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  1. The <i>Thermus thermophilus</i> DEAD-box protein Hera is a general RNA binding protein and plays a key role in tRNA metabolism.

    RNA (New York, N.Y.) · 2020 · 26(11): 1557-1574

    RNA helicases catalyze the ATP-dependent destabilization of RNA duplexes. DEAD-box helicases share a helicase core that mediates ATP binding and hydrolysis, RNA binding and unwinding. Most members of this family contain domains flanking the core that can confer RNA substrate …

    PMID 32669294 DOI ↗

Datasets 25+

GSE244832 GSE · GEO

Multi-Modal Comparison of human Hepatic Stellate Cells identifies novel therapeutic targets for Metabolic Dysfunction-Associated Steatotic Liver Disease

Homo sapiens · GPL24676, GPL37309

GSE313324 GSE · GEO

PUF60-Mediated Splicing Is a Key Driver of Triple Negative Breast Cancer [CRISPR]

GPL24676

GSE280898 GSE · GEO

PUF60-Mediated Splicing Is a Key Driver of Triple Negative Breast Cancer [eCLIP]

GPL24676

GSE280897 GSE · GEO

PUF60-Mediated Splicing Is a Key Driver of Triple Negative Breast Cancer [RNA-seq]

GPL24676

GSE279064 GSE · GEO

LARP6 shapes the mRNA translation of fibrogenic genes [RNA-seq]

GPL24676

GSE278725 GSE · GEO

LARP6 shapes the mRNA translation of fibrogenic genes [eCLIP]

GPL24676

GSE24759 GSE · GEO

Densely interconnected transcriptional circuits control cell states in human hematopoiesis

Homo sapiens · GPL4685

GSE28359 GSE · GEO

Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells

Homo sapiens · GPL570

GSE125490 GSE · GEO

Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal

Mus musculus · GPL13112

GSE134971 GSE · GEO

An In Vivo Genome-Wide CRISPR Screen Identifies the RNA-Binding Protein Staufen2 as a Key Regulator of Myeloid Leukemia

Homo sapiens · GPL16791

GSE135300 GSE · GEO

Next Generation Sequencing: in vivo genome-wide CRISPR sgRNA screen in primary cancer-initiating and propagating bcCML stem cells

Mus musculus · GPL21103

GSE68172 GSE · GEO

LAA expression profiles on LSC compared to other tissues

Homo sapiens · GPL570

GSE84105 GSE · GEO

Defining memory-like CD8 T cells that respond to PD-1 therapy in chronic viral infection

Mus musculus · GPL1261

GSE69889 GSE · GEO

Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk

Mus musculus · GPL17021

GSE5851 GSE · GEO

Phase II exploratory pharmacogenomics study of cetuximab monotherapy in patients with advanced metastatic CRC

Homo sapiens · GPL571

GSE37892 GSE · GEO

A seven-gene signature aggregates a subgroup of stage II colon cancers with stage III.

Homo sapiens · GPL570

GSE87211 GSE · GEO

Colorectal cancer susceptibility loci as predictive markers of rectal cancer prognosis after surgery

Homo sapiens · GPL13497

GSE17536 GSE · GEO

Metastasis Gene Expression Profile Predicts Recurrence and Death in Colon Cancer Patients (Moffitt Samples)

Homo sapiens · GPL570

GSE137258 GSE · GEO

Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer

Homo sapiens · GPL20301

GSE157072 GSE · GEO

RNA-Seq of CD8+ T cell subsets during LCMV infection III

Mus musculus · GPL17021

GSE76008 GSE · GEO

A 17-Gene Stemness Score for Rapid Identification of High-Risk AML Patients [Illumina]

Homo sapiens · GPL10558

GSE121569 GSE · GEO

ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair

Homo sapiens · GPL11154

GSE162335 GSE · GEO

Transcriptional Survey of Ileal-Anal Pouch Immune Cells from Ulcerative Colitis

Homo sapiens · GPL20301

GSE134809 GSE · GEO

Single-cell analysis of Crohn’s disease lesions identifies a pathogenic cellular module associated with resistance to anti-TNF therapy

Homo sapiens · GPL18573

GSE127944 GSE · GEO

In vivo CRISPR screening unveils RNA binding protein dependencies for leukemic stem cells and identifies ELAVL1 as a potential therapeutic target [eCLIPseq]

Mus musculus · GPL21103

Showing first 25 dataset results.

Analyses 13

GSE244832 scRNA-seq Data Processing

GSE244832 · 9 steps · scRNA-seq · geo_data_processing

RNA-binding protein LARP6 coordinates hepatic stellate cell activation and liver fibrosis. (2026)

GSE127743 Processing Pipeline

GSE127743 · 4 steps · RNA-Seq · code_examples

In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target. (2023)

GSE127944 Processing Pipeline

GSE127944 · 22 steps · RIP-Seq · code_examples

In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target. (2023)

GSE134809 Processing Pipeline

GSE134809 · 5 steps · RNA-Seq · code_examples

RNA binding protein DDX5 restricts RORγt<sup>+</sup> T<sub>reg</sub> suppressor function to promote intestine inflammation. (2023)

GSE224548 Processing Pipeline

GSE224548 · 3 steps · RNA-Seq · code_examples

In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target. (2023)

GSE133744 Processing Pipeline

GSE133744 · 1 step · GSE · code_examples

Motoneuron expression profiling identifies an association between an axonal splice variant of HDGF-related protein 3 and peripheral myelination. (2020)

GSE135435 Processing Pipeline

GSE135435 · 29 steps · RIP-Seq · code_examples

The <i>Thermus thermophilus</i> DEAD-box protein Hera is a general RNA binding protein and plays a key role in tRNA metabolism. (2020)

GSE5851 Processing Pipeline

GSE5851 · 1 step · GSE · code_examples

DDX5 promotes oncogene C3 and FABP1 expressions and drives intestinal inflammation and tumorigenesis. (2020)

GSE84105 Processing Pipeline

GSE84105 · 1 step · GSE · code_examples

Heterogenous Populations of Tissue-Resident CD8<sup>+</sup> T Cells Are Generated in Response to Infection and Malignancy. (2020)

GSE74583 Processing Pipeline

GSE74583 · 5 steps · RNA-Seq · code_examples

PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically. (2016)

GSE51684 Processing Pipeline

GSE51684 · 4 steps · RNA-Seq · code_examples

Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. (2013)

GSE51685 Processing Pipeline

GSE51685 · 6 steps · RNA-Seq · code_examples

Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. (2013)

GSE51741 Processing Pipeline

GSE51741 · 4 steps · GSE · code_examples

Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. (2013)