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1 result for “insulin secretion”

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  1. A role for alternative splicing in circadian control of exocytosis and glucose homeostasis.

    Genes & development · 2020 · 34(15-16): 1089-1105

    The circadian clock is encoded by a negative transcriptional feedback loop that coordinates physiology and behavior through molecular programs that remain incompletely understood. Here, we reveal rhythmic genome-wide alternative splicing (AS) of pre-mRNAs encoding regulators of peptidergic secretion within pancreatic …

    PMID 32616519 DOI ↗

Datasets 4

GSE68618 GSE · GEO

Aging-dependent demethylation of regulatory elements correlates with chromatin state and improved insulin secretion by pancreatic β cells

Mus musculus · GPL13112

GSE92602 GSE · GEO

Identification of islet-enriched long non-coding RNAs contributing to beta-cell failure in type 2 diabetes

Mus musculus · GPL9250

GSE69889 GSE · GEO

Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk

Mus musculus · GPL17021

GSE146916 GSE · GEO

A role for alternative splicing in circadian control of insulin secretion and glucose homeostasis

Mus musculus · GPL19057

Analyses 3

GSE146916 Processing Pipeline

GSE146916 · 4 steps · RNA-Seq · code_examples

A role for alternative splicing in circadian control of exocytosis and glucose homeostasis. (2020)

GSE69889 Processing Pipeline

GSE69889 · 5 steps · RNA-Seq · code_examples

A role for alternative splicing in circadian control of exocytosis and glucose homeostasis. (2020)

GSE68618 Processing Pipeline

GSE68618 · 11 steps · ChIP-Seq · code_examples

Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation. (2017)