Datasets (2527)

Microsatellite expansion RNA visualization, elimination, and reversal of molecular pathology by RNA-targeting Cas9

Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size (scRNA-seq)

Cancer avatars derived from genetically engineered pluripotent stem cells allow for longitudinal assessment of tumor development

Transcriptome analysis of diverse cell types infected with human cytomegalovirus

Target discrimination in nonsense-mediated mRNA decay requires Upf1 ATPase activity (CLIP-Seq)

Systematic identification of RNA-binding proteins and tethered domains that activate exon splicing inclusion [eCLIP-seq]

Robust single-cell discovery of RNA targets of RNA binding proteins and ribosomes [RNA-seq]

Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_mouse]

Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress

Integrative RNA-omics discovers GNAS alternative splicing as a phenotypic driver of splicing factor mutant neoplasms

MECP2-related pathways are dysregulated in a cortical organoid model of Myotonic dystrophy [scRNA-Seq]

HNRNPA2B1 regulates alternative RNA processing in the nervous system and accumulates in granules in ALS IPSC-derived motor neurons [hnRNPA2B1_Arrays_human_Fibs_2]

Robust single-cell discovery of RNA targets of RNA binding proteins and ribosomes [tia1_eclip]

HNRNPA2B1 regulates alternative RNA processing in the nervous system and accumulates in granules in ALS IPSC-derived motor neurons [iCLIP-seq]

Best practices for eCLIP experiments and analysis

Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [Affymetrix]

Musashi1 is a master regulator of aberrant translation in Group 3 medulloblastoma

RPS19 binding with and without Diamond-Blackfan anemia variants

Gene Expression Signatures of Motor Neuron Populations Isolated from Sporadic ALS

Identification of different transcripts that favor the nuclear or cytoplasmic Poly(A) Binding Proteins (PABPs) through RNA immunoprecipitation

RNA-Targeting CRISPR/Cas13d System Alleviates Disease-Related Phenotypes in Pre-clinical Models of Huntington’s Disease

Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs (RNA-Seq)

Whole brain RNA from congenic littermates does not support a general effect of Nxf1 CAST alleles on alternative pre-mRNA processing

Discovery and functional interrogation of the virus and host RNA interactome of SARS-CoV-2 proteins [RNA-Seq]

RNA-seq in neurites and soma of primary hippocampal neurons isolated from P0 or P1 mice