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1 result for “iCLIP”
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Pairing beyond the Seed Supports MicroRNA Targeting Specificity.
Molecular cell · 2016 · 64(2): 320-333
To identify endogenous miRNA-target sites, we isolated AGO-bound RNAs from Caenorhabditis elegans by individual-nucleotide resolution crosslinking immunoprecipitation (iCLIP), which fortuitously also produced miRNA-target chimeric reads. Through the analysis of thousands of reproducible chimeras, pairing to the miRNA seed emerged as …
PMID 27720646 DOI ↗
Datasets 11
HNRNPA2B1 regulates alternative RNA processing in the nervous system and accumulates in granules in ALS IPSC-derived motor neurons [iCLIP-seq]
Mus musculus · GPL13112
Enhanced CLIP (eCLIP) enables robust and scalable transcriptome-wide discovery and characterization of RNA binding protein binding sites [iCLIP]
Homo sapiens · GPL16791
Individual nucleotide resolution Crosslinking Immunoprecipitation (iCLIP)-seq
Homo sapiens · GPL11154
Analyses 4
GSE136907 · 2 steps · RIP-Seq · code_examples
Suppression of Endothelial AGO1 Promotes Adipose Tissue Browning and Improves Metabolic Dysfunction. (2020)
GSE77633 · 7 steps · RIP-Seq · code_examples
Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP). (2016)
GSE86041 · 7 steps · RIP-Seq · code_examples
Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System. (2016)
GSE72500 · 3 steps · RIP-Seq · code_examples
The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression. (2015)