2 MB |
| INPUT-2KO-INF-B_R1_001.fastq.gz | OTHER | 424.4 MB |
| INPUT-2KO-INF-B_R1_001.fastq.gz | OTHER | 424.4 MB |
| INPUT-2KO-INF-B_R1_001.fastq.gz | OTHER | 424.4 MB |
| INPUT-2KO-VSV-INF-A_R1_001.fastq.gz | OTHER | 446.2 MB |
| INPUT-2KO-VSV-INF-A_R1_001.fastq.gz | OTHER | 446.2 MB |
| INPUT-2KO-VSV-INF-A_R1_001.fastq.gz | OTHER | 446.2 MB |
| INPUT-2KO-VSV-INF-B_R1_001.fastq.gz | OTHER | 456.7 MB |
| INPUT-2KO-VSV-INF-B_R1_001.fastq.gz | OTHER | 456.7 MB |
| INPUT-2KO-VSV-INF-B_R1_001.fastq.gz | OTHER | 456.7 MB |
| INPUT-3KO-INF-A_R1_001.fastq.gz | OTHER | 389.2 MB |
| INPUT-3KO-INF-A_R1_001.fastq.gz | OTHER | 389.2 MB |
| INPUT-3KO-INF-A_R1_001.fastq.gz | OTHER | 389.2 MB |
| INPUT-3KO-VSV-INF-A_R1_001.fastq.gz | OTHER | 347.1 MB |
| INPUT-3KO-VSV-INF-A_R1_001.fastq.gz | OTHER | 347.1 MB |
| INPUT-3KO-VSV-INF-A_R1_001.fastq.gz | OTHER | 347.1 MB |
| INPUT-3KO-VSV-INF-B_R1_001.fastq.gz | OTHER | 337.2 MB |
| INPUT-3KO-VSV-INF-B_R1_001.fastq.gz | OTHER | 337.2 MB |
| INPUT-3KO-VSV-INF-B_R1_001.fastq.gz | OTHER | 337.2 MB |
| INPUT-WT-INF-A_R1_001.fastq.gz | OTHER | 363.0 MB |
| INPUT-WT-INF-A_R1_001.fastq.gz | OTHER | 363.0 MB |
| INPUT-WT-INF-A_R1_001.fastq.gz | OTHER | 363.0 MB |
| INPUT-WT-INF-B_R1_001.fastq.gz | OTHER | 390.4 MB |
| INPUT-WT-INF-B_R1_001.fastq.gz | OTHER | 390.4 MB |
| INPUT-WT-INF-B_R1_001.fastq.gz | OTHER | 390.4 MB |
| INPUT-WT-NO-INF-A_R1_001.fastq.gz | OTHER | 371.9 MB |
| INPUT-WT-NO-INF-A_R1_001.fastq.gz | OTHER | 371.9 MB |
| INPUT-WT-NO-INF-A_R1_001.fastq.gz | OTHER | 371.9 MB |
| INPUT-WT-NO-INF-B_R1_001.fastq.gz | OTHER | 407.0 MB |
| INPUT-WT-NO-INF-B_R1_001.fastq.gz | OTHER | 407.0 MB |
| INPUT-WT-NO-INF-B_R1_001.fastq.gz | OTHER | 407.0 MB |
| INPUT-WT-VSV-A_R1_001.fastq.gz | OTHER | 356.5 MB |
| INPUT-WT-VSV-A_R1_001.fastq.gz | OTHER | 356.5 MB |
| INPUT-WT-VSV-A_R1_001.fastq.gz | OTHER | 356.5 MB |
| INPUT-WT-VSV-B_R1_001.fastq.gz | OTHER | 317.9 MB |
| INPUT-WT-VSV-B_R1_001.fastq.gz | OTHER | 317.9 MB |
| INPUT-WT-VSV-B_R1_001.fastq.gz | OTHER | 317.9 MB |
| INPUT-WT-VSV-INF-A_R1_001.fastq.gz | OTHER | 321.2 MB |
| INPUT-WT-VSV-INF-A_R1_001.fastq.gz | OTHER | 321.2 MB |
| INPUT-WT-VSV-INF-A_R1_001.fastq.gz | OTHER | 321.2 MB |
| INPUT-WT-VSV-INF-B_R1_001.fastq.gz | OTHER | 301.6 MB |
| IP-2KO-INF-2A_R1_001.fastq.gz | OTHER | 386.1 MB |
| IP-2KO-INF-2A_R1_001.fastq.gz | OTHER | 386.1 MB |
| IP-2KO-INF-2A_R1_001.fastq.gz | OTHER | 386.1 MB |
| IP-2KO-INF-2B_R1_001.fastq.gz | OTHER | 378.3 MB |
| IP-2KO-INF-2B_R1_001.fastq.gz | OTHER | 378.3 MB |
| IP-2KO-INF-2B_R1_001.fastq.gz | OTHER | 378.3 MB |
| IP-2KO-INF-3A_R1_001.fastq.gz | OTHER | 448.2 MB |
| IP-2KO-INF-3A_R1_001.fastq.gz | OTHER | 448.2 MB |
| IP-2KO-INF-3A_R1_001.fastq.gz | OTHER | 448.2 MB |
| IP-2KO-INF-3B_R1_001.fastq.gz | OTHER | 412.1 MB |
| IP-2KO-INF-3B_R1_001.fastq.gz | OTHER | 412.1 MB |
| IP-2KO-INF-3B_R1_001.fastq.gz | OTHER | 412.1 MB |
| IP-2KO-VSV-INF-2A_R1_001.fastq.gz | OTHER | 383.9 MB |
| IP-2KO-VSV-INF-2A_R1_001.fastq.gz | OTHER | 383.9 MB |
| IP-2KO-VSV-INF-2A_R1_001.fastq.gz | OTHER | 383.9 MB |
| IP-2KO-VSV-INF-2-B_R1_001.fastq.gz | OTHER | 370.0 MB |
| IP-2KO-VSV-INF-2-B_R1_001.fastq.gz | OTHER | 370.0 MB |
| IP-2KO-VSV-INF-2-B_R1_001.fastq.gz | OTHER | 370.0 MB |
| IP-2KO-VSV-INF-3A_R1_001.fastq.gz | OTHER | 351.8 MB |
| IP-2KO-VSV-INF-3A_R1_001.fastq.gz | OTHER | 351.8 MB |
| IP-2KO-VSV-INF-3A_R1_001.fastq.gz | OTHER | 351.8 MB |
| IP-2KO-VSV-INF-3-B_R1_001.fastq.gz | OTHER | 373.3 MB |
| IP-2KO-VSV-INF-3-B_R1_001.fastq.gz | OTHER | 373.3 MB |
| IP-2KO-VSV-INF-3-B_R1_001.fastq.gz | OTHER | 373.3 MB |
| IP-3KO-INF-2-A_R1_001.fastq.gz | OTHER | 422.1 MB |
| IP-3KO-INF-2-A_R1_001.fastq.gz | OTHER | 422.1 MB |
| IP-3KO-INF-2-A_R1_001.fastq.gz | OTHER | 422.1 MB |
| IP-3KO-INF-3-A_R1_001.fastq.gz | OTHER | 493.6 MB |
| IP-3KO-INF-3-B_R1_001.fastq.gz | OTHER | 451.7 MB |
| IP-3KO-INF-3-B_R1_001.fastq.gz | OTHER | 451.7 MB |
| IP-3KO-INF-3-B_R1_001.fastq.gz | OTHER | 451.7 MB |
| IP-3KO-VSV-INF-2-A_R1_001.fastq.gz | OTHER | 434.3 MB |
| IP-3KO-VSV-INF-2-A_R1_001.fastq.gz | OTHER | 434.3 MB |
| IP-3KO-VSV-INF-2-A_R1_001.fastq.gz | OTHER | 434.3 MB |
| IP-3KO-VSV-INF-2-B_R1_001.fastq.gz | OTHER | 461.7 MB |
| IP-3KO-VSV-INF-2-B_R1_001.fastq.gz | OTHER | 461.7 MB |
| IP-3KO-VSV-INF-2-B_R1_001.fastq.gz | OTHER | 461.7 MB |
| IP-3KO-VSV-INF-3-A_R1_001.fastq.gz | OTHER | 438.0 MB |
| IP-3KO-VSV-INF-3-A_R1_001.fastq.gz | OTHER | 438.0 MB |
| IP-3KO-VSV-INF-3-A_R1_001.fastq.gz | OTHER | 438.0 MB |
| IP-WT-INF-2-A_R1_001.fastq.gz | OTHER | 411.1 MB |
| IP-WT-INF-2-A_R1_001.fastq.gz | OTHER | 411.1 MB |
| IP-WT-INF-2-A_R1_001.fastq.gz | OTHER | 411.1 MB |
| IP-WT-INF-2-B_R1_001.fastq.gz | OTHER | 431.1 MB |
| IP-WT-INF-2-B_R1_001.fastq.gz | OTHER | 431.1 MB |
| IP-WT-INF-2-B_R1_001.fastq.gz | OTHER | 431.1 MB |
| IP-WT-INF-3-A_R1_001.fastq.gz | OTHER | 467.9 MB |
| IP-WT-INF-3-A_R1_001.fastq.gz | OTHER | 467.9 MB |
| IP-WT-INF-3-A_R1_001.fastq.gz | OTHER | 467.9 MB |
| IP-WT-INF-3-B_R1_001.fastq.gz | OTHER | 357.5 MB |
| IP-WT-NO-INF-2-A_R1_001.fastq.gz | OTHER | 383.1 MB |
| IP-WT-NO-INF-2-A_R1_001.fastq.gz | OTHER | 383.1 MB |
| IP-WT-NO-INF-2-A_R1_001.fastq.gz | OTHER | 383.1 MB |
| IP-WT-NO-INF-2-B_R1_001.fastq.gz | OTHER | 411.8 MB |
| IP-WT-NO-INF-2-B_R1_001.fastq.gz | OTHER | 411.8 MB |
| IP-WT-NO-INF-2-B_R1_001.fastq.gz | OTHER | 411.8 MB |
| IP-WT-NO-INF-3-A_R1_001.fastq.gz | OTHER | 387.8 MB |
| IP-WT-NO-INF-3-A_R1_001.fastq.gz | OTHER | 387.8 MB |
| IP-WT-NO-INF-3-A_R1_001.fastq.gz | OTHER | 387.8 MB |
| IP-WT-NO-INF-3-B_R1_001.fastq.gz | OTHER | 352.0 MB |
| IP-WT-NO-INF-3-B_R1_001.fastq.gz | OTHER | 352.0 MB |
| IP-WT-NO-INF-3-B_R1_001.fastq.gz | OTHER | 352.0 MB |
| IP-WT-VSV-2-A_R1_001.fastq.gz | OTHER | 461.6 MB |
| IP-WT-VSV-2-A_R1_001.fastq.gz | OTHER | 461.6 MB |
| IP-WT-VSV-2-A_R1_001.fastq.gz | OTHER | 461.6 MB |
| IP-WT-VSV-2-B_R1_001.fastq.gz | OTHER | 389.3 MB |
| IP-WT-VSV-2-B_R1_001.fastq.gz | OTHER | 389.3 MB |
| IP-WT-VSV-2-B_R1_001.fastq.gz | OTHER | 389.3 MB |
| IP-WT-VSV-3-A_R1_001.fastq.gz | OTHER | 360.4 MB |
| IP-WT-VSV-3-A_R1_001.fastq.gz | OTHER | 360.4 MB |
| IP-WT-VSV-3-A_R1_001.fastq.gz | OTHER | 360.4 MB |
| IP-WT-VSV-3-B_R1_001.fastq.gz | OTHER | 310.4 MB |
| IP-WT-VSV-3-B_R1_001.fastq.gz | OTHER | 310.4 MB |
| IP-WT-VSV-3-B_R1_001.fastq.gz | OTHER | 310.4 MB |
| IP-WT-VSV-INF-2-A_R1_001.fastq.gz | OTHER | 364.8 MB |
| IP-WT-VSV-INF-2-A_R1_001.fastq.gz | OTHER | 364.8 MB |
| IP-WT-VSV-INF-2-A_R1_001.fastq.gz | OTHER | 364.8 MB |
| IP-WT-VSV-INF-2-B_R1_001.fastq.gz | OTHER | 397.2 MB |
| IP-WT-VSV-INF-3-A_R1_001.fastq.gz | OTHER | 400.5 MB |
| IP-WT-VSV-INF-3-A_R1_001.fastq.gz | OTHER | 400.5 MB |
| IP-WT-VSV-INF-3-A_R1_001.fastq.gz | OTHER | 400.5 MB |
| IP-WT-VSV-INF-3B_R1_001.fastq.gz | OTHER | 359.0 MB |
| IP-WT-VSV-INF-3B_R1_001.fastq.gz | OTHER | 359.0 MB |
| IP-WT-VSV-INF-3B_R1_001.fastq.gz | OTHER | 359.0 MB |
| M23_FLAG_INPUT_1_S77_L005_R1_001.fastq.gz | OTHER | 378.5 MB |
| M23_FLAG_INPUT_1_S77_L005_R1_001.fastq.gz | OTHER | 378.5 MB |
| M23_FLAG_INPUT_1_S77_L005_R1_001.fastq.gz | OTHER | 378.5 MB |
| M23_FLAG_INPUT_2_S96_L006_R1_001.fastq.gz | OTHER | 485.1 MB |
| M23_FLAG_INPUT_2_S96_L006_R1_001.fastq.gz | OTHER | 485.1 MB |
| M23_FLAG_INPUT_2_S96_L006_R1_001.fastq.gz | OTHER | 485.1 MB |
| M23_FLAG_INPUT_3_S126_L007_R1_001.fastq.gz | OTHER | 475.9 MB |
| M23_FLAG_INPUT_3_S126_L007_R1_001.fastq.gz | OTHER | 475.9 MB |
| M23_FLAG_INPUT_3_S126_L007_R1_001.fastq.gz | OTHER | 475.9 MB |
| M23_FLAG_IP_1_S70_L005_R1_001.fastq.gz | OTHER | 1.4 GB |
| M23_FLAG_IP_1_S70_L005_R1_001.fastq.gz | OTHER | 1.4 GB |
| M23_FLAG_IP_1_S70_L005_R1_001.fastq.gz | OTHER | 1.4 GB |
| M23_FLAG_IP_2_S89_L006_R1_001.fastq.gz | OTHER | 1.1 GB |
| M23_FLAG_IP_2_S89_L006_R1_001.fastq.gz | OTHER | 1.1 GB |
| M23_FLAG_IP_2_S89_L006_R1_001.fastq.gz | OTHER | 1.1 GB |
| M23_FLAG_IP_3_S119_L007_R1_001.fastq.gz | OTHER | 624.9 MB |
| M23_FLAG_IP_3_S119_L007_R1_001.fastq.gz | OTHER | 624.9 MB |
| M23_FLAG_IP_3_S119_L007_R1_001.fastq.gz | OTHER | 624.9 MB |
| M23_HA_INPUT_1_S76_L005_R1_001.fastq.gz | OTHER | 458.4 MB |
| M23_HA_INPUT_1_S76_L005_R1_001.fastq.gz | OTHER | 458.4 MB |
| M23_HA_INPUT_1_S76_L005_R1_001.fastq.gz | OTHER | 458.4 MB |
| M23_HA_INPUT_2_S95_L006_R1_001.fastq.gz | OTHER | 437.1 MB |
| M23_HA_INPUT_2_S95_L006_R1_001.fastq.gz | OTHER | 437.1 MB |
| M23_HA_INPUT_2_S95_L006_R1_001.fastq.gz | OTHER | 437.1 MB |
| M23_HA_INPUT_3_S125_L007_R1_001.fastq.gz | OTHER | 408.4 MB |
| M23_HA_INPUT_3_S125_L007_R1_001.fastq.gz | OTHER | 408.4 MB |
| M23_HA_INPUT_3_S125_L007_R1_001.fastq.gz | OTHER | 408.4 MB |
| M23_HA_IP_1_S69_L005_R1_001.fastq.gz | OTHER | 1.1 GB |
| M23_HA_IP_1_S69_L005_R1_001.fastq.gz | OTHER | 1.1 GB |
| M23_HA_IP_1_S69_L005_R1_001.fastq.gz | OTHER | 1.1 GB |
| M23_HA_IP_2_S88_L006_R1_001.fastq.gz | OTHER | 1.2 GB |
| M23_HA_IP_2_S88_L006_R1_001.fastq.gz | OTHER | 1.2 GB |
| M23_HA_IP_2_S88_L006_R1_001.fastq.gz | OTHER | 1.2 GB |
| M23_HA_IP_3_S118_L007_R1_001.fastq.gz | OTHER | 646.4 MB |
| M23_HA_IP_3_S118_L007_R1_001.fastq.gz | OTHER | 646.4 MB |
| M23_HA_IP_3_S118_L007_R1_001.fastq.gz | OTHER | 646.4 MB |
| M2_INPUT_1_S74_L005_R1_001.fastq.gz | OTHER | 460.5 MB |
| M2_INPUT_1_S74_L005_R1_001.fastq.gz | OTHER | 460.5 MB |
| M2_INPUT_1_S74_L005_R1_001.fastq.gz | OTHER | 460.5 MB |
| M2_INPUT_2_S93_L006_R1_001.fastq.gz | OTHER | 532.5 MB |
| M2_INPUT_2_S93_L006_R1_001.fastq.gz | OTHER | 532.5 MB |
| M2_INPUT_2_S93_L006_R1_001.fastq.gz | OTHER | 532.5 MB |
| M2_INPUT_3_S123_L007_R1_001.fastq.gz | OTHER | 504.0 MB |
| M2_INPUT_3_S123_L007_R1_001.fastq.gz | OTHER | 504.0 MB |
| M2_INPUT_3_S123_L007_R1_001.fastq.gz | OTHER | 504.0 MB |
| M2_IP_1_S67_L005_R1_001.fastq.gz | OTHER | 535.2 MB |
| M2_IP_1_S67_L005_R1_001.fastq.gz | OTHER | 535.2 MB |
| M2_IP_1_S67_L005_R1_001.fastq.gz | OTHER | 535.2 MB |
| M2_IP_2_S86_L006_R1_001.fastq.gz | OTHER | 447.2 MB |
| M2_IP_2_S86_L006_R1_001.fastq.gz | OTHER | 447.2 MB |
| M2_IP_2_S86_L006_R1_001.fastq.gz | OTHER | 447.2 MB |
| M2_IP_3_S116_L007_R1_001.fastq.gz | OTHER | 470.8 MB |
| M2_IP_3_S116_L007_R1_001.fastq.gz | OTHER | 470.8 MB |
| M2_IP_3_S116_L007_R1_001.fastq.gz | OTHER | 470.8 MB |
| M3_INPUT_1_S75_L005_R1_001.fastq.gz | OTHER | 482.2 MB |
| M3_INPUT_1_S75_L005_R1_001.fastq.gz | OTHER | 482.2 MB |
| M3_INPUT_1_S75_L005_R1_001.fastq.gz | OTHER | 482.2 MB |
| M3_INPUT_2_S94_L006_R1_001.fastq.gz | OTHER | 399.7 MB |
| M3_INPUT_2_S94_L006_R1_001.fastq.gz | OTHER | 399.7 MB |
| M3_INPUT_2_S94_L006_R1_001.fastq.gz | OTHER | 399.7 MB |
| M3_INPUT_3_S124_L007_R1_001.fastq.gz | OTHER | 408.8 MB |
| M3_INPUT_3_S124_L007_R1_001.fastq.gz | OTHER | 408.8 MB |
| M3_INPUT_3_S124_L007_R1_001.fastq.gz | OTHER | 408.8 MB |
| M3_IP_1_S68_L005_R1_001.fastq.gz | OTHER | 370.5 MB |
| M3_IP_1_S68_L005_R1_001.fastq.gz | OTHER | 370.5 MB |
| M3_IP_1_S68_L005_R1_001.fastq.gz | OTHER | 370.5 MB |
| M3_IP_2_S87_L006_R1_001.fastq.gz | OTHER | 578.7 MB |
| M3_IP_2_S87_L006_R1_001.fastq.gz | OTHER | 578.7 MB |
| M3_IP_2_S87_L006_R1_001.fastq.gz | OTHER | 578.7 MB |
| M3_IP_3_S117_L007_R1_001.fastq.gz | OTHER | 570.3 MB |
| M3_IP_3_S117_L007_R1_001.fastq.gz | OTHER | 570.3 MB |
| M3_IP_3_S117_L007_R1_001.fastq.gz | OTHER | 570.3 MB |
| SRR31773489 | OTHER | 493.6 MB |
| SRR31773489 | OTHER | 493.6 MB |
| SRR31773490.lite | OTHER | 357.5 MB |
| SRR31773490.lite | OTHER | 357.5 MB |
| SRR31773492 | OTHER | 397.2 MB |
| SRR31773492 | OTHER | 397.2 MB |
| SRR31773493 | OTHER | 301.6 MB |
| SRR31773493 | OTHER | 301.6 MB |
Potentially Related Datasets (1)
These accessions were text-mined from the PMC full text. They may be referenced for comparison, cited from other studies, or otherwise mentioned without being primary data for this paper.
Analysis Pipelines (1)
GSE284636 eCLIP Data Processing
10 steps