A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.
Rainer W J Kaiser,
Michael Ignarski,
Eric L Van Nostrand,
Christian K Frese,
Manaswita Jain,
Sadrija Cukoski,
Heide Heinen,
Melanie Schaechter,
Lisa Seufert,
Konstantin Bunte,
Peter Frommolt,
Patrick Keller,
Mark Helm,
Katrin Bohl,
Martin Höhne,
Bernhard Schermer,
Thomas Benzing,
Katja Höpker,
Christoph Dieterich,
Gene W Yeo,
Roman-Ulrich Müller,
Francesca Fabretti
Scientific reports
· 2019
· Vol. 9
(1)
· pp. 11071
Abstract
AATF is a central regulator of the cellular outcome upon p53 activation, a finding that has primarily been attributed to its function as a transcription factor. Recent data showed that AATF is essential for ribosome biogenesis and plays a role in rRNA maturation. AATF has been implicated to fulfil this role through direct interaction with rRNA and was identified in several RNA-interactome capture experiments. Here, we provide a first comprehensive analysis of the RNA bound by AATF using CLIP-sequencing. Interestingly, this approach shows predominant binding of the 45S pre-ribosomal RNA precursor molecules. Furthermore, AATF binds to mRNAs encoding for ribosome biogenesis factors as well as snoRNAs. These findings are complemented by an in-depth analysis of the protein interactome of AATF containing a large set of proteins known to play a role in rRNA maturation with an emphasis on the protein-RNA-complexes known to be required for the generation of the small ribosomal subunit (SSU). In line with this finding, the binding sites of AATF within the 45S rRNA precursor localize in close proximity to the SSU cleavage sites. Consequently, our multilayer analysis of the protein-RNA interactome of AATF reveals this protein to be an important hub for protein and RNA interactions involved in ribosome biogenesis.
Publication Types
["Journal Article", "Research Support, N.I.H., Extramural", "Research Support, Non-U.S. Gov't"]
Keywords
MeSH Terms
["Animals", "Apoptosis Regulatory Proteins", "Binding Sites", "Cell Line", "HEK293 Cells", "Humans", "Mice", "Protein Binding", "RNA Precursors", "Repressor Proteins", "Ribosomal Proteins", "Ribosome Subunits, Small", "Ribosomes"]
Funding
R00 HG009530
NHGRI NIH HHS
(United States)
K99 HG009530
NHGRI NIH HHS
(United States)
U54 HG007005
NHGRI NIH HHS
(United States)
R01 NS075449
NINDS NIH HHS
(United States)
Linked Datasets (3)
Best practices for eCLIP experiments and analysis [uncertain quality]
Homo sapiens159 data files
| File | Type | Size |
|---|---|---|
| 264_01.R1.fastq.gz | OTHER | 203.3 MB |
| 264_02.R1.fastq.gz | OTHER | 127.3 MB |
| 264_INPUT_GAGATTCC-AGGCGAAG_L001_R1.unassigned.barcoded.fas… | OTHER | 287.1 MB |
| 266_01.R1.fastq.gz | OTHER | 282.9 MB |
| 266_02.R1.fastq.gz | OTHER | 289.5 MB |
| 266_INPUT_ATTCAGAA-GGCTCTGA_L006_R1.unassigned.barcoded.fas… | OTHER | 646.0 MB |
| 299_01.R1.fastq.gz | OTHER | 844.6 MB |
| 299_02.R1.fastq.gz | OTHER | 1.2 GB |
| 299_INPUT_ATTACTCG-AGG_L003_R1.unassigned.barcoded.fastq.gz | OTHER | 301.1 MB |
| 332_01.R1.fastq.gz | OTHER | 385.2 MB |
| 332_02.R1.fastq.gz | OTHER | 352.5 MB |
| 332_INPUT_GAATTCGT-TATAGCCT_L002_R1.unassigned.barcoded.fas… | OTHER | 612.8 MB |
| 355_01_4000.R1.fastq.gz | OTHER | 818.0 MB |
| 355_02_4000.R1.fastq.gz | OTHER | 760.6 MB |
| 355_INPUT_ATTCAGAA-AGGCGAAG_L001_R1.unassigned.barcoded.fas… | OTHER | 136.3 MB |
| 366_01.R1.fastq.gz | OTHER | 487.5 MB |
| 366_02.R1.fastq.gz | OTHER | 479.6 MB |
| 366_INPUT_ATTACTCG-CCTATCCT_L006_R1.unassigned.barcoded.fas… | OTHER | 529.1 MB |
| 415_01.R1.fastq.gz | OTHER | 475.3 MB |
| 415_02.R1.fastq.gz | OTHER | 354.4 MB |
| 415_INPUT_ATTCAGAA-ATAGAGGC_L006_R1.unassigned.barcoded.fas… | OTHER | 675.6 MB |
| 417_01.R1.fastq.gz | OTHER | 913.4 MB |
| 417_02.R1.fastq.gz | OTHER | 1.0 GB |
| 417_INPUT_S56_L006_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1017.0 MB |
| 419_01.R1.fastq.gz | OTHER | 1.1 GB |
| 419_02.R1.fastq.gz | OTHER | 1.0 GB |
| 419_INPUT_S14_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 932.5 MB |
| 451_01_4000.R1.fastq.gz | OTHER | 880.5 MB |
| 451_02_4000.R1.fastq.gz | OTHER | 1.6 GB |
| 451_INPUT_4000_S82_L006_R1_001.unassigned.barcoded.fastq.gz | OTHER | 321.5 MB |
| 459_01.R1.fastq.gz | OTHER | 881.2 MB |
| 459_02.R1.fastq.gz | OTHER | 643.9 MB |
| 459_INPUT_S30_L003_R1_001.unassigned.barcoded.fastq.gz | OTHER | 984.7 MB |
| 463_01.R1.fastq.gz | OTHER | 315.9 MB |
| 463_02.R1.fastq.gz | OTHER | 277.2 MB |
| 463_INPUT_GAGATTCC-CCTATCCT_L003_R1.unassigned.barcoded.fas… | OTHER | 372.5 MB |
| 471_01.R1.fastq.gz | OTHER | 250.4 MB |
| 471_02.R1.fastq.gz | OTHER | 580.5 MB |
| 471_INPUT_S28_L003_R1_001.unassigned.barcoded.fastq.gz | OTHER | 482.4 MB |
| 485_01_4000.R1.fastq.gz | OTHER | 3.4 GB |
| 485_02_4000.R1.fastq.gz | OTHER | 2.6 GB |
| 485_INPUT_S42_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.6 GB |
| 496_01.R1.fastq.gz | OTHER | 1.1 GB |
| 496_02.R1.fastq.gz | OTHER | 1.1 GB |
| 496_INPUT_S69_L008_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.0 GB |
| 498_01.R1.fastq.gz | OTHER | 896.5 MB |
| 498_02.R1.fastq.gz | OTHER | 735.4 MB |
| 498_INPUT_S46_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 972.8 MB |
| 499_01.R1.fastq.gz | OTHER | 982.6 MB |
| 499_02.R1.fastq.gz | OTHER | 1016.3 MB |
| 499_INPUT_S48_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 850.1 MB |
| 510_01.R1.fastq.gz | OTHER | 760.9 MB |
| 510_02.R1.fastq.gz | OTHER | 765.4 MB |
| 510_INPUT_S4_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.1 GB |
| 512_01.R1.fastq.gz | OTHER | 1.1 GB |
| 512_02.R1.fastq.gz | OTHER | 1.1 GB |
| 512_INPUT_S67_L008_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.1 GB |
| 513_01.R1.fastq.gz | OTHER | 744.3 MB |
| 513_02.R1.fastq.gz | OTHER | 767.8 MB |
| 513_INPUT_S45_L004_R1_001.unassigned.barcoded.fastq.gz | OTHER | 998.9 MB |
| 520_01.R1.fastq.gz | OTHER | 603.6 MB |
| 520_02.R1.fastq.gz | OTHER | 706.1 MB |
| 520_INPUT_S24_L003_R1_001.unassigned.barcoded.fastq.gz | OTHER | 747.8 MB |
| 523_01.R1.fastq.gz | OTHER | 816.2 MB |
| 523_02.R1.fastq.gz | OTHER | 910.6 MB |
| 523_INPUT_S6_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 996.8 MB |
| 529_01.R1.fastq.gz | OTHER | 963.1 MB |
| 529_02.R1.fastq.gz | OTHER | 688.0 MB |
| 529_INPUT_S16_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 852.8 MB |
| 531_01.R1.fastq.gz | OTHER | 908.5 MB |
| 531_02.R1.fastq.gz | OTHER | 875.8 MB |
| 531_INPUT_S8_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 933.7 MB |
| 534_01.R1.fastq.gz | OTHER | 806.6 MB |
| 534_02.R1.fastq.gz | OTHER | 500.0 MB |
| 534_INPUT_S2_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 644.6 MB |
| 535_01.R1.fastq.gz | OTHER | 719.9 MB |
| 535_02.R1.fastq.gz | OTHER | 866.2 MB |
| 535_INPUT_S57_L006_R1_001.unassigned.barcoded.fastq.gz | OTHER | 695.3 MB |
| 536_01.R1.fastq.gz | OTHER | 693.7 MB |
| 536_02.R1.fastq.gz | OTHER | 687.3 MB |
| 536_INPUT_S23_L003_R1_001.unassigned.barcoded.fastq.gz | OTHER | 866.0 MB |
| 541_01.R1.fastq.gz | OTHER | 518.8 MB |
| 541_02.R1.fastq.gz | OTHER | 698.8 MB |
| 541_INPUT_S61_L007_R1_001.unassigned.barcoded.fastq.gz | OTHER | 607.0 MB |
| 547_01.R1.fastq.gz | OTHER | 1020.2 MB |
| 547_02.R1.fastq.gz | OTHER | 1.0 GB |
| 547_INPUT_S5_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.1 GB |
| 555_01.R1.fastq.gz | OTHER | 534.4 MB |
| 555_02.R1.fastq.gz | OTHER | 977.8 MB |
| 555_INPUT_S5_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.3 GB |
| 567_01.R1.fastq.gz | OTHER | 576.2 MB |
| 567_02.R1.fastq.gz | OTHER | 684.5 MB |
| 567_INPUT_S52_L006_R1_001.unassigned.barcoded.fastq.gz | OTHER | 798.5 MB |
| 588_01.R1.fastq.gz | OTHER | 726.0 MB |
| 588_02.R1.fastq.gz | OTHER | 841.6 MB |
| 588_INPUT_S52_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.0 GB |
| 598_01.R1.fastq.gz | OTHER | 513.2 MB |
| 598_02.R1.fastq.gz | OTHER | 737.3 MB |
| 598_INPUT_S18_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 932.4 MB |
| 609_01.R1.fastq.gz | OTHER | 1.2 GB |
| 609_02.R1.fastq.gz | OTHER | 946.4 MB |
| 609_INPUT_S39_L004_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.2 GB |
| 611_01.R1.fastq.gz | OTHER | 745.3 MB |
| 611_02.R1.fastq.gz | OTHER | 277.4 MB |
| 611_INPUT_S30_L003_R1_001.unassigned.barcoded.fastq.gz | OTHER | 676.5 MB |
| 613_01.R1.fastq.gz | OTHER | 764.7 MB |
| 613_02.R1.fastq.gz | OTHER | 894.3 MB |
| 613_INPUT_S44_L004_R1_001.unassigned.barcoded.fastq.gz | OTHER | 882.6 MB |
| 616_01.R1.fastq.gz | OTHER | 757.2 MB |
| 616_02.R1.fastq.gz | OTHER | 815.1 MB |
| 616_INPUT_S6_L004_R1_001.unassigned.barcoded.fastq.gz | OTHER | 837.8 MB |
| 626_01.R1.fastq.gz | OTHER | 908.0 MB |
| 626_01.R2.fastq.gz | OTHER | 908.0 MB |
| 626_02.R1.fastq.gz | OTHER | 679.2 MB |
| 626_INPUT_S14_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 736.2 MB |
| 647_01.R1.fastq.gz | OTHER | 331.9 MB |
| 647_02.R1.fastq.gz | OTHER | 1.3 GB |
| 647_INPUT_S24_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 877.9 MB |
| 658_01.R1.fastq.gz | OTHER | 550.1 MB |
| 658_02.R1.fastq.gz | OTHER | 657.0 MB |
| 658_INPUT_S27_L003_R1_001.unassigned.barcoded.fastq.gz | OTHER | 835.0 MB |
| 658_INPUT_S27_L003_R2_001.unassigned.barcoded.fastq.gz | OTHER | 835.0 MB |
| 662_01.R1.fastq.gz | OTHER | 1.1 GB |
| 662_02.R1.fastq.gz | OTHER | 882.5 MB |
| 662_INPUT_S7_L006_R1_001.unassigned.barcoded.fastq.gz | OTHER | 679.5 MB |
| 669_01.R1.fastq.gz | OTHER | 1.7 GB |
| 669_02.R1.fastq.gz | OTHER | 201.3 MB |
| 669_INPUT_S12_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 788.4 MB |
| 674_01.R1.fastq.gz | OTHER | 545.2 MB |
| 674_02.R1.fastq.gz | OTHER | 574.0 MB |
| 674_INPUT_S78_L004_R1_001.unassigned.barcoded.fastq.gz | OTHER | 806.4 MB |
| 674_INPUT_S78_L004_R2_001.unassigned.barcoded.fastq.gz | OTHER | 806.4 MB |
| 679_01.R1.fastq.gz | OTHER | 843.1 MB |
| 679_02.R1.fastq.gz | OTHER | 604.8 MB |
| 679_02.R2.fastq.gz | OTHER | 604.8 MB |
| 679_INPUT_S31_L003_R1_001.unassigned.barcoded.fastq.gz | OTHER | 958.0 MB |
| 706_01.R1.fastq.gz | OTHER | 1.1 GB |
| 706_02.R1.fastq.gz | OTHER | 1.9 GB |
| 706_INPUT_S49_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 647.6 MB |
| 714_01.R1.fastq.gz | OTHER | 397.0 MB |
| 714_02.R1.fastq.gz | OTHER | 461.9 MB |
| 714_INPUT_S34_L004_R1_001.unassigned.barcoded.fastq.gz | OTHER | 532.5 MB |
| 721_01.R1.fastq.gz | OTHER | 1.1 GB |
| 721_02.R1.fastq.gz | OTHER | 735.5 MB |
| 721_INPUT_S77_L007_R1_001.unassigned.barcoded.fastq.gz | OTHER | 732.9 MB |
| 724_01.R1.fastq.gz | OTHER | 770.7 MB |
| 724_02.R1.fastq.gz | OTHER | 708.9 MB |
| 724_INPUT_S83_L008_R1_001.unassigned.barcoded.fastq.gz | OTHER | 647.5 MB |
| 739_01.R1.fastq.gz | OTHER | 911.7 MB |
| 739_02.R1.fastq.gz | OTHER | 870.9 MB |
| 739_INPUT_S112_L008_R1_001.unassigned.barcoded.fastq.gz | OTHER | 712.9 MB |
| 761_01.R1.fastq.gz | OTHER | 612.5 MB |
| 761_02.R1.fastq.gz | OTHER | 619.9 MB |
| 761_02.R2.fastq.gz | OTHER | 619.9 MB |
| 761_INPUT_S4_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 760.1 MB |
| SRR6458762 | OTHER | 647.5 MB |
| SRR7889847 | OTHER | 354.4 MB |
| SRR7889875 | OTHER | 1017.0 MB |
| SRR7889879 | OTHER | 1.0 GB |
Best practices for eCLIP experiments and analysis [poor quality]
Homo sapiens229 data files
| File | Type | Size |
|---|---|---|
| 202_01.R1.fastq.gz | OTHER | 97.0 MB |
| 202_02.R1.fastq.gz | OTHER | 360.5 MB |
| 214_01.R1.fastq.gz | OTHER | 300.1 MB |
| 214_INPUT_GAATTCGT-ATAGAGGC_L003_R1.unassigned.barcoded.fas… | OTHER | 584.6 MB |
| 219_01.R1.fastq.gz | OTHER | 372.7 MB |
| 219_02.R1.fastq.gz | OTHER | 212.9 MB |
| 219_INPUT_GAATTCGT-AGGCGAAG_L003_R1.unassigned.barcoded.fas… | OTHER | 436.6 MB |
| 225_01.R1.fastq.gz | OTHER | 145.0 MB |
| 225_02.R1.fastq.gz | OTHER | 36.0 MB |
| 225_INPUT_TCCGGAGA-TAATCTTA_L001_R1.unassigned.barcoded.fas… | OTHER | 386.5 MB |
| 232_01.R1.fastq.gz | OTHER | 367.4 MB |
| 232_02.R1.fastq.gz | OTHER | 301.5 MB |
| 232_INPUT_GAATTCGT-AGGCGAAG_L002_R1.unassigned.barcoded.fas… | OTHER | 501.5 MB |
| 234_01.R1.fastq.gz | OTHER | 381.4 MB |
| 246_01.R1.fastq.gz | OTHER | 444.2 MB |
| 246_02.R1.fastq.gz | OTHER | 452.3 MB |
| 246_INPUT_GAGATTCC-GGCTCTGA_L003_R1.unassigned.barcoded.fas… | OTHER | 777.9 MB |
| 254_01.R1.fastq.gz | OTHER | 356.9 MB |
| 254_02.R1.fastq.gz | OTHER | 339.6 MB |
| 254_INPUT_GAGATTCC-TAATCTTA_L006_R1.unassigned.barcoded.fas… | OTHER | 510.2 MB |
| 255_01.R1.fastq.gz | OTHER | 549.4 MB |
| 255_02.R1.fastq.gz | OTHER | 443.0 MB |
| 255_INPUT_ATTACTCG-TATAGCCT_L004_R1.unassigned.barcoded.fas… | OTHER | 728.4 MB |
| 280_01.R1.fastq.gz | OTHER | 447.1 MB |
| 280_02.R1.fastq.gz | OTHER | 501.8 MB |
| 280_INPUT_ATTACTCG-TATAGCCT_L001_R1.unassigned.barcoded.fas… | OTHER | 634.1 MB |
| 290_01.R1.fastq.gz | OTHER | 586.3 MB |
| 290_02.R1.fastq.gz | OTHER | 869.8 MB |
| 290_INPUT_ATTACTCG-TATAGCCT_L001_R1.unassigned.barcoded.fas… | OTHER | 914.9 MB |
| 300_01.R1.fastq.gz | OTHER | 463.7 MB |
| 300_02.R1.fastq.gz | OTHER | 400.1 MB |
| 300_INPUT_CGCTCATT-TAATCTTA_L001_R1.unassigned.barcoded.fas… | OTHER | 819.9 MB |
| 317_01.R1.fastq.gz | OTHER | 352.3 MB |
| 317_02.R1.fastq.gz | OTHER | 284.4 MB |
| 317_INPUT_GAGATTCC-ATAGAGGC_L002_R1.unassigned.barcoded.fas… | OTHER | 678.6 MB |
| 323_01_4000.R1.fastq.gz | OTHER | 805.4 MB |
| 323_02_4000.R1.fastq.gz | OTHER | 832.8 MB |
| 323_INPUT_TCCGGAGA-ATAGAGGC_L001_R1.unassigned.barcoded.fas… | OTHER | 593.9 MB |
| 327_01.R1.fastq.gz | OTHER | 299.6 MB |
| 327_02.R1.fastq.gz | OTHER | 323.3 MB |
| 327_INPUT_TCCGGAGA-TATAGCCT_L001_R1.unassigned.barcoded.fas… | OTHER | 492.0 MB |
| 328_01.R1.fastq.gz | OTHER | 295.0 MB |
| 328_02.R1.fastq.gz | OTHER | 312.3 MB |
| 328_INPUT_GAGATTCC-TATAGCCT_L002_R1.unassigned.barcoded.fas… | OTHER | 697.2 MB |
| 333_01_4000.R1.fastq.gz | OTHER | 1.2 GB |
| 333_02_4000.R1.fastq.gz | OTHER | 806.7 MB |
| 333_INPUT_CGCTCATT-CCTATCCT_L001_R1.unassigned.barcoded.fas… | OTHER | 926.1 MB |
| 351_01.R1.fastq.gz | OTHER | 348.5 MB |
| 351_02.R1.fastq.gz | OTHER | 191.6 MB |
| 351_INPUT_S8_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 838.2 MB |
| 356_01.R1.fastq.gz | OTHER | 337.0 MB |
| 356_02.R1.fastq.gz | OTHER | 294.3 MB |
| 356_INPUT_TCCGGAGA-GGCTCTGA_L001_R1.unassigned.barcoded.fas… | OTHER | 593.5 MB |
| 363_01_4000.R1.fastq.gz | OTHER | 1.2 GB |
| 363_02_4000.R1.fastq.gz | OTHER | 1.5 GB |
| 363_INPUT_4000_S18_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1006.1 MB |
| 386_01_4000.R1.fastq.gz | OTHER | 1.4 GB |
| 386_02_4000.R1.fastq.gz | OTHER | 1.5 GB |
| 386_INPUT_4000_S19_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 780.5 MB |
| 396_01.R1.fastq.gz | OTHER | 668.1 MB |
| 396_02.R1.fastq.gz | OTHER | 669.6 MB |
| 396_INPUT_ATTACTCG-CCTATCCT_L004_R1.unassigned.barcoded.fas… | OTHER | 1.3 GB |
| 397_01.R1.fastq.gz | OTHER | 840.6 MB |
| 397_02.R1.fastq.gz | OTHER | 1.1 GB |
| 397_INPUT_ATTACTCG-AGGCGAAG_L006_R1.unassigned.barcoded.fas… | OTHER | 401.2 MB |
| 403_01_4000.R1.fastq.gz | OTHER | 924.3 MB |
| 403_02_4000.R1.fastq.gz | OTHER | 1.2 GB |
| 403_INPUT_4000_S80_L006_R1_001.unassigned.barcoded.fastq.gz | OTHER | 516.8 MB |
| 407_01.R1.fastq.gz | OTHER | 922.8 MB |
| 407_02.R1.fastq.gz | OTHER | 713.2 MB |
| 407_INPUT_S5_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.1 GB |
| 429_01.R1.fastq.gz | OTHER | 359.0 MB |
| 429_02.R1.fastq.gz | OTHER | 200.1 MB |
| 429_INPUT_GAATTCGT-ATAGAGGC_L004_R1.unassigned.barcoded.fas… | OTHER | 1015.2 MB |
| 430_01.R1.fastq.gz | OTHER | 633.8 MB |
| 430_02.R1.fastq.gz | OTHER | 648.3 MB |
| 430_INPUT_S16_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 901.9 MB |
| 467_01.R1.fastq.gz | OTHER | 635.0 MB |
| 467_02.R1.fastq.gz | OTHER | 752.6 MB |
| 467_INPUT_S18_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 853.1 MB |
| 472_01.R1.fastq.gz | OTHER | 669.5 MB |
| 472_02.R1.fastq.gz | OTHER | 190.2 MB |
| 472_INPUT_S12_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 921.5 MB |
| 474_01.R1.fastq.gz | OTHER | 635.6 MB |
| 474_02.R1.fastq.gz | OTHER | 856.6 MB |
| 474_INPUT_S43_L004_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.1 GB |
| 479_01.R1.fastq.gz | OTHER | 506.5 MB |
| 479_02.R1.fastq.gz | OTHER | 735.5 MB |
| 479_INPUT_S20_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 688.0 MB |
| 486_01_4000.R1.fastq.gz | OTHER | 2.0 GB |
| 486_02_4000.R1.fastq.gz | OTHER | 2.2 GB |
| 486_INPUT_S44_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.2 GB |
| 500_01.R1.fastq.gz | OTHER | 773.8 MB |
| 500_02.R1.fastq.gz | OTHER | 730.7 MB |
| 500_INPUT_S4_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 884.5 MB |
| 528_01.R1.fastq.gz | OTHER | 119.8 MB |
| 528_02.R1.fastq.gz | OTHER | 127.3 MB |
| 528_INPUT_S14_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 215.7 MB |
| 542_01.R1.fastq.gz | OTHER | 895.9 MB |
| 542_02.R1.fastq.gz | OTHER | 901.9 MB |
| 542_INPUT_S33_L004_R1_001.unassigned.barcoded.fastq.gz | OTHER | 817.7 MB |
| 554_01.R1.fastq.gz | OTHER | 566.1 MB |
| 554_02.R1.fastq.gz | OTHER | 627.9 MB |
| 554_INPUT_S59_L007_R1_001.unassigned.barcoded.fastq.gz | OTHER | 841.8 MB |
| 557_01.R1.fastq.gz | OTHER | 992.1 MB |
| 557_02.R1.fastq.gz | OTHER | 308.2 MB |
| 557_INPUT_S45_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.2 GB |
| 573_01.R1.fastq.gz | OTHER | 231.1 MB |
| 573_02.R1.fastq.gz | OTHER | 1.5 GB |
| 573_INPUT_S50_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 283.0 MB |
| 579_01.R1.fastq.gz | OTHER | 888.9 MB |
| 579_02.R1.fastq.gz | OTHER | 973.2 MB |
| 579_INPUT_S50_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 869.3 MB |
| 580_01.R1.fastq.gz | OTHER | 617.9 MB |
| 580_02.R1.fastq.gz | OTHER | 458.7 MB |
| 580_INPUT_S12_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 454.6 MB |
| 590_01.R1.fastq.gz | OTHER | 1003.3 MB |
| 590_02.R1.fastq.gz | OTHER | 643.2 MB |
| 590_INPUT_S8_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 776.6 MB |
| 591_01.R1.fastq.gz | OTHER | 894.2 MB |
| 591_02.R1.fastq.gz | OTHER | 540.0 MB |
| 591_INPUT_S14_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 674.1 MB |
| 594_01.R1.fastq.gz | OTHER | 858.5 MB |
| 594_02.R1.fastq.gz | OTHER | 533.7 MB |
| 594_INPUT_S24_L003_R1_001.unassigned.barcoded.fastq.gz | OTHER | 689.4 MB |
| 597_01.R1.fastq.gz | OTHER | 209.2 MB |
| 597_02.R1.fastq.gz | OTHER | 330.0 MB |
| 597_INPUT_S6_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 602.7 MB |
| 599_01.R1.fastq.gz | OTHER | 248.3 MB |
| 599_02.R1.fastq.gz | OTHER | 301.1 MB |
| 599_INPUT_S8_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 493.5 MB |
| 618_01.R1.fastq.gz | OTHER | 1.2 GB |
| 618_02.R1.fastq.gz | OTHER | 964.0 MB |
| 618_INPUT_S48_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.1 GB |
| 622_01.R1.fastq.gz | OTHER | 436.9 MB |
| 622_02.R1.fastq.gz | OTHER | 564.9 MB |
| 622_INPUT_S28_L003_R1_001.unassigned.barcoded.fastq.gz | OTHER | 571.1 MB |
| 627_01.R1.fastq.gz | OTHER | 515.4 MB |
| 627_02.R1.fastq.gz | OTHER | 572.7 MB |
| 627_INPUT_S10_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 918.3 MB |
| 630_01.R1.fastq.gz | OTHER | 691.3 MB |
| 630_02.R1.fastq.gz | OTHER | 604.1 MB |
| 630_02.R2.fastq.gz | OTHER | 604.1 MB |
| 630_INPUT_S24_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.2 GB |
| 634_01.R1.fastq.gz | OTHER | 183.0 MB |
| 634_02.R1.fastq.gz | OTHER | 164.4 MB |
| 634_INPUT_S4_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 562.5 MB |
| 635_01.R1.fastq.gz | OTHER | 264.3 MB |
| 635_02.R1.fastq.gz | OTHER | 359.8 MB |
| 635_INPUT_S6_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 633.9 MB |
| 636_01.R1.fastq.gz | OTHER | 212.7 MB |
| 636_02.R1.fastq.gz | OTHER | 265.5 MB |
| 636_INPUT_S10_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 769.6 MB |
| 637_01.R1.fastq.gz | OTHER | 877.8 MB |
| 637_02.R1.fastq.gz | OTHER | 698.2 MB |
| 637_INPUT_S109_L008_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1017.1 MB |
| 648_01.R1.fastq.gz | OTHER | 487.9 MB |
| 648_02.R1.fastq.gz | OTHER | 30.6 MB |
| 648_INPUT_S8_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 588.5 MB |
| 657_01.R1.fastq.gz | OTHER | 351.1 MB |
| 657_02.R1.fastq.gz | OTHER | 675.1 MB |
| 657_INPUT_S29_L003_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.0 GB |
| 666_01.R1.fastq.gz | OTHER | 443.5 MB |
| 666_02.R1.fastq.gz | OTHER | 589.1 MB |
| 666_INPUT_S41_L004_R1_001.unassigned.barcoded.fastq.gz | OTHER | 4.8 GB |
| 671_01.R1.fastq.gz | OTHER | 249.5 MB |
| 671_02.R1.fastq.gz | OTHER | 227.8 MB |
| 671_INPUT_S8_L001_R1_001.unassigned.barcoded.fastq.gz | OTHER | 377.1 MB |
| 673_01.R1.fastq.gz | OTHER | 310.5 MB |
| 673_02.R1.fastq.gz | OTHER | 856.1 MB |
| 673_INPUT_S37_L003_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.2 GB |
| 687_01.R1.fastq.gz | OTHER | 631.2 MB |
| 687_02.R1.fastq.gz | OTHER | 1020.4 MB |
| 687_INPUT_S16_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 811.6 MB |
| 688_01.R1.fastq.gz | OTHER | 900.5 MB |
| 688_02.R1.fastq.gz | OTHER | 1.2 GB |
| 688_INPUT_S18_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 887.0 MB |
| 691_01.R1.fastq.gz | OTHER | 553.2 MB |
| 691_02.R1.fastq.gz | OTHER | 347.9 MB |
| 691_INPUT_S35_L003_R1_001.unassigned.barcoded.fastq.gz | OTHER | 468.4 MB |
| 701_01.R1.fastq.gz | OTHER | 284.4 MB |
| 701_02.R1.fastq.gz | OTHER | 810.9 MB |
| 701_INPUT_S5_L003_R1_001.unassigned.barcoded.fastq.gz | OTHER | 882.8 MB |
| 704_01.R1.fastq.gz | OTHER | 1.0 GB |
| 704_02.R1.fastq.gz | OTHER | 935.1 MB |
| 704_INPUT_S85_L008_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.3 GB |
| 710_01.R1.fastq.gz | OTHER | 579.5 MB |
| 710_02.R1.fastq.gz | OTHER | 603.5 MB |
| 710_INPUT_S53_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1018.7 MB |
| 715_01.R1.fastq.gz | OTHER | 950.0 MB |
| 715_02.R1.fastq.gz | OTHER | 562.3 MB |
| 715_INPUT_S69_L007_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.0 GB |
| 718_01.R1.fastq.gz | OTHER | 773.6 MB |
| 718_02.R1.fastq.gz | OTHER | 939.3 MB |
| 718_INPUT_S71_L007_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1004.0 MB |
| 720_01.R1.fastq.gz | OTHER | 717.7 MB |
| 720_02.R1.fastq.gz | OTHER | 741.5 MB |
| 720_INPUT_S75_L007_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.1 GB |
| 725_01.R1.fastq.gz | OTHER | 520.0 MB |
| 725_02.R1.fastq.gz | OTHER | 525.8 MB |
| 725_INPUT_S16_L002_R1_001.unassigned.barcoded.fastq.gz | OTHER | 319.1 MB |
| 727_01.R1.fastq.gz | OTHER | 750.1 MB |
| 727_02.R1.fastq.gz | OTHER | 452.3 MB |
| 727_INPUT_S63_L006_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1010.0 MB |
| 728_01.R1.fastq.gz | OTHER | 1.2 GB |
| 728_02.R1.fastq.gz | OTHER | 1.1 GB |
| 728_INPUT_S61_L006_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.1 GB |
| 749_01.R1.fastq.gz | OTHER | 762.0 MB |
| 749_02.R1.fastq.gz | OTHER | 722.2 MB |
| 749_INPUT_S89_L008_R1_001.unassigned.barcoded.fastq.gz | OTHER | 822.3 MB |
| 751_01.R1.fastq.gz | OTHER | 500.3 MB |
| 751_02.R1.fastq.gz | OTHER | 560.2 MB |
| 751_INPUT_S36_L004_R1_001.unassigned.barcoded.fastq.gz | OTHER | 776.0 MB |
| 756_01.R1.fastq.gz | OTHER | 743.7 MB |
| 756_02.R1.fastq.gz | OTHER | 811.4 MB |
| 756_INPUT_S48_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 761.7 MB |
| 757_01.R1.fastq.gz | OTHER | 746.5 MB |
| 757_02.R1.fastq.gz | OTHER | 763.6 MB |
| 757_INPUT_S50_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 818.0 MB |
| 758_01.R1.fastq.gz | OTHER | 952.4 MB |
| 758_02.R1.fastq.gz | OTHER | 761.8 MB |
| 758_INPUT_S52_L005_R1_001.unassigned.barcoded.fastq.gz | OTHER | 832.4 MB |
| 759_01.R1.fastq.gz | OTHER | 731.6 MB |
| 759_02.R1.fastq.gz | OTHER | 1.2 GB |
| 759_INPUT_S118_L008_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.1 GB |
| 760_01.R1.fastq.gz | OTHER | 652.7 MB |
| 760_02.R1.fastq.gz | OTHER | 458.8 MB |
| 760_INPUT_S114_L008_R1_001.unassigned.barcoded.fastq.gz | OTHER | 1.1 GB |
| PTBP1-202-INPUT_S6_R1.unassigned.barcoded.fastq.gz | OTHER | 491.3 MB |
Potentially Related Datasets (5)
These accessions were text-mined from the PMC full text. They may be referenced for comparison, cited from other studies, or otherwise mentioned without being primary data for this paper.
eCLIP experiment on K562 against AATF
Analysis Pipelines (3)
GSE107766 eCLIP Data Processing
33 steps
GSE107767 eCLIP Data Processing
33 steps
GSE107768 eCLIP Data Processing
33 steps