Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes.
Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ri…
Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer.
A CRISPR RNA-binding protein screen reveals regulators of RUNX1 isoform generation.
The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models o…
Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular str…
Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS.
A multi-scale map of cell structure fusing protein images and interactions.
ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses.